QUALIFICATIONS

BSc (Chemistry)

Mashhad University, Iran

1989

MSc (Organic Chemistry)

Mashhad University, Iran

1992

PhD (Bio-organic Chemistry)

Otago University, New Zealand

1998

Sabbatical Research

Chem Eng Dept. of Waterloo Un. Canada

2007-2008

Visiting Professor

Chem Eng Dept. of Waterloo Un. Canada

Nov. 2012

Visiting Professor

Plant Ecophysiol Dept, Paris-Sud Un.

Sep-Oct 2018

Visiting Professor

Plant Ecophysiol Dept, Paris-Saclay Un.

Sep-Oct 2019

Visiting Professor

Dept. Pharmaceutical Biology, Christian-Albrecht University, Kiel, Germany

Sep. to Dec. 2021

AWARDS

MSc scholarship

1989

The Ministry of Culture and Higher Education

PhD scholarship

1992

The Ministry of Culture and Higher Education

NSERC Grant (Canada)

2007

In collaboration with Professor R.L. Legge

DAAD Grant (Germany)

2012

In collaboration with Professor D. Schlosser

Paris-SUD Un. Grant

2018

In collaboration with Professor J. Ghashghaie

Paris-Saclay Un. Grant

2019

In coll. with Prof. J. Ghashghaie & Dr. Zoran G. Cerovic

DAAD Grant

2021

In collaboration with Professor C. Zidorn

WORKSHOPS

POSITIONS

2009 -20011

Head of Basic Sciences of Biotechnology Research Group (NIGEB)

2011 - 2013

Director of Evaluation, Budget, and Planning Office (NIGEB)

2012 - 2014

Head of Microbial Biotechnology Group (University of Science and Technology of Mazandaran)

2014 - 2018

Head of Plant Bioproducts Group (NIGEB)

2018 - 2020

Head of Agricultural Biotechnology Department (NIGEB)

2023 up to now

Manager of the International Office for Scientific Collaborations (NIGEB)

 1-3 March 2016, NIGEB, Tehran, IRAN

Head of Scientific Committee of 1st Congress of Chemical Biotechnology

AFFILIATIONS

•          Iranian Biotechnology Society
•          Iranian Chemical Society
•          Editorial Board of the Journal of Biotechnology and Health Sciences
•          Editorial Board of the Journal of Environmental Studies of Persian Gulf
•          Editorial Board of Iranian Journal of Biotechnology
•          
•           

Research Projects

1

Primiphos methyl synthesis

Granted by the science branch of Jehad Daneshgahi-Mashhad University

1991

2

Synthesis of the novel heterocyclic system, pyrimido [4,5-d] [1,2,3] triazine

MSc thesis (Scholarship)

1992

3

Kinetic and spectroscopic studies on cresolase and catecholase activities of tyrosinase

PhD thesis (Scholarship)

1998

4

Comparative study on Laboratory Scale Production of Shikonin by Arnebia euchroma, Lithospermum officinale and Lithospermum erythrorhizon in suspension Culture.

NRCGEB

2003

5

Examining the effect of shikonin on Helicobacter Pilori growth and proliferation

Ministry of Culture and Higher Education

2004

6

Production and purification of cholesterol oxidase from Nocardia Erythropolis (rhodococcus erythropolis ATCC 4277) and proper assay of its activity

Ministry of Culture and Higher Education

2005

7

Examining the biotransformation of phenolic substrates to ortho-dihydroxy compounds by the trapped tyrosinase into the solid phase

NRCGEB

2005

8

Measuring phenolic substances in the drinking water underground resources of Tehran by enzymatic and chemical methods.

Organization for Protection of Environment

2007

9

New applications for diazo derivatives of catechol

Presidential Office for Supporting Researchers (INSF)

2008

10

Designing selective inhibitors for tyrosinase

NIGEB

2008

11

Novel Diazo Cross-linkers

Natural Sci. and Eng. Res. Council

(NSERC) – Canada

2008

12

Surveying the Biochemical and Biophysical properties of the Arnebia euchroma Peroxidase

NIGEB

2009

13

Studying the anti-inflammatory effect of shikonin on microgelial cells

NIGEB

2010

14

Purification, biochemical characterization  and hemagglutinin activity of Agaricus bisporus Lectin

NIGEB

2010

15

Examining the organogenesis ability of the medicinal plant, Arnebia euchroma, callus

NIGEB

2011

16

Co-immobilization of tyrosinase and laccase in Cross-Linked Poly acrylamide using One Phase Binary Solutions as the reaction medium

German Academic Exchange Service

(DAAD)

2012

Research Projects (continue)

17

Examination of phenol removal methods from drinking water resources

Organization for Protection of Environment

2012

18

Identifying the phenolic pollutants in the drinking water resources of Tehran

Organization for Protection of Environment

2012

19

Enzymatic production of L-dopa; pre-pilot research

the Iran National Science Foundation (INSF)

2015

20

Study of indirect regeneration of Arnebia pulchra

NIGEB

2015

21

Synthesis of a novel class of chromophoric cross-linkers

University of Waterloo, ON-Canada

2016

22

Comparative evaluation of the antioxidant capacity of the extracts of callus and natural root of Arnebia euchroma

NIGEB

2016

23

Synthesis and preparation of advanced nano and mesoporous xerogels for enzyme immobilization and pollutant adsorption

ICRP

24

Reviewing analytical methods for measuring the concentration of total aromatic compounds in water resources

Tehran Water and Waste waters management

2017

25

Comparative study on the production of phenolic metabolites in the callus of Alkanna frigida and its natural root

NIGEB

2018

26

Non-destructive fluorescence-based method for monitoring the development of phenolic compounds in the solid cell culture of medicinal plants

Joint Research with the University of Paris-SUD

2018-2019

27

Evaluation of capabilities of phenolic compounds of Onosma dasytrichum and Alkanna frigida for UVA absorption and tyrosinase inhibition

NIGEB

2019

28

Extraction of phenolic acids with polyphenolase inhibition and UVA extinction capabilities from Rosa damascene waste

INSF

2019

29

Controlled release of plant aroma from hydrogel

Ministry of Science and Technology

2020

30

The fate of alkaloids in the cell culture of two medicinal plants of Boraginaceae;

Lithospermum officinale and Nonea caspica

DAAD + NIGEB

2021

Publications (1)

1

J. Org. Chem.

63, 4503-4505, (1998)

K. Haghbeen, Eng Wui Tan

Facile Synthesis of Catechol Azo Dyes

2

Anal. Biochem.,

312 23-32 (2003)

K. Haghbeen*, Eng Wue Tan

Direct Spectrophotometric Assay of Mono-oxygenase and Oxidase Activities of Mushroom Tyrosinase in the Presence of Synthetic and Natural Substrates

3

Coll. Surf. B; Biointerfaces,

32, 137-143 (2003)

F. Karbassi, K. Haghbeen A. A. Saboury, B. Ranjbarb, A. A. Moosavi-Movahedia

Activity, Structural and Stability Changes of Mushroom Tyrosinase by Sodium Dodecyl Sulfate

4

BBRC.

314 925-930 (2004).

