National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P Q R S T V W Y
*     2                                        
-     366                                        
?                                              
A     15                                   2    
C     21   1     2                              
D     22                                        
E 1   18                 1                      
F     24         2                              
G     15                                        
H     12             1                          
I     30               2                        
K 1   15                                        
L     30                               1        
M     3                                        
N     6                                        
P     21                         1              
Q 2   18             1                          
R     12               1                        
S     27                   1                    
T     15               1                        
V     36                   1                    
W     3                   1                    
Y     21   1         2                          

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Czech_Republic 27894 A 601 601
1 Czech_Republic 27895 T 601 601
2 Czech_Republic 27896 G 601 601
3 Czech_Republic 27897 A 601 601
4 Czech_Republic 27898 A 601 601
5 Czech_Republic 27899 A 601 601
6 Czech_Republic 27900 T 601 601
7 Czech_Republic 27901 T 601 601
8 Czech_Republic 27902 T 601 601
9 Czech_Republic 27903 C 601 601
10 Czech_Republic 27904 T 601 601
11 Czech_Republic 27905 T 601 601
12 Czech_Republic 27906 G 601 601
13 Czech_Republic 27907 T 601 601
14 Czech_Republic 27908 T 601 601
15 Czech_Republic 27909 T 601 601
16 Czech_Republic 27910 T 601 601
17 Czech_Republic 27911 C 601 601
18 Czech_Republic 27912 T 601 601
19 Czech_Republic 27913 T 601 601
20 Czech_Republic 27914 A 601 601
21 Czech_Republic 27915 G 601 601
22 Czech_Republic 27916 G 601 601
23 Czech_Republic 27917 A 601 601
24 Czech_Republic 27918 A 601 601
25 Czech_Republic 27919 T 601 601
26 Czech_Republic 27920 C T 601 599 Ile9Ile
27 Czech_Republic 27921 A 601 601
28 Czech_Republic 27922 T 601 601
29 Czech_Republic 27923 C 601 601
30 Czech_Republic 27924 A 601 601
31 Czech_Republic 27925 C T 601 600 Thr11Ile
32 Czech_Republic 27926 A 601 601
33 Czech_Republic 27927 A 601 601
34 Czech_Republic 27928 C 601 601
35 Czech_Republic 27929 T 601 601
36 Czech_Republic 27930 G 601 601
37 Czech_Republic 27931 T 601 601
38 Czech_Republic 27932 A 601 601
39 Czech_Republic 27933 G 601 601
40 Czech_Republic 27934 C 601 601
41 Czech_Republic 27935 T 601 601
42 Czech_Republic 27936 G 601 601
43 Czech_Republic 27937 C 601 601
44 Czech_Republic 27938 A 601 601
45 Czech_Republic 27939 T 601 601
46 Czech_Republic 27940 T 601 601
47 Czech_Republic 27941 T 601 601
48 Czech_Republic 27942 C 601 601
49 Czech_Republic 27943 A 601 601
50 Czech_Republic 27944 C T 601 597 His17His
51 Czech_Republic 27945 C T 601 600 Gln18*
52 Czech_Republic 27946 A 601 601
53 Czech_Republic 27947 A 601 601
54 Czech_Republic 27948 G 601 601
55 Czech_Republic 27949 A 601 601
56 Czech_Republic 27950 A 601 601
57 Czech_Republic 27951 T 601 601
58 Czech_Republic 27952 G 601 601
59 Czech_Republic 27953 T 601 601
60 Czech_Republic 27954 A 601 601
61 Czech_Republic 27955 G 601 601
62 Czech_Republic 27956 T 601 601
63 Czech_Republic 27957 T 601 601
64 Czech_Republic 27958 T 601 601
65 Czech_Republic 27959 A 601 601
66 Czech_Republic 27960 C 601 601
