National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P Q R S T V W Y
*     2                                        
-     366                                        
?                                              
A     15                                        
C     21                                        
D     22     1                                  
E     18                                        
F     24         2         1               1    
G     15   1                               1    
H     12                                        
I     30               1   1             1      
K     15                                        
L     30                               1        
M     3                                        
N     6                                        
P     21                   2         1 1        
Q 1   18                   1                    
R     12               1                        
S     27         1         1                    
T     15 1             1                        
V     36 1                 1               1    
W     3                                        
Y     21             3                          

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Chile 27894 A 963 963
1 Chile 27895 T 963 963
2 Chile 27896 G 963 963
3 Chile 27897 A 963 963
4 Chile 27898 A 963 963
5 Chile 27899 A 963 963
6 Chile 27900 T C 963 957 Phe3Leu
7 Chile 27901 T 963 963
8 Chile 27902 T 963 963
9 Chile 27903 C 963 963
10 Chile 27904 T 963 963
11 Chile 27905 T 963 963
12 Chile 27906 G 963 963
13 Chile 27907 T 963 963
14 Chile 27908 T 963 963
15 Chile 27909 T 963 963
16 Chile 27910 T 963 963
17 Chile 27911 C T 963 962 Phe6Phe
18 Chile 27912 T 963 963
19 Chile 27913 T 963 963
20 Chile 27914 A 963 963
21 Chile 27915 G 963 963
22 Chile 27916 G 963 963
23 Chile 27917 A 963 963
24 Chile 27918 A 963 963
25 Chile 27919 T C 963 962 Ile9Thr
26 Chile 27920 C 963 963
27 Chile 27921 A 963 963
28 Chile 27922 T 963 963
29 Chile 27923 C 963 963
30 Chile 27924 A 963 963
31 Chile 27925 C 963 963
32 Chile 27926 A 963 963
33 Chile 27927 A 963 963
34 Chile 27928 C 963 963
35 Chile 27929 T 963 963
36 Chile 27930 G 963 963
37 Chile 27931 T 963 963
38 Chile 27932 A 963 963
39 Chile 27933 G 963 963
40 Chile 27934 C 963 963
41 Chile 27935 T 963 963
42 Chile 27936 G 963 963
43 Chile 27937 C 963 963
44 Chile 27938 A 963 963
45 Chile 27939 T 963 963
46 Chile 27940 T 963 963
47 Chile 27941 T 963 963
48 Chile 27942 C 963 963
49 Chile 27943 A 963 963
50 Chile 27944 C 963 963
51 Chile 27945 C T 963 962 Gln18*
52 Chile 27946 A 963 963
53 Chile 27947 A 963 963
54 Chile 27948 G 963 963
55 Chile 27949 A 963 963
56 Chile 27950 A 963 963
57 Chile 27951 T 963 963
58 Chile 27952 G 963 963
59 Chile 27953 T 963 963
60 Chile 27954 A 963 963
61 Chile 27955 G 963 963
62 Chile 27956 T 963 963
63 Chile 27957 T 963 963
64 Chile 27958 T 963 963
65 Chile 27959 A 963 963
66 Chile 27960 C 963 963
67 Chile 27961 A 963 963
68 Chile 27962 G 963 963
69 Chile 27963 T 963 963
70 Chile 27964 C 963 963
71 Chile 27965 A 963 963
72 Chile 27966 T 963 963
73 Chile 27967 G 963 963
74 Chile 27968 T 963 963
75 Chile 27969 A 963 963
76 Chile 27970 C T 963 929 Thr26Ile
77 Chile 27971 T 963 963
78 Chile 27972 C 963 963
79 Chile 27973 A T 963 962 Gln27Leu
80 Chile 27974 A 963 963
81 Chile 27975 C 963 963
82 Chile 27976 A 963 963
83 Chile 27977 T 963 963