Shahrzad Shareefi Brojerdi, K. Haghbeen*,

Successful resonance Raman study of cresolase activity of mushroom tyrosinase 

5

Biologia, Bratislava,

59/3: 317-324, (2004)

F. Karbassi, K. Haghbeen, A.A. Saboury

Calorimetric, spectrophotometric and circular dichroism studies on the impact of sodium dodecyl sulfate on the mushroom tyrosinase structure

6

Intl J Biol Macromol

34: 257–262, (2004)

A.A. Saboury, F. Karbassi, K. Haghbeen, B. Ranjbar,

A.A. Moosavi-Movahedi,

Stability, structural and suicide inactivation changes of Mushroom tyrosinase after acetylation by N-acetyl imidazole

7

BBA - Gen. Subjects 1675/1-3 139-146, (2004)

K. Haghbeen*, Ali Akbar Saboury, Farhad Karbassi

Substrate share in the suicide inactivation of mushroom tyrosinase

8

Iranian J Biotechnol,

2(3) 189-194, (2004) 

K. Haghbeen*, S. Shareefi Borojerdi, F. Rastgar

Purification of Tyrosinase from edible mushroom

9

Iranian Polymer J.

14(8) 729-734. (2005)

R. Agharafeie, K. Haghbeen*, M. Maghsudi

Polyacrylamide ability for protein immobilizing in one-phase binary-solvent systems

10

Coll. Surf. B: Biointerfaces 45 104–107. (2005)

N. Gheibi, A.A. Saboury, K. Haghbeen, A.A. Moosavi-Movahedi

Activity and structural changes of mushroom tyrosinase induced by n-alkyl sulfates

11

Intl J Biol Macromol.

36 305-309. (2005)

A. A. Saboury, M.S. Atri,M. H. Sanati, A.A. Moosavi-Movahedi, K. Haghbeen

Effects of calcium binding on the structure and stability of human growth hormone

12

J Enz Inh Med Chem. 20(4) 393-399. (2005)

N. Gheibi, A.A. Saboury, H. Mansuri-Torshizi, K. Haghbeen*, A.A. Moosavi

The inhibition effect of some n-alkyl dithiocarbamates on mushroom tyrosinase

13

Biologia Bratislava

20(4) 393-399 (2006)

Lithospermum officinale callus produces shikalkin

14

J Enz Inh Med Chem. 21(6), 711-717 (2006)

A. A. Saboury, S. Zolghadri, K. Haghbeen, A. A. Moosavi-Movahedi

The inhibitory effect of benzenethiol on the cresolase and catecholase activities of mushroom tyrosinase.

15

J Biosci.

31 (3), 355-362 (2006).

N. Gheibi, A.A. Saboury, K. Haghbeen, A. A. Moosavi-Movahedi

The effect of some osmolytes on the activity and stability of mushroom tyrosinase

16

Bull Korean Chem Soc.

27 (5), 642-648 (2006)

N. Gheibi, A.A. Saboury, K. Haghbeen

Substrate Construes the Copper and Nickel Ions Impacts on the Mushroom Tyrosinase Activities

17

J Enz Inh Med Chem. 22(2), 239-246 (2007)

M. Alijanianzadeh, A.A. Saboury, H. Mansuri-Torshizi, K. Haghbeen,

The Inhibitory effect of some new synthesized xanthates on mushroom tyrosinase activities

18

Modern Genetics Journal, 2(2), 2007, 41-51.

Sheikhani R., Mousavi A., Jonoubi P., Haghbeen K.

Analysis of T1 generation of 5-enol pyruvylshikmate-3-phosphate synthase (EPSPS) transformed oil seed rape plants for glyphosate resistance

Publications (2)

19

Dyes and Pigments

77, 363-368 (2008)

S. Rouhani , S. Salimi, K. Haghbeen

Development of optical pH sensors based on derivatives of hydroxyazobenzene, and the extended linear dynamic range using mixture of dyes

20

Spectrochimica Acta Part A

70(1) 1–6 (2008)

M. Shamsipur, B. Maddah, K. Haghbeen

Multiwavelength spectrophotometric determination of acidity constants of some azo dyes

21

Biotechnology,

(ANSI) 7(2); 200-204 (2008)

K. Rahimi, K. Haghbeen, J. Marefatjo, F. Rastgar Jazii

Successful production of hairy root of Valeriana sisymbriifolium by Agrobacterium rhizogenes

22

Iranian Polymer J

17 (5), 2008, 345-352

N. Bahmanyar, K. Haghbeen*, A. Jamshidi,

H. Mobedi

Studying the Structural Stability of Leuprolide acetate after Releasing from Lactide-co-Glycolide Copolymer by Different Spectroscopic Methods and HPTLC

23

J. Biol. Sci (ANSI),

8(3), 526-533, 2008

F. Saeid Nematpour, K. Haghbeen,

The Banana Pulp Polyphenol Oxidase Is a Tyrosinase

24

Chem. Engin. J. 

2009, 150, 1-7.

K. Haghbeen, R.. L. Legge

Adsorption of Phenolic Compounds on Some Hybrid Xerogels

25

J. Enz. Inh. and Med. Chem.

24(5), 1076-1081 (2009)

N. Gheibi‌, A.A. Saboury‌, K. Haghbeen, F. Rajaei‌, A.A. Pahlevan‌

Dual effects of aliphatic carboxylic acids on cresolase and catecholase reactions of mushroom tyrosinase

26

Iranian J. of Biology,

22(2), 2009, 300-311

Alizadeh M., Sabouni F., Abbasi AH., Moghimi A., Haghbeen K.

Effects of shikonin, a component of Chinese herbal medicine, on activation and apoptosis of inflammated microglial cells in vitro

27

Spectrochimica Acta Part A

74 (2009) 691–694

K. Alizadeh, S. Seyyedi, K. Haghbeen

Solvatochromism and temperature effects on the electronic absorption

spectra of some azo dyes

28

Interl J Biotechnol & Biochem (IJBB) 5, 4 (2009) 423—431.

J. Raheb, H. Esmaeil Lashgarian, Babak  K. Haghbeen,

Identification of Novel Cholesterol Oxidase from Rhodococcus Erythropolis ATCC 4277

29

J. Food Biochem.

2010, 34(2) 308-327

K. haghbeen^,* F. Saeid Nematpour, M. Babaei,

Surveying allosteric cooperativity and cooperative inhibition in mushroom tyrosinase

30

J. Biomed. Biotech. 2011, doi:10.1155/2011/165852

K. Haghbeen,* S. Pourmolaei, M. J.Mareftjo,  A.Mousavi, K. Akbari

Detailed Investigations on the Solid Cell Culture and Antimicrobial Activities of the Iranian Arnebia euchroma

31

Analytical Chemistry,

2011. 83(11), 4200-4205.

S.M. Moshtaghioun, K. Haghbeen

Direct Spectrophotometric Assay of Laccase Using Diazo Derivatives of Guaiacol,

32

Biotechnol Applied Biochem 2011, 58(6):456-63. doi: 10.1002/bab.42.

S. Farhadi, K. Haghbeen*, M.J. Marefatjo, M. Ghiyami Hoor

Anionic Peroxidase Production by Arnebia euchroma Callus

33

Intl Res J Applied & Basic Sci 2011, 392-397.pd

S. Bageri, F. Sanjarian, K. Haghbeen, M. Ali Ebrahimi

Establishment of cell suspension culture from onosma dasytrichum seed Callus culture

34

Biochem Eng J.

60, 2012, 99-105.

