سوابق پژوهشی

Research Grants

  • Synthesis and Study of Blood-brain Barrier Penetrating Peptides, awarded by National Institute of Genetic Engineering and Biotechnology (NIGEB) 2019
  • Synthesis and Comparative Study of Novel and Unspecific Cell-penetrating Peptides for Carrying Drugs and Fluorescent Probes into Cells, awarded by Iran National Science Foundation (INSF) 2018
  • Synthesis Oligoasparatate and Oligoarginine Peptides and Compare their Cell-penetrating Capability, awarded by National Institute of Genetic Engineering and Biotechnology (NIGEB) 2018
  • Synthesis and Dynamic Evaluation of Super Flexible Peptides for Binding to Hydrophobic Guest-molecules, awarded by National Institute of Genetic Engineering and Biotechnology (NIGEB) 2017
  • Design and Synthesis new Oligopeptides Against Tumor Antigenes, awarded by National Elites Foundation 2016

Supervised Dissertations

  • Synthesis, penetration assessment and study of the effect of blood-brain barrier shuttle peptides on the expression of Nrf2 gene, 2022, Ph.D
  • Comparing the Cell-penetrating Efficiency of the Short-peptides with Opposite Electric Charges, 2020, M.Sc
  • Synthesis of a Labeled Peptide and Study its Supramolecular Binding to p-Sulfonatocalix[4]arene and Curcumin Molecules, 2019, M.Sc
  • Modified Mart-1 peptide for binding to HLA-A*0201 on MCF7 cells, 2019, M.Sc
  • Synthesis and Dynamic Evaluation of Supper Flexible Peptides, 2018, M.Sc
  • Comparative Study of MOG with Cuprizon in EAE Mice Model, 2017, M.Sc

Positions and Projects

2004 M.Sc. Thesis: Preparation & characterization of structural and catalytical properties of immobilized acetylcholinesterase. (Department of biochemistry and biophysics, Babol University of medical sciences, Babol/Iran)

2008, Internship:

  • Chemically synthesis peptide silaffin R5 for biomineralization and imaging of silica particles and eGFP expression in E.Coli. (TUM-Munich, Germany)

2009, Researcher:

  • Studying scorpion’s toxin effect on metabolism and histology of Balb-C mice. (Pasteur Institute of Iran)

2010, PhD Thesis (Two Main Projects):

  1. Indicator Displacement Assays in Live Cells.
  2. Polypeptide Dynamics and Structure Studies Simultaneously by Collision-induced Fluorescence Quenching and Resonance Energy Transfer in the 10-Å Domain.

(Jacobs University Bremen, Germany)

2015, Researcher (at NIGEB):

  • Technology development for semi-industrial synthesis and US-pharmacopeia trial of Leuprolide acetate, a peptide-based drug.
  • Design and synthesis of novel oligopeptide-based drugs against tumor antigens

2017, Faculty member at NIGEB

  • Synthesis and Study Biological Function of Blood-brain Barrier Penetrating Peptides
  • Evaluating the Binding Affinity of the Labeled Peptides to HLA-A2 
  • Design and Synthesis of Novel Cyclic Cell-penetrating Peptides
  • Pharmacopeia Trial of Leuprolide Acetate
  • Supervising EU Pharmacopeia Tests on Growth Hormone