67 Czech_Republic 27961 A 601 601
68 Czech_Republic 27962 G 601 601
69 Czech_Republic 27963 T 601 601
70 Czech_Republic 27964 C 601 601
71 Czech_Republic 27965 A 601 601
72 Czech_Republic 27966 T 601 601
73 Czech_Republic 27967 G 601 601
74 Czech_Republic 27968 T C 601 600 Cys25Cys
75 Czech_Republic 27969 A 601 601
76 Czech_Republic 27970 C 601 601
77 Czech_Republic 27971 T 601 601
78 Czech_Republic 27972 C T 601 589 Gln27*
79 Czech_Republic 27973 A 601 601
80 Czech_Republic 27974 A 601 601
81 Czech_Republic 27975 C 601 601
82 Czech_Republic 27976 A 601 601
83 Czech_Republic 27977 T 601 601
84 Czech_Republic 27978 C 601 601
85 Czech_Republic 27979 A 601 601
86 Czech_Republic 27980 A 601 601
87 Czech_Republic 27981 C 601 601
88 Czech_Republic 27982 C 601 601
89 Czech_Republic 27983 A 601 601
90 Czech_Republic 27984 T C 601 600 Tyr31His
91 Czech_Republic 27985 A 601 601
92 Czech_Republic 27986 T 601 601
93 Czech_Republic 27987 G 601 601
94 Czech_Republic 27988 T 601 601
95 Czech_Republic 27989 A 601 601
96 Czech_Republic 27990 G 601 601
97 Czech_Republic 27991 T 601 601
98 Czech_Republic 27992 T 601 601
99 Czech_Republic 27993 G 601 601
100 Czech_Republic 27994 A 601 601
101 Czech_Republic 27995 T 601 601
102 Czech_Republic 27996 G 601 601
103 Czech_Republic 27997 A 601 601
104 Czech_Republic 27998 C 601 601
105 Czech_Republic 27999 C 601 601
106 Czech_Republic 28000 C 601 601
107 Czech_Republic 28001 G A 601 599 Pro36Pro
108 Czech_Republic 28002 T 601 601
109 Czech_Republic 28003 G 600 600
110 Czech_Republic 28004 T 600 600
111 Czech_Republic 28005 C 600 600
112 Czech_Republic 28006 C 600 600
113 Czech_Republic 28007 T 600 600
114 Czech_Republic 28008 A 600 600
115 Czech_Republic 28009 T 600 600
116 Czech_Republic 28010 T C 600 599 Ile39Ile
117 Czech_Republic 28011 C 600 600
118 Czech_Republic 28012 A 600 600
119 Czech_Republic 28013 C 600 600
120 Czech_Republic 28014 T 600 600
121 Czech_Republic 28015 T 600 600
122 Czech_Republic 28016 C 600 600
123 Czech_Republic 28017 T 600 600
124 Czech_Republic 28018 A 600 600
125 Czech_Republic 28019 T 600 600
126 Czech_Republic 28020 T 600 600
127 Czech_Republic 28021 C 600 600
128 Czech_Republic 28022 T 600 600
129 Czech_Republic 28023 A 600 600
130 Czech_Republic 28024 A 600 600
131 Czech_Republic 28025 A 600 600
132 Czech_Republic 28026 T 600 600
133 Czech_Republic 28027 G T 600 599 Trp45Leu
134 Czech_Republic 28028 G 600 600
135 Czech_Republic 28029 T 600 600
136 Czech_Republic 28030 A 600 600
137 Czech_Republic 28031 T 600 600
138 Czech_Republic 28032 A 600 600
139 Czech_Republic 28033 T 600 600
140 Czech_Republic 28034 T 600 600
141 Czech_Republic 28035 A 600 600
142 Czech_Republic 28036 G 600 600
143 Czech_Republic 28037 A 600 600
144 Czech_Republic 28038 G 600 600
145 Czech_Republic 28039 T 600 600
146 Czech_Republic 28040 A 600 600
147 Czech_Republic 28041 G 600 600
148 Czech_Republic 28042 G 600 600
149 Czech_Republic 28043 A 600 600
150 Czech_Republic 28044 G 600 600
151 Czech_Republic 28045 C T 600 597 Ala51Val
152 Czech_Republic 28046 T 600 600
153 Czech_Republic 28047 A 600 600
154 Czech_Republic 28048 G T 600 588 Arg52Ile
155 Czech_Republic 28049 A 600 600
156 Czech_Republic 28050 A 600 600
157 Czech_Republic 28051 A 600 600
158 Czech_Republic 28052 A 600 600
159 Czech_Republic 28053 T 600 600
160 Czech_Republic 28054 C T 600 598 Ser54Leu
161 Czech_Republic 28055 A 600 600
162 Czech_Republic 28056 G 600 600
163 Czech_Republic 28057 C 600 600
164 Czech_Republic 28058 A 600 600
165 Czech_Republic 28059 C 600 600
166 Czech_Republic 28060 C 600 600