E. Jahangiria, R. Agharafeiea, K. Haghbeen*

Medium engineering to enhance mushroom tyrosinase stability

35

Iranian J. Biol,

2012 (1391), 25(3); 358-365.

Mirrazavi M., Sabouni F., Abbasi AH., Haghbeen K., Hajhosseini R. Nazem H.

The investigation of cytotoxic effects of standard shikonin andextraction shikonin from Arnebia euchroma on astrocytes

Publications (3)

36

Biochem Genet.

2012, 50(9-10):722-35. doi: 10.1007/s10528-012-9515-3

S. Babashpour, S. Aminzadeh, N. Farrokhi,

A. Karkhane, K. Haghbeen

Characterization of a Chitinase (Chit62) from Serratia marcescens B4A and Its Efficacy as a Bioshield Against Plant Fungal Pathogens

37

Iranian Journal of Horticaltural Sciences, 43(4), 403-410, 2013

N. zaynali , M. Delshad , A. kashi , K. Haghbin

Effect of Water Stress on Yield and Fruit Quality of some Iranian Melons

38

J of Aquatic Ecology,

2013, 2(3), 1-13

Akbarzadeh A, Farahmand H, Mahjoubi F, Nematollahi M A, Haghbeen K, Kolangi Miandareh H.

Selection of suitable reference genes for real-time PCR studies of early developmental stages of sturgeons

39

AAPS PharmSciTech

2013, 14(1):160-7. doi: 10.1208/s12249-012-9899-8

M. Alemi, F. Sabouni, F. Sanjarian, K. Haghbeen, S. Ansari

Anti-inflammatory Effect of Seeds and Callus of Nigella sativa L. Extracts on Mix

Glial Cells with Regard to Their Thymoquinone Content

40

progress in biological sciences

3(1) 2013, 53-59

A. Ahmadizadeh; F. Sanjarian; K. Haghbeen

Enzymatic detoxification of Don in transgenic plants via expression of Fusarium graminearum Tri101 gene

40

Appl Biochem Biotechnol. 2013, 169(3):773-85. doi: 10.1007/s12010-012-0014-0

M. Hosseini, A.A. Karkhane, B. Yakhchali, M. Shamsara, K. Haghbeen

In Silico and Experimental Characterization of Chimeric

Bacillus thermocatenulatus Lipase with the Complete

Conserved Pentapeptide of Candida rugosa Lipase

41

Marine and Freshwater Behaviour and Physiology, 2013, 45( 5) 349–355,

A. Akbarzadeh, K. Haghbeen*, H. Farahmand,

The time course of L-gulono-gamma-lactone oxidase expression during the larval ontogeny

42

Acta Biochem Biophys Sinica,  2013 45:10 845-856.

S. Matroodi, M. Zamani, K. Haghbeen*

Physicochemical Study of a Novel Chimeric Chitinase with Enhanced Binding Ability

43

Biotechnol Appl Biochem. 2014 Mar-Apr;61(2):118-25. doi: 10.1002/bab.1140.

Mojallali L, Shahbani Zahiri H, Rajaei S, Akbari Noghabi K, Haghbeen K.

A novel ∼34-kDa α-amylase from psychrotroph Exiguobacterium sp. SH3: production, purification, and characterization

43

Env Stu Persian Gulf,

2014, 1(2), 93-101)

A. Zaribafan, K. Haghbeen*

Spectrophotometric method for hydrogen peroxide determination through oxidation of organic dyes

44

Heterocycl. Commun.

2014; 20(6): 339–341

S. Rezaeian, M. Rahimizadeh, H. Eshghi*, K. Haghbin

Synthesis of the new heterocyclic system 7,8-dihydro-6H-benzotetrazolothiadiazine and

derivatives

45

Tetrahedron,

(2015) 71(3), 436-444

H. Eshghi, F. Moeinpour, S. Rezaeian, M. Bakavoli, M. Teymouri, A. Rostami, K. Haghbeen

Nanomagnetic organic-inorganic hybrid (Fe@Si-Gu-Prs): a novel magnetically green catalyst for the synthesis of tetrahydropyridine derivatives at room temperature under solvent-free conditions

46

Iran J Basic Med Sci,

18( 2) 2015, 122-129

N. Gheibi, N. Taherkhani, A. Ahmadi, K. Haghbeen, D. Ilghari

Characterization of inhibitory effects of the potential therapeutic inhibitors, benzoic acid and pyridine derivatives, on the monophenolase and diphenolase activities of tyrosinase

47

Iran J Biotech.

2015;13(4): e1058

P. Arghavani, K. Haghbeen*, A. Mousavi

Enhancement of Shikalkin Production in Arnebia euchroma Callus by a Fungal Elicitor, Rhizoctonia solani

Publications (4)

48

Canadian J. Chem. Eng.

 DOI: 10.1002/cjce.22341

2015, 93(12) 2214–2221

S. Hassani, A. Ghasemi, M. Fazli, K. Haghbeen,* R. L. Legge

Cation-assisted Adsorption of Chlorophenols by Nanoxerogels

49

J Applied Chem.

2015, 9 (33), 35-50

DOI: 10.22075/CHEM.2017.689

M. Shamsodin, M. Fazli, K. Haghbeen

Removal of Strontium (II) from aqueous solution by adsorption using Xerogel synthesized from TEOS: Batch and Fixed-bed Study

50

J Nanostructures,

5 (2015) 209-218

F. Bourumand Sarand, S. Hassani, M. Fazli, K. Haghbeen^*

Nanoporous Xerogel for Adsorption of Pb²⁺ and Cd²⁺

51

J. Med. Plants and By-products, JMPB 2015, 4(2), 233-242

T.Ezati, M.J. Marefatjo, K. Haghbeen^*,R. Ahmmadkhaniha

Successful indirect regeneration of Arnebia pulchra (Roemer and Schultes)

52

Iran. J. Chem. Chem. Eng.

34(4) 2015, 89-96

Darroudi, A.; Eshghi, H.; Rezaeian, S.; Chamsaz, M.; Bakavoli, M.; Haghbeen, K.

A Novel Carbon Paste Electrode

for Potentiometric Determination of Vanadyl Ion

53

NSMSI,

34(4) 2016, 31-43

M. Shamsodin; M. Fazli; M. Nasiri; K. Haghbeen

Removal of Strontium (II) from Aqueous Solution by Adsorption Using Xerogel Synthesized by TEOS: Kinetics and Thermodynamics Study

54

J. Food Biochem.

DOI: 10.1111/jfbc.12199

2016, 40(1) 100–108

S. Javadian, F. Sabouni, K. Haghbeen*

Origanum vulgare l. Extracts versus thymol: an Anti-inflammatory study on activated microglial And mixed glial cells

55

J. Enz Inhib. Med. Chem.

2016; 31(6):1162-9. doi: 10.3109/14756366.2015.1103234

F. Mirazizi, A. Bahrami, K. Haghbeen^*, M. Bakavoli, H. Shahbani Zahiri R. L. Legge

Rapid and direct spectrophotometric method for kinetics

studies and routine assay of peroxidase based on aniline diazo substrates

56

J. Plant Process and Function.

2016; 5 (16) :105-116

Zeinali N, Haghbeen K, Delshad M.

Water deficit effects on some physiological characteristics, sugars and proline as osmolytes in Cucumis melo var. reticulates cv. Samsoury.