84 Chile 27978 C 963 963
85 Chile 27979 A 963 963
86 Chile 27980 A 963 963
87 Chile 27981 C 963 963
88 Chile 27982 C T,G 963 956 Pro30Leu-p.Pro30Arg
89 Chile 27983 A 963 963
90 Chile 27984 T C 963 962 Tyr31His
91 Chile 27985 A 963 963
92 Chile 27986 T 963 963
93 Chile 27987 G 963 963
94 Chile 27988 T 963 963
95 Chile 27989 A 963 963
96 Chile 27990 G 963 963
97 Chile 27991 T 963 963
98 Chile 27992 T 963 963
99 Chile 27993 G 963 963
100 Chile 27994 A 963 963
101 Chile 27995 T C 963 959 Asp34Asp
102 Chile 27996 G 963 963
103 Chile 27997 A 963 963
104 Chile 27998 C 963 963
105 Chile 27999 C 963 963
106 Chile 28000 C 963 963
107 Chile 28001 G 963 963
108 Chile 28002 T 963 963
109 Chile 28003 G 963 963
110 Chile 28004 T 963 963
111 Chile 28005 C T 963 961 Pro38Ser
112 Chile 28006 C 963 963
113 Chile 28007 T 963 963
114 Chile 28008 A 963 963
115 Chile 28009 T 963 963
116 Chile 28010 T 963 963
117 Chile 28011 C 963 963
118 Chile 28012 A 963 963
119 Chile 28013 C 963 963
120 Chile 28014 T 959 959
121 Chile 28015 T 959 959
122 Chile 28016 C 959 959
123 Chile 28017 T C 959 950 Tyr42His
124 Chile 28018 A 959 959
125 Chile 28019 T 959 959
126 Chile 28020 T 959 959
127 Chile 28021 C 959 959
128 Chile 28022 T 959 959
129 Chile 28023 A 959 959
130 Chile 28024 A 959 959
131 Chile 28025 A 959 959
132 Chile 28026 T 959 959
133 Chile 28027 G 959 959
134 Chile 28028 G 959 959
135 Chile 28029 T C 959 958 Tyr46His
136 Chile 28030 A 959 959
137 Chile 28031 T 959 959
138 Chile 28032 A 959 959
139 Chile 28033 T 959 959
140 Chile 28034 T 959 959
141 Chile 28035 A 959 959
142 Chile 28036 G 959 959
143 Chile 28037 A 959 959
144 Chile 28038 G 959 959
145 Chile 28039 T C 959 958 Val49Ala
146 Chile 28040 A 959 959
147 Chile 28041 G 959 959
148 Chile 28042 G 959 959
149 Chile 28043 A 959 959
150 Chile 28044 G 959 959
151 Chile 28045 C 959 959
152 Chile 28046 T 959 959
153 Chile 28047 A 959 959
154 Chile 28048 G T 959 958 Arg52Ile
155 Chile 28049 A 959 959
156 Chile 28050 A 959 959
157 Chile 28051 A 959 959
158 Chile 28052 A 959 959
159 Chile 28053 T 959 959
160 Chile 28054 C 959 959
161 Chile 28055 A 959 959
162 Chile 28056 G 959 959
163 Chile 28057 C 959 959
164 Chile 28058 A 959 959
165 Chile 28059 C 959 959
166 Chile 28060 C 959 959
167 Chile 28061 T 959 959
168 Chile 28062 T 959 959
169 Chile 28063 T 959 959
170 Chile 28064 A 959 959
171 Chile 28065 A 959 959
172 Chile 28066 T 959 959
173 Chile 28067 T 959 959
174 Chile 28068 G 959 959
175 Chile 28069 A 959 959
176 Chile 28070 A 959 959
177 Chile 28071 T 959 959
178 Chile 28072 T 959 959
179 Chile 28073 G 959 959
180 Chile 28074 T 963 963
181 Chile 28075 G 963 961
182 Chile 28076 C 963 963
183 Chile 28077 G 963 963
184 Chile 28078 T 963 963
185 Chile 28079 G T 963 962 Val62Val
186 Chile 28080 G 963 963
187 Chile 28081 A 963 963
188 Chile 28082 T 963 963
189 Chile 28083 G 963 963
190 Chile 28084 A 963 963
191 Chile 28085 G 963 963
192 Chile 28086 G 963 963
193 Chile 28087 C 963 962
194 Chile 28088 T 963 963
195 Chile 28089 G 963 963
196 Chile 28090 G T 963 962 Gly66Val
197 Chile 28091 T 963 963
198 Chile 28092 T 963 963
199 Chile 28093 C T 963 961 Ser67Phe
200 Chile 28094 T 963 963
201 Chile 28095 A 963 963
202 Chile 28096 A 963 963
203 Chile 28097 A 963 963
204 Chile 28098 T 963 963
205 Chile 28099 C 963 963
206 Chile 28100 A 963 963
207 Chile 28101 C 963 963
208 Chile 28102 C T 963 962 Pro70Leu
209 Chile 28103 C 963 963
210 Chile 28104 A 963 963