167 Czech_Republic 28061 T 600 600
168 Czech_Republic 28062 T 600 600
169 Czech_Republic 28063 T 600 600
170 Czech_Republic 28064 A 600 600
171 Czech_Republic 28065 A 600 600
172 Czech_Republic 28066 T 600 600
173 Czech_Republic 28067 T 600 600
174 Czech_Republic 28068 G 600 600
175 Czech_Republic 28069 A 600 600
176 Czech_Republic 28070 A 600 600
177 Czech_Republic 28071 T 600 600
178 Czech_Republic 28072 T 600 600
179 Czech_Republic 28073 G 600 600
180 Czech_Republic 28074 T 600 600
181 Czech_Republic 28075 G 600 600
182 Czech_Republic 28076 C 600 600
183 Czech_Republic 28077 G T 600 599 Val62Leu
184 Czech_Republic 28078 T 600 600
185 Czech_Republic 28079 G 600 600
186 Czech_Republic 28080 G 600 600
187 Czech_Republic 28081 A 600 600
188 Czech_Republic 28082 T 600 600
189 Czech_Republic 28083 G 600 600
190 Czech_Republic 28084 A 600 600
191 Czech_Republic 28085 G 600 600
192 Czech_Republic 28086 G 600 600
193 Czech_Republic 28087 C T 600 599 Ala65Val
194 Czech_Republic 28088 T 600 600
195 Czech_Republic 28089 G 600 600
196 Czech_Republic 28090 G 600 600
197 Czech_Republic 28091 T 600 600
198 Czech_Republic 28092 T 600 600
199 Czech_Republic 28093 C 600 599
200 Czech_Republic 28094 T 600 600
201 Czech_Republic 28095 A T 600 589 Lys68*
202 Czech_Republic 28096 A 600 600
203 Czech_Republic 28097 A 600 600
204 Czech_Republic 28098 T 600 600
205 Czech_Republic 28099 C 600 600
206 Czech_Republic 28100 A 600 600
207 Czech_Republic 28101 C 600 600
208 Czech_Republic 28102 C 600 600
209 Czech_Republic 28103 C 600 600
210 Czech_Republic 28104 A 600 600
211 Czech_Republic 28105 T 600 600
212 Czech_Republic 28106 T 600 600
213 Czech_Republic 28107 C 600 600
214 Czech_Republic 28108 A 600 600
215 Czech_Republic 28109 G T 600 599 Gln72His
216 Czech_Republic 28110 T C 600 599 Tyr73His
217 Czech_Republic 28111 A G 600 588 Tyr73Cys
218 Czech_Republic 28112 C 600 600
219 Czech_Republic 28113 A 600 600
220 Czech_Republic 28114 T 600 600
221 Czech_Republic 28115 C 600 600
222 Czech_Republic 28116 G 600 600
223 Czech_Republic 28117 A 600 600
224 Czech_Republic 28118 T 600 600
225 Czech_Republic 28119 A 600 600
226 Czech_Republic 28120 T 600 600
227 Czech_Republic 28121 C 600 600
228 Czech_Republic 28122 G 600 600
229 Czech_Republic 28123 G 600 600
230 Czech_Republic 28124 T 600 600
231 Czech_Republic 28125 A 600 600
232 Czech_Republic 28126 A 600 600
233 Czech_Republic 28127 T 600 600
234 Czech_Republic 28128 T 600 600
235 Czech_Republic 28129 A 600 600
236 Czech_Republic 28130 T 600 600
237 Czech_Republic 28131 A 600 600
238 Czech_Republic 28132 C 600 600
239 Czech_Republic 28133 A 600 600
240 Czech_Republic 28134 G 600 600
241 Czech_Republic 28135 T 600 600
242 Czech_Republic 28136 T 600 600
243 Czech_Republic 28137 T 600 600
244 Czech_Republic 28138 C 600 600
245 Czech_Republic 28139 C 600 600
246 Czech_Republic 28140 T 600 600
247 Czech_Republic 28141 G T 600 598 Cys83Phe
248 Czech_Republic 28142 T 600 600
249 Czech_Republic 28143 T 600 600
250 Czech_Republic 28144 T C 600 598 Leu84Ser
251 Czech_Republic 28145 A 600 600
252 Czech_Republic 28146 C 600 600
253 Czech_Republic 28147 C 600 600
254 Czech_Republic 28148 T 600 600
255 Czech_Republic 28149 T 600 600
256 Czech_Republic 28150 T 600 600
257 Czech_Republic 28151 T 600 600
258 Czech_Republic 28152 A 600 600
259 Czech_Republic 28153 C 600 600
260 Czech_Republic 28154 A 600 600
261 Czech_Republic 28155 A 600 600
262 Czech_Republic 28156 T 600 600
263 Czech_Republic 28157 T 600 600
264 Czech_Republic 28158 A 600 600
265 Czech_Republic 28159 A 600 600