57

J IRAN CHEM SOC

(2016) 13: 957.

doi:10.1007/s13738-016-0811-4

K. Haghbeen*,

R L. Legge

Synthesis of a novel class of chromophoric cross‑linkers

58

Separation Sci. Technol.

(2016) 51, 9,

DOI:10.1080/01496395.2016.1165251

M. Nadimifara, H. khorshidia, K. Haghbeena*, A.A. Karkhanea

A Facile and Cost Effective Method for Simultaneous Preparation of Lectin and Tyrosinase from Edible Mushroom

Publications (5)

59

Brazil. J Microbiol.

2016, 47(4): 931–940

N. Aliabadi, S. Aminzadeh∗, A.A. Karkhane, K. Haghbeen

Thermostable Chitinase from Cohnella sp. A01: Isolation and Product Optimization

60

Eur. J. Med. Chem.

2016, 21;122:138-48. doi: 10.1016/j.ejmech.2016.06.013

S. Hassani, K. Haghbeen,* M. Fazli

Non-specific binding sites help to explain mixed inhibition in

mushroom tyrosinase activities

61

Applied Biochem. Microbiol.

2016, 52(3), 304–310

N. Gheibia, S. Hosseini Zavareh, G. R. Rezaei Behbahani, K. Haghbeen, M. Sirati-sabet, D. Ilgharid, and K. Goodarzvand Chegini

Comprehensive Kinetic and Structural Studies of Different Flavonoids Inhibiting Diphenolase Activity of Mushroom Tyrosinase

62

Trop. plant pathol.

2016, 41(6) 350–356

DOI: 10.1007/s40858-016-0103-7

A. Ataei, M. Zamani, M. Motallebi, K. Haghbeen

Increased antifungal activity of Chit42 from Trichoderma atroviride by addition of a chitin binding domain

63

3 Biotech.

2016, 6(2): 129.

doi:  10.1007/s13205-016-0441-7

N. Mohandesi, S.O. Ranaei Siadat, K. Haghbeen, A. Hesampour

Cloning and expression of Saccharomyces cerevisiae SUC2 gene in yeast platform and characterization of recombinant enzyme biochemical properties

64

Enz.  Microbial  Technol.

2017, 96,  14–22.

N.  Mohandesi,  K.  Haghbeen,∗  O.  Ranaei, S.S.  Arab,

S.  Hassani

Catalytic  efficiency  and  thermostability  improvement  of  Suc2 invertase  through  rational  site-directed  mutagenesis

65

J Functional Foods

2017, 30, 56–62

N. Zeinalipour, K. Haghbeen*, I. Tavassolian, A.A. Karkhane, J. Ghashghaie

Enhanced production of 3-methylthiopropionic ethyl ester in native Iranian Cucumis melo L. Group Dudaim under regulated deficit irrigation

66

Biocatal. Biotransfor.

(2017) 35(1), 1-10

S. M. Moshtaghioun, M. Dadkhah, K. Bahremandjo, K. Haghbeen*, S. Aminzadeh, R. L. Legge

Optimization of Simultaneous Production of Tyrosinase and Laccase by Neurospora crassa

67

J Applied Chem.

(2017) 12(42),167-180

Ali Aslrousta; K. haghbeen, A. Akbari, M. Fazli

Investigation of adsorption of Chromium and Copper ions on TEOS xerogel

68

J. Applied Chem. Res.,

(2017) 11(3), 84-96

K. Haghbeen,* S. Rezaeian, M. Bakavoli

A Synthetic Approach for Evaluation of Cytosinediazonium Susceptibility

69

PLOS ONE,

2017, 12(4): e0175013

F. Zebardast Roodi, S. Aminzadeh, N. Farrokhi, A.A. Karkhane, K. Haghbeen

Cohnella amylo pullulanases: Biochemical characterization of two recombinant thermophilic enzymes

70

J. Agri. Sci. Technol.

2018, 20 (2), 347-357

Amiri-nowdijeh, F. Fazelipour, K. Haghbeen, M. Taheri, M. Hosseini-Mazinani

Minor Olive Varieties ITom Iran with Promising Nutraceutical Properties

Publications (6)

71

International J. Environ. Sci Technol.

2018, 15(8): 1679-1686

F. Mirazizi, A. Bahrami, S. Soleimani Asl, A. Zaribafan, K. Haghbeen*, S. Aminzadeh

Evaluation of oxidative enzymes for efficient degradation of aniline and phenolic pollutants

72

Extremophiles,

2018, 22(2): 315-326

K. Khalili Ghadikolaei, J. Gharechahi, K. Haghbeen, K. Akbari Noghabi, G. Hosseini Salekdeh, H. Shahbani Zahiri

A cold-adapted endoglucanase from camel rumen with high catalytic activity at moderate and low temperatures: an anomaly of truly cold-adapted evolution in a mesophilic environment

73

J Iran Chem Soc.

2018, 15 (5), 1097-1106

A. Hashem Nia, S. Rezaeian, H. Eshghi, K. Haghbeen, M. Bakavoli, M. Ramezani

Synthesis and evaluation of apoptosis induction levels of carbamate-and thiocarbamate-functionalized multi-walled carbon nanotubes

74

International J Biol Macromol. 2018, 114, 821-829

S. Hassani, B. Gharechaei, S. Nikfard, M. Fazli, N. Gheibi, R. Hardré, R. L Legge, K. Haghbeen

New insight into the allosteric effect of L-tyrosine on mushroom tyrosinase during L-dopa production

75

International J Biol Macromol 2018, 116, 64-70

Z. Emruzi, S. Aminzadeh, A. Karkhane, J. Alikhajeh, K. Haghbeen, D. Gholami

Improving the thermostability of Serratia marcescens B4A chitinase via G191V site-directed mutagenesis

76

Ecotoxicology and environmental safety

2018, 164, 455-466

S. Shahryari, H. Shahbani Zahiri, K. Haghbeen, L. Adrian, K. Akbari Noghabi

High phenol degradation capacity of a newly characterized Acinetobacter sp. SA01: Bacterial cell viability and membrane impairment in respect to the phenol toxicity

77

Applied Biochem. Biotechnol., 2019,  187 (3), 744-752

E. Khosravi, A. Mousavi, M. Farhadpour, J. Ghashghaie, F. Ghanati, K. Haghbeen

Pyrrolizidine Alkaloids-Free Extract from the Cell Culture of Lithospermum officinale with High Antioxidant Capacity

78

J. Marine Sci. Technol.

2019, 18(2) ; 66-75

Nateghzadeh M., Matroodi S., Haghbeen K.

Comparative Antioxidant Activities and Polyphenolic Content of Marine actinomycetes from Deylam nearshore sediments

79

Heliyon

2019,5 (9), e02543

M Shafiei, F Afzali, AA Karkhane, SM Ebrahimi, K Haghbeen

Cohnella sp. A01 laccase: thermostable, detergent resistant, anti-environmental and industrial pollutants enzyme

80

International J. Farm Sci., 2020,10 (3and4), 98-103

ST Goojgi, A Mousavi, K Haghbeen, K Piri

Morphological changes of Hyoscyamus niger calli resulting from somaclonal variation using ISSR markers

81

Spectrochimica Acta Part A: Mol. Biomol. Spectroscopy 2020, 229, 117897

P Mohammadnejad, SS Asl, S Aminzadeh, K Haghbeen

A new sensitive spectrophotometric method for determination of saliva and blood glucose

82

Mol. Biol. Res. Commun.

2020, 9 (1), 23

S Yousefian, T Lohrasebi, M Farhadpour, K Haghbeen

Production of phenolic acids in hairy root cultures of medicinal plant Mentha spicata L. in response to elicitors

83

Plant Cell, Tissue and Organ Culture (PCTOC)

2020,142, 285-297

S Yousefian, T Lohrasebi, M Farhadpour, K Haghbeen

Effect of methyl jasmonate on phenolic acids accumulation and the expression profile of their biosynthesis-related genes in Mentha spicata hairy root cultures

Publications (7)

84

Curr Pharm Biotechnol.

2020, doi: 10.2174/1389201021666201104145439.

M Kheyrollah, F Sabouni, M Farhadpour, K Haghbeen

Neuroprotective effect of Lithospermum officinale callus extract on inflamed primary microglial cells

85

Msystems

2021, 6 (1), doi.org/10.1128/mSystems.01175-20

S Shahryari, M Talaee, K Haghbeen, L Adrian, H Vali, HS Zahiri,

New Provisional Function of OmpA from Acinetobacter sp. Strain SA01 Based on Environmental Challenges

86

Plant Cell, Tissue and Organ Culture (PCTOC),

2021, 146, 375–386

P Mohammadnejad, SS Asl, Z Rasoulian, S Aminzadeh, J Ghashghaie

A potent peroxidase from solid cell culture of Ocimum basilicum with high sensitivity for blood glucose determination

87

J Food Biochem,

2021,45 (11), e13949

N Ghorbanian, A Mousavi, MJ Marefatjoo, NS Ghofrani, T Lohrasebi, K. Haghbeen

Toward more specific inhibitor for Solanum tuberosum polyphenol oxidase through a structural insight into its activities and inhibition

88

International Journal of Biological Macromolecules,

2021, 187(30), 373-385

Z. K. Mazraeh Shahi, Z. Takalloo, J. Mohamadzadeh, R. H Sajedi, K. Haghbeen, S. Aminzadeh

Thermophilic iron containing type superoxide dismutase from Cohnella sp. A01

89

The protein journal,

2021, 40 (5), 689-698

NS Ghofrani, M Sheikhi, …, K. Haghbeen

New Insight into the Interactions of Arbutin with Mushroom Tyrosinase

90

J Environmental Science and Health, Part A,

2021, 56 (10), 1131-1137

Z Javaheri Safa, A Olya, M Zamani, M Motalebi, R Khalili, K Haghbeen

Biodegradation of cyanide to ammonia and carbon dioxide by an industrially valuable enzyme from the newly isolated Enterobacter zs

91

J Iranian Chemical Society,

2021,1-12

F Haghbeen, N Ghorbanian, G Hajatpour, …, H Eshghi, K Haghbeen

Introducing a potential lead structure for the synthesis of more specific inhibitors of tyrosinases and catechol oxidases

92

Iranian Journal of Genetics and Plant Breeding,

10(1): 39-46, 2021

Tavakoli M., Mousavi A.,and Haghbeen K.

Evaluation of somaclonal variation of Arnebia pulchra (Boraginaceae) calli versus seeds using ISSR Marker

93

Phytochemistry,

2022, 194, 113022

SS Asl, AA Karkhane, JZ Amirzakaria, KA Noghabi, J Ghashghaie

Structure and activity of a novel robust peroxidase from Alkanna frigida cell culture

94

Biotechnology Letters,

2022,1-8

ST Goojgi, M Tavakoli, K Haghbeen, A Mousavi, K Piri

A novel spray bioreactor for the proliferation of plant callus; Hyoscyamus niger and Arnebia pulchra

95

Scientific Reports

12 (1), 10301. 2022

S Mohammadi, H Tarrahimofrad, S Arjmand, J Zamani, K Haghbeen, ...

A Expression, characterization, and activity optimization of a novel cellulase from the thermophilic bacteria Cohnella sp. A01

96

Journal of Food Biochemistry

46 (10), e14279. 2022

N Taherkhani, A Hekmat, H Piri, K Haghbeen

Structural and inhibitory effects of fulvic and humic acids against tyrosinase

97

Applied Chemistry

17 (63), 151-164, 2022

F Mirazizi, M Bakavoli, K Haghbeen, M Ebrahimi

Influential parameters on the substrate selectivity of laccase and tyrosinase

98

Journal of Inflammatory Diseases

Volume 0, Issue 0 (5-2023)

N Taherkhani, A Hekmat, H Piri, K Haghbeen

Humic and Fulvic acids induced thermodynamic and structural instability of tyrosinase with antiproliferative effect on A375 melanoma cancer cell line

99

Biotechnology and Bioprocess Engineering

DOI 10.1007/s12257-023-0049-9. 2023

Reyhane Zamani, Sayyed Shahryar Rahpeyma

Enhancing the Thermostability of Cellulase from Clostridium

thermocellumvia Salt Bridge Interactions

100

Journal of Cleaner Production

406, 137126, 2023

M Golbabaie, A Khosronejad, AA Baharanchi, MJ Marefatjoo

Enzymatic remediation of water resources by a durable and potent peroxidase from the cell culture of Origanum vulgare

101

Sustainable Environmental Research

M Golbabaie, B Gharachei, F Mirazizi, AA Baharanchi, A Khosronejad, AA Karkhanie K Haghbeen

Efficient degradation of various recalcitrant azo dyes in aqueous medium by immobilized Origanum vulgare peroxidase

Books & Chapters

1 -

Biotechnological Production of Plant Secondary Metabolites,

Edited by Ilkay Erdogan Orhan

Translated to Persian,

Published by NIGEB in 2021

2 -

Benefits and challenges of olive biophenols: a perspective,

By H Rasouli, MH Mazinani*, K Haghbeen

In “Olives and Olive Oil in Health and Disease Prevention”, 489-503

3 -

Treatment and valorization of olive mill wastewater

By P Mohammadnejad, K Haghbeen*, H Rasouli

In “Olives and Olive Oil in Health and Disease Prevention”, 505-519

4 -

Laccases in the Context of Potentially Cooperating Enzymes

By K Haghbeen, D Schlossser

In “Laccases in Bioremediation and Waste Valorisation”, 79-114

Patents

1 -

The technology of in-vitro production of Arnebia euchroma root

2 -

Enzymatic production of L-dopa

International proceedings and presentations

1

A Facile Method For Synthesising Diazo Catechol Dyes Used As Chromophoric Substrates For Tyrosinase

K. Haghbeen*, E. W. Tan

Molecules For Future)
(University Of Otago, Dunedin 2-6 December 1996)

2

Mix-Cooperativity In The Mushroom Tyrosinase Activities

K. Haghbeen*, E. W. Tan

15th FAOBMB Symposium,
Perspectives Of Biochemistry And Molecular Biology In The 21 Century
(Beigin, China, October 21-24, 2000)

3

Preliminary Experiments On Cell Culture Of Iranian Arnebia Euchrom Root Seems Quite Promising

K. Haghbeen*, A. Meshkat, S. Poormolaee

First International Congress On Plant Metabolomics
(Wageningen, Netherlands, April 7-11, 2002)

4

Calorimetric Studies Reveal Inhibition of The Catecholase Reaction Of Mushroom Tyrosinase By The Nitrated Diazo Derivatives Of Catechol

K. Haghbeen*, B. Zamani

8th European Symposium On Thermal Analysis And Calorimetry
(Barcelona, Spain, August 25-29, 2002)

5

Efficient Competitive Inhibitor Lets Resonance Raman Studies On Cresolase Activity Of Mushroom Tyrosinase

B. Zamani, K. Haghbeen*, A.A. Sabouri

Biophysical Society (46th Annual Meeting, February 23-27)
Biophysical Journal,Vol 82No 1, Part2, 2134-Pos, (2002)

6

Kinetic Evidence For The Allostric Behaviour Of Mushroom Tyrosinase

F. Karbasi, K. Haghbeen*, A. A. Sabouri

Biophysical Society (46th Annual Meeting, February 23-27)
Biophysical Journal,Vol 82No 1, Part2, 2133-Pos, (2002).