266 Czech_Republic 28160 T 600 600
267 Czech_Republic 28161 T 600 600
268 Czech_Republic 28162 G 600 600
269 Czech_Republic 28163 C 600 600
270 Czech_Republic 28164 C 600 600
271 Czech_Republic 28165 A 600 600
272 Czech_Republic 28166 G 600 600
273 Czech_Republic 28167 G A 600 599 Glu92Lys
274 Czech_Republic 28168 A 600 600
275 Czech_Republic 28169 A 600 600
276 Czech_Republic 28170 C 600 600
277 Czech_Republic 28171 C 600 600
278 Czech_Republic 28172 T 600 600
279 Czech_Republic 28173 A 600 600
280 Czech_Republic 28174 A 600 600
281 Czech_Republic 28175 A 600 600
282 Czech_Republic 28176 T 600 600
283 Czech_Republic 28177 T 600 600
284 Czech_Republic 28178 G 600 600
285 Czech_Republic 28179 G 600 600
286 Czech_Republic 28180 G 600 600
287 Czech_Republic 28181 T 600 600
288 Czech_Republic 28182 A 600 600
289 Czech_Republic 28183 G 600 600
290 Czech_Republic 28184 T 600 600
291 Czech_Republic 28185 C 600 600
292 Czech_Republic 28186 T 600 600
293 Czech_Republic 28187 T 600 600
294 Czech_Republic 28188 G 600 600
295 Czech_Republic 28189 T 600 600
296 Czech_Republic 28190 A 600 600
297 Czech_Republic 28191 G 600 600
298 Czech_Republic 28192 T 600 600
299 Czech_Republic 28193 G 600 600
300 Czech_Republic 28194 C 600 600
301 Czech_Republic 28195 G 600 600
302 Czech_Republic 28196 T 600 600
303 Czech_Republic 28197 T 600 600
304 Czech_Republic 28198 G T 600 597 Cys102Phe
305 Czech_Republic 28199 T 600 600
306 Czech_Republic 28200 T 600 600
307 Czech_Republic 28201 C 600 600
308 Czech_Republic 28202 G 600 600
309 Czech_Republic 28203 T 600 600
310 Czech_Republic 28204 T 600 600
311 Czech_Republic 28205 C 600 600
312 Czech_Republic 28206 T 600 600
313 Czech_Republic 28207 A 600 600
314 Czech_Republic 28208 T 600 600
315 Czech_Republic 28209 G T 600 594 Glu106*
316 Czech_Republic 28210 A 600 600
317 Czech_Republic 28211 A 600 600
318 Czech_Republic 28212 G 600 600
319 Czech_Republic 28213 A 600 600
320 Czech_Republic 28214 C 600 599
321 Czech_Republic 28215 T 601 600
322 Czech_Republic 28216 T 601 601
323 Czech_Republic 28217 T C 601 600 Phe108Phe
324 Czech_Republic 28218 T 601 601
325 Czech_Republic 28219 T 601 601
326 Czech_Republic 28220 A 601 601
327 Czech_Republic 28221 G 601 601
328 Czech_Republic 28222 A 601 601
329 Czech_Republic 28223 G 601 601
330 Czech_Republic 28224 T 601 601
331 Czech_Republic 28225 A 601 601
332 Czech_Republic 28226 T 601 601
333 Czech_Republic 28227 C 601 601
334 Czech_Republic 28228 A 601 601
335 Czech_Republic 28229 T 601 601
336 Czech_Republic 28230 G 601 601
337 Czech_Republic 28231 A 601 601
338 Czech_Republic 28232 C 601 601
339 Czech_Republic 28233 G 601 601
340 Czech_Republic 28234 T 601 601
341 Czech_Republic 28235 T 601 601
342 Czech_Republic 28236 C 601 601
343 Czech_Republic 28237 G 601 601
344 Czech_Republic 28238 T 601 601
345 Czech_Republic 28239 G 601 601
346 Czech_Republic 28240 T 601 601
347 Czech_Republic 28241 T 601 601
348 Czech_Republic 28242 G 601 601
349 Czech_Republic 28243 T 601 601
350 Czech_Republic 28244 T 601 601
351 Czech_Republic 28245 T 601 601
352 Czech_Republic 28246 T 601 601
353 Czech_Republic 28247 A 601 601
354 Czech_Republic 28248 G 601 601
355 Czech_Republic 28249 A 601 601
356 Czech_Republic 28250 T 601 601
357 Czech_Republic 28251 T 601 601
358 Czech_Republic 28252 T 601 601
359 Czech_Republic 28253 C T 601 599 Phe120Phe
360 Czech_Republic 28254 A 601 601
361 Czech_Republic 28255 T 601 601
362 Czech_Republic 28256 C 601 601
363 Czech_Republic 28257 T 601 601
364 Czech_Republic 28258 A 601 601
365 Czech_Republic 28259 A 601 601