7

Non-Enzymicide Substrate For The Catecholase Reaction Of Mushroom Tyrosinase

Farhad Karbassi¹, Kamahldin Haghbeen², Ali Akbar Saboury¹

Biophysical Journal, February 2003, Volume 84, Number 2, Part 2 Of 2 1692-Pos   Board # B64

2003

8

Inhibition Studies On The Catecholase Reaction Of Mushroom Tyrosinase Failed To Produce Normal Dixon Plots

K. Haghbeen¹, Ali Akbar Saboury², Bita Zamani², Ali Akbar Moosavi-Movahedi²

Biophysical Journal, February 2003, Volume 84, Number 2, Part 2 Of 2 1693-Pos.

9

Organogenesis Ability Of The Arnebia Euchroma Callus”
 

K. Haghbeen, K. Rahimi*,  S. A. Mohammadi, M. Valizadeh

Fifth International Plant Tissue Culture & Biotechnology Conference From At.
(Dhaka, Bangladesh, December 4- 6, 2004)

10

Rhodococcus : Multi-Purposes Micro-Organism
 

B. Nazari, K. Haghbeen*

10th International Congress For Culture Collections
(Tsukuba, Japan, October 10-15, 2004)

11

The Effects Of Copper And Nickel Ions On The Activity And Stability Of Mushroom Tyrosinase”
 

F. Karbasi*, N. Gheibi, A.A. Sabouri, K. Haghbeen

Biophysical Society (49th Annual Meeting, February 12-16) Biophysical Journal, (2005)

12

Novel Optical Ph Sensors Based On Catechol Azo Dye Derivatives

S. Rouhani*, S. Salimi, K. Haghbeen

International Conference Analytical Chemistry And Chemical Analysis, 12-18 Sep. 2005, Keiv, Ukraine

International proceedings and presentations (2)

13

Studying The Apoptosis-Inducing Activity Of Shikonin

F. Sabouni*, S.H. Abbasi, K. Haghbeen, S.Z. Bathaie

First ICBMB, Tehran, Iran, Sep. 11-15, 2005, Clinical Biochemistry, 38 (9), 2005, Abs. 90

14

Efficient Medium Engineering For Tyrosinase Durability

Haghbeen, K*.; Jahangeeri, E.

1th Nternational IUPAC Conference On Green Chemistry, Dresden, Germany, Sep. 10-15; 2006

15

Simple Reactions For Biomimic Purposes; Versatility of Imines As Chelating Ligands

Haghbeen, K.; Mansouri-Torshizi, H

1th Nternational IUPAC Conference On Green Chemistry, Dresden, Germany, Sep. 10-15; 2006

16

Genetic Analysis And Shikimate Assay Of Glyphosphate …

R. Sheikhani, A. Mossavi, P. Jonoubi, K. Haghbeen

11^th IUPAC International Congress Of Pesticide Chem., Kobe, Japan, 6-11 Aug 2006

17

Kinetic Studies Guide To Effective Administration of Tyrosinase Inhibitor

Kamahldin Haghbeen, Fatimah Saied Nematpour

BIT Life Sciences’ 7th Annual Congress Of
International Drug Discovery Science And Technology (IDDST) 2009, Shanghai·China

18

Interesting Results From The Preliminary Studies on The Optimization Of The Neurospora Crassa (FGSC

#321) Growth And Laccase Production

Seyed Mohammad Moshtaghioun,1,2 Kamahldin Haghbeen1

16th National And 4th International Conference Of Biology, Ferdowsi University Of Mashhad, Mashhad, Iran

14-16 September 2010

19

A Direct And Accurate Spectrophotometric Method For Assaying The Laccase

S.M. Moshtaghioun, K. Haghbeen

Oxizymes & 9^th International Symposium On Peroxidases

Leipzig-Germany

14-16 June 2010

20

Biochemical Characterization Of The Peroxidase Extracted From The Arnebia Euchroma Callus

S. Farhadi, K. Haghbeen

Oxizymes & 9^th International Symposium On Peroxidases

Leipzig-Germany

14-16 June 2010

21

Stability And Kinetics Parameters Of Mushroom Tyrosinase In One-Phase Binary Medium

E. Jahangiri, K. Haghbeen

Oxizymes & 9^th International Symposium On Peroxidases

Leipzig-Germany

14-16 June 2010

22

Interesting Results from the Preliminary Studies on the Optimization of the Neurospora crassa (FGSC#321) Growth and Laccase Production

S.M. Moshtaghioun, K. Haghbeen

16th National and 4th International Conference of Biology, Ferdowsi University of Mashhad, Iran 14-16 September 2010

23

Bioethics; Can scientists meet a global consensus?

K. Haghbeen^*, E. Karimi, F. Ahmadpour, R. Heidari, H. Khorshidi

2^nd International Congress of Bioethics; 5-7 Feb 2011, Tehran, Iran

24

Tyrosinase immobilization on the magnetized hybrid xerogels with controlable binding sites

B. Gharehchei, S. Nikfard, M. Baharloui, D. Schlosser, K. Haghbeen

Oxizyme 2014, Vienna

International proceedings and presentations (3)

25

Chemical oxidation versus enzymatic oxidation of azo dyes

F. Mirazi, A. Bahrami, K. Haghbeen

Oxizyme 2014, Vienna

26

Combining laccase and tyrosinase for the biodegradation of environmental micro-pollutants

E. Jahangiri, K. Haghbeen, D. Schlosser

Oxizyme 2014, Vienna

27

Callogenesis and organogenesis in medicinal plant; Lithospermum officinalis

E. Khosravi, K. Haghbeen, A. Mosavi, F. Ghanati

19th National & 7th International Congress of Biology (30-31 Aug 2016); Tabriz - Iran

28

Measuring antioxidant power of plant callus of Origanum Vulgare

F. Ghaseminsb, Z. Rasoulian, K. Haghbeen, M.J. Marefatjoo

First International Congress of Biotechnology, 24-26 May 2015, Tehran - Iran

29

Study on callus induction in plant of Nonea caspica

Z. rasoulian, F. ghaseminasab, K. haghbin, E. khosravi

First International Congress of Biotechnology, 24-26 May 2015, Tehran - Iran

30

Evaluation of catalase and peroxidase production in callus culture of medicinal plant lemon balm (Melissa officinalis L.)

S, Soleimany, E. Khosravi, K. Haghbeen

First International Congress of Biotechnology, 24-26 May 2015, Tehran - Iran

31

Second International Congress of Biotechnology 2018

32

Adverse effect of latitude on phenolic acids and alkaloids biosynthesis in Lithospermum officinale

E. Khosravi, K. Haghbeen, A. Mosavi

Х lnternational Scientific Agriculture Symposium, AGROSYM 2019" 03- 06 Oct. Jahorina mountain,  Bosnia and Herzegovina

Teaching experiences

Undergraduate Courses

   Postgraduate Courses

1 - General Chemistry (I),

2 - General Chemistry (II),

3 - Analytical Chemistry,

4 - Organic Chemistry (I),

5 - Organic Chemistry (II),

6 - Organic Chemistry (III),

7 - Biochemistry (Basic),

8 - Environmental Chemistry,

9 - Principle of Organic Synthesis,

10 - Physical Organic Chemistry,

11 - Separation and Identification of Organic Compounds,

12 - Applications of Spectroscopic Methods

   13 - Biochemistry (Advanced),

   14 - Cellular Biophysics,

   15 - Transport phenomena in living organisms,

   16 - Biochemical and Biophysical Methods in Bioscience,

   17 - Applied Enzymology

Supervised research theses 

* National Research Institute for Genetic Engineering and Biotechnology (NIGEB)

** Science and Research Unit of Azad University (SRU-AU)

*** Iran University of science and Technology (IUST)

**** Islamic Azad University (IAU)

***** Payam Noor University (PNU)

***** Chemistry & Chem Eng Res Center of Iran (CCERCI)

***** Institute of Biochemistry & Biophysics (IBB)

1

Shikonin production by selected cell-lines of Iranian Arnebia euchroma (A. Meshkat)- SRU-AU

MSc

March 2002

2

Spectroscopic and calorimetric examination of inhibition of oxidase activity of tyrosinase (B. Zamani) – Birjand Un.

MSc

March 2002

3

Biosynthesis pathway of shikalkin in Arnebia euchroma

(S. Pourmolaei) - SRU-AU

MSc

Jan. 2003

4

Purification and assessment of tyrosinase from edible mushroom (S. Sharifi) - SRU-AU

MSc

Jan. 2003

5

Study on rosmarinic acid production by the Lithospermum officinale callus (E. Pourazizi) - SRU-AU

MSc

July 2003

6

Biosynthetic pathway of shikalkin in the Lithospermum officinale root (F. Ghafarri) - SRU-AU

MSc

2004

7

Thermodynamic of Agaricus bisporus tyrosinase activities

(F. Karbasi) – IBB, Tehran Un.

PhD

July 2004

8

Molecular & biochemical aspects of cholesterol oxidase production in Rhodococcus erythropolis ATCC4277 – (B. Nazari) – Tehran Un.

MSc

Sep

2004

9

Evalution of enzymatic activity of Arnebia euchroma callus for biotransformations (M. Ghiami Hoor)- IUST

MSc

May

2005

10

PEGylation technology consideration on Bovine Serum Albumin (E. Mobedi) CCERCI.

MSc

June

2005

11

Tyrosinase efficiency enhancement through immobilization on solid phase (R. Agharafeie) – IUST

MSc

April

2005

12

Examining the effects of some metal ions and synthetic ligands on the activity and active structure of mushroom tyrosinase – (N. Gheibi) – IBB, Tehran of Un.

PhD

2005

13

Agrobacterium effect on the Arnebia euchroma callus

(K. Rahimi)- Tabriz Un.

MSc

May 2005

Supervised research theses (2)

14

Extraction and purification of Neurospora crassa tyrosinase

(M. Babaei Khalili) – Guillan Un.

MSc

Feb

2006

15

The effect of thiophenol on the activity of tyrosinase (S. Zolghadri-Jahromi) – IBB - Tehran of Un.

MSc

Sep

2006

16

Study on mushroom tyrosinase inhibition by new synthetic ligands (M. Alijanzadeh) – IBB, Tehran Un.

MSc

Feb

2007

17

Functional stability of mushroom tyrosinase in medium containing water and acetonitrile (E. Jahangeeri) - PNU

MSc

March

2007

18

Study on active site of mushroom tyrosinase in secondary and tertiary structures (R. Khoshneviszadeh). IAU

MSc

19

Study on Banana tyrosinase and its role in enzymatic browning (F.S. Nematpour) SRU-AU

PhD

Feb. 2008

20

Leuprolide acetate stability study in formulations by different spectroscopic methods - (N. Bahmanyar) – IAU

MSc

2006

21

Effects of shikonin on activation and apoptosis of inflamed microglial cells in vitro - (M. Alizade) – Mashhad Un.

MSc

Sep

2007

22

Electrophoretic pattern of cytoplasmic proteins of Agaricus bisporus (A. Ansariyan) SRU-AU

MSc

Feb. 2010

23

Extraction and purification of peroxidase from Arnebia euchroma callus (S. Farhadi) SRU-AU

MSc

Feb. 2010

24

Expression of acetyltransferase gene in tobacco (A. Ahmadizadeh) – NIGEB

MSc

Dec. 2010

25

The antioxidant ability of Arnebia euchroma callus in comparison with its natural root -  (N. Amin Tehrani) – PNU

MSc

Sep

2010

26

Antioxidant activity of the Lithospermum Officinalis callus

(F. Fazelipour) - PNU

MSc

Sep

2010

27

Adsorption of heavy metal ions on xerogels

(F. Broumand) – Semnan Un.

MSc

Sep

2010

28

Studying the Tyrosinase production in Neurospora crassa –

(M. Dadkhah) – PNU

MSc

Feb

2011

Supervised research theses (3)

29

Surveying the function and stability of laccases enzyme in non conventional media  (K. Bahremandjooy) – PNU

MSc

2011

30

Simultaneous production of laccase and tyrosinase by Neurospora crassa (M. Moshtaghioun) - NIGEB

PhD

2011

31

Investigation of adsorption effect of metal ions Cd, Zn and Ni on TEOS & TMOS Xerogels (M. Safarpour) – Semnan Un.

MSc

Aug

2011

32

Investigation of adsorption of Chromium & Copper ions on TEOS & TMOS xerogels (M. Naserelami) – Semnan Un.

MSc

Oct

2011

33

Callus production from Nigella sativa L.  Seeds and study of anti-inflammatory effects of the extracted oli from seed and callus on Rat brain mix cells - (M. Alemi) – NIGEB.

MSc

Sep

2011

34

Ontogeny of L-gulonolactone oxidase enzyme gene expression in Persion sturgeon, Acipenser persicus (A. Akbarzadeh) TehranUn.

Ph.D

Sep

2011

35

Surveying drought stress on melons (N. Zeinali)- Tehran Un.

PhD

Feb

2012

36

Assisted adsorption of Metal ions on TEOS xerogel by oxalic acid

(E. Kianejad) – Semnan Un.

MSc

Feb

2012

37

Investigation of adsorption metal ions Cd²⁺ and Ni²⁺ on Alominum

(S. Sadeghian) – Semnan Un.

MSc

Sep

2012

38

Hairy roots induction in Arnebia euchroma by Agrobacterium rhizogenesis (T. Ezati) – NIGEB

MSc

Feb

2012

39

Surveying the Inhibition of the Cresolase and Catecholase Activities of Tyrosinase at low concentrations of Kojic acid , 2-ketohexanoic acid and pyruvic acid - (Y. Tahmasebi) – NIGEB

MSc

Sep

2012

40

Evaluation of the efficiency of phenols and aromatic compounds removal from drinking water resources by advanced oxidation and enzymatic processes - (A. Zaribafan) – Shahid Chamran Un.

MSc

Feb

2012

41

Extraction and purification of lectin from the edible button mushroom (Agaricus bisporus ) and evaluation of its hemagglutinin activity in the presence of ABO blood groups cells – (H. Khorshidi) -  NIGEB

MSc

Feb

2012

42

Investigation of adsorption effect of Chlorophenol pollutants on TEOS & TMOS Xerogels in the presence of metal ions - (A. Ghasemi) – Semnan Un.

MSc

Sep

2012

Supervised research theses (4)

43

Induction and growth of Onosma dasytrichum callus (S. Bagheri) – PNU

MSc

Aug. 2012

44

Study on Organogenesis Ability of the Arnebia euchroma Callus (M.J. Marefatjoo) - IAU

MSc

Aug.

2012

45

Investigation of adsorption organic pigments on TEOS Xerogel absorbent – (A. Mohebbi) – Semnan Un.

MSc

Oct

2012

46

Adsorption of metal cations on ormosils of TMOS 

(A. Zarghami) – Semnan Un.

MSc

Sep

2013

47

Examining the kinetic and Thermodynamic stability of the immobilized mushroom tyrosinase on the modified xerogels

(B. Gharehchei) – Semnan Un.

MSc

March

2013

48

Study the kinetic of L-dopa production by free and immobilized mushroom tyrosinase (S. Nikfard Zakelebari) – Semnan Un.

MSc

March

2013

49

Examining the adsorption and desorption of bi-valent metal cation (Cu(II)) on the ormosils derivatized from teraethoxy-ortho-silane - ( N.Shakarami)- Semnan Un.

MSc

Sep

2013

50

Studying the interaction of Lectin and Tyrosinases of edible mushroom Agaricus bisporus - (M. S. Nadimi far) NIGEB

MSc

March

 2014

51

Studying Shikalkin production by the callus of Iranian Arnebia euchroma in the presence of Methyl jasmonate , Salicylic acid and Rhizoctonia solani as elicitors - (P. Arghavani) NIGEB

MSc

Feb

2014

52

Determination of optimum condition for Origanum vulgare callus induction and study of anti-inflammatory effects of plant extract on rat brain mix glial cell culture (S. Javadian) IAU.

MSc

Jan. 2013

53

Degradation of diazo dyes by Neurospora crassa laccase (A. Bahrami) IUST

MSc

Nov. 2013

54

Surveying Influential Parameters on the Production invertase by saccharomyces cerevisiae(M. Ghasemi) – Semnan Un.

MSc

March

2015

56

Study on in vitro optimization of Arnebia euchoma root proliferation and its pigment production (F. Ghaseminasab) PNU

PhD

Feb

2015

57

Examination of antioxidant capacity of Nonea caspica and Melissa officinalis Calli - (Z. Rsoulian) – PNU

Msc

Aug

2015

Supervised research theses (5)

58

Functionalization of multi-wall cabon nanotube and their biological evaluation Synthesis of new heterocyclic system7,8-dihydro-6H benzotetrazolo thiadiazines and derivatives Synthesis of substituted tetrahydropyridine with novel catalyst preyssler heteropolyacid supported on the surface of nano magnetic silica Synthesis of new derivatives  of benzo[g]pteridine

(Sh. Rezaeian) – Mashhad Un.

PhD

March

2015

59

Evaluation of the surface hydrophobicity of the porous polymers on the concentration of alkyphenols in aqueous medium - (M. Baharlouie Yancheshmeh) – IAU.

MSc

Feb

2016

60

Evaluation of polyphenoloc contents and antioxidant activity in cell suspention cultures and optimization of genomic DNA and RNA extractions in Lithospermum officinale L. (N. Faridi) NIGEB

MSc

March  2016

61

Cloning and expression of Invertase – coding gene in Pichin pastoris and biochemical characterization of the enzyme using rational mutagenesis (N. Mohandesi) NIGEB.

PhD

Oct.

2016

62

Enzymatic oxidation of diazo dyes (F. Mirazizi) – Mashhad Un.

PhD

Aug

2016

63

Study of apple (Malus domestica Borkh.) tyrosinase inhibition by som of biological componds - (S. Kompanisaeid) – Kharazmi Un.

MSc

Sep

2016

64

Inhibition of mushrrom tyrosinase by carboxylic acids

(S. Hassani) - Semnan University

PhD

Aug 2016

65

Diversity of Gene Clusters for Polyketide in actinomycetes (M. Nateghzadeh) – Khoramshahr Marine Science University

MSc

Jan 2017

66

Flavonoids production in Nonea caspica callus

(A. Hamzepour) - PNU

MSc

Aug 2017

67

Activities of Oxidoreductases during proliferation of Lithospermum officinale callus (N. Soltani) - NIGEB

MSc

Feb 2017

68

PPO activity and phenolic metabolites production in Onosma dasytrichum callus (M. Sheikhi) - NIGEB

MSc

Feb 2017

69

Effects of Lithospermum officinale callus extract on activation and apoptosis of inflammated microglial cells in vitro – (M. Kheyrollah) - Esfahan Un.

MSc

Sep 2017

Supervised research theses (7)

70

Evaluation of inhibition of polyphenol oxidase in potato plant (Solanom tuberosum)

(N. Ghorbanian) - NIGEB

MSc 

March 2018

71

Investigation on peroxidase performance from ocimum Bassilicum`s calluse for detection of cholesterol and Glucose in natural samples

(P. Mohammadnejad) - NIGEB

MSc 

Feb 2018

72

Competetive biosynthetic routes of phenolic acids in medicinal plants “Lithospermum officinale and Onosma dasytrichum”

(S. Nezami) - NIGEB

 MSc

Feb 2019

73

Investigation of the effective factors on callus propagation  and expression of some key genes  during cell cycle of medicinal plant; Lithospermum officinale L. (E. Khosravi) - SRU-AU

PhD

Aug 2018

74

Computational Analysis of  strong inhibitors of mushroom tyrosinase at low and high concentrations in the presence of p-coumaric acid (S. Shamaie) - NIGEB

MSc

Aug 2019

75

Production of neurospora crassa tyrosinase by gene expression in E. coli and evaluation of enzyme activity (G. Hajatpour) - NIGEB

MSc

Aug 2019

76

Effect of methyl jasmonate on phenolic acids accumulation and the expression profile of their biosynthesis-related genes in Mentha spicata hairy root cultures (E. Yousefian) - SRU-AU

PhD

Aug

2020

77

Function of OmpA from Acinetobacter sp. Strain SA01 Based on Environmental Challenges (E. Shahriyari) - SRU-AU

PhD

Feb

2021

78

Study of peroxidase isozyme in Alkanna frigida (S. Soleimani Asl) - NIGEB

PhD

Sep 2021

79

Investigation on feeding strategy of the influential nutrients for propagation of Arnebia pulchra cells in a spray bioreactor (M. Tavakoli) - NIGEB

PhD

Sep 2022

80

Optimization of total alkaloids production in Papaver orientale callus (S. Tahmasbi) - NIGEB

PhD

Sep 2022

81

Physicochemical studies on peroxidase of Origanum vulgare callus with emphasize on potential environmental applications for removal of phenolic pollutants (M. Golbabaei) - NIGEB

PhD

Sep 2023