211 Chile 28105 T 965 965
212 Chile 28106 T 965 965
213 Chile 28107 C 965 965
214 Chile 28108 A 965 965
215 Chile 28109 G 965 965
216 Chile 28110 T 965 965
217 Chile 28111 A 965 965
218 Chile 28112 C 965 965
219 Chile 28113 A 965 965
220 Chile 28114 T 965 965
221 Chile 28115 C T 965 946 Ile74Ile
222 Chile 28116 G 965 965
223 Chile 28117 A 965 965
224 Chile 28118 T 965 965
225 Chile 28119 A 965 965
226 Chile 28120 T 965 965
227 Chile 28121 C 965 965
228 Chile 28122 G T 965 964 Gly77Cys
229 Chile 28123 G 965 965
230 Chile 28124 T 965 965
231 Chile 28125 A 965 965
232 Chile 28126 A 965 965
233 Chile 28127 T 965 965
234 Chile 28128 T 965 965
235 Chile 28129 A 965 965
236 Chile 28130 T 965 965
237 Chile 28131 A 965 965
238 Chile 28132 C 965 965
239 Chile 28133 A 965 965
240 Chile 28134 G 965 965
241 Chile 28135 T 965 965
242 Chile 28136 T 965 965
243 Chile 28137 T 965 965
244 Chile 28138 C 965 965
245 Chile 28139 C 965 965
246 Chile 28140 T 965 965
247 Chile 28141 G 965 965
248 Chile 28142 T 965 964
249 Chile 28143 T 965 965
250 Chile 28144 T C 965 945 Leu84Ser
251 Chile 28145 A 965 965
252 Chile 28146 C 964 964
253 Chile 28147 C 964 964
254 Chile 28148 T 964 964
255 Chile 28149 T 964 964
256 Chile 28150 T 964 964
257 Chile 28151 T 964 964
258 Chile 28152 A G 964 963 Thr87Ala
259 Chile 28153 C 964 964
260 Chile 28154 A 964 964
261 Chile 28155 A 964 964
262 Chile 28156 T 964 964
263 Chile 28157 T 964 964
264 Chile 28158 A 964 964
265 Chile 28159 A 964 964
266 Chile 28160 T 964 964
267 Chile 28161 T 964 964
268 Chile 28162 G 964 964
269 Chile 28163 C 964 964
270 Chile 28164 C 964 964
271 Chile 28165 A 964 964
272 Chile 28166 G 964 964
273 Chile 28167 G 964 964
274 Chile 28168 A 964 964
275 Chile 28169 A 964 964
276 Chile 28170 C 964 964
277 Chile 28171 C 964 964
278 Chile 28172 T 964 964
279 Chile 28173 A 963 963
280 Chile 28174 A 963 963
281 Chile 28175 A 963 963
282 Chile 28176 T 963 963
283 Chile 28177 T 963 963
284 Chile 28178 G 963 962
285 Chile 28179 G 963 963
286 Chile 28180 G 963 963
287 Chile 28181 T 963 963
288 Chile 28182 A 963 963
289 Chile 28183 G 963 963
290 Chile 28184 T 963 963
291 Chile 28185 C 963 963
292 Chile 28186 T 963 963
293 Chile 28187 T 963 963
294 Chile 28188 G T 963 960 Val99Leu
295 Chile 28189 T 963 963
296 Chile 28190 A 963 963
297 Chile 28191 G 963 963
298 Chile 28192 T 963 963
299 Chile 28193 G 963 963
300 Chile 28194 C 963 963
301 Chile 28195 G 963 963
302 Chile 28196 T 963 963
303 Chile 28197 T 963 963
304 Chile 28198 G 963 963
305 Chile 28199 T 963 963
306 Chile 28200 T 963 963
307 Chile 28201 C T 963 960 Ser103Leu
308 Chile 28202 G 963 963
309 Chile 28203 T 963 963
310 Chile 28204 T 963 963
311 Chile 28205 C 963 963
312 Chile 28206 T 963 963
313 Chile 28207 A 963 963
314 Chile 28208 T 963 963
315 Chile 28209 G 963 963
316 Chile 28210 A 963 963
317 Chile 28211 A 963 963
318 Chile 28212 G 963 963
319 Chile 28213 A 963 963
320 Chile 28214 C 963 963
321 Chile 28215 T 963 963
322 Chile 28216 T 963 963
323 Chile 28217 T 963 963
324 Chile 28218 T 963 963
325 Chile 28219 T 963 963
326 Chile 28220 A 963 963
327 Chile 28221 G 963 963
328 Chile 28222 A 963 963
329 Chile 28223 G 963 963
330 Chile 28224 T 963 963
331 Chile 28225 A 963 963
332 Chile 28226 T 963 963
333 Chile 28227 C 963 963
334 Chile 28228 A 963 963
335 Chile 28229 T 963 963
336 Chile 28230 G 963 962
337 Chile 28231 A 963 963
338 Chile 28232 C 963 963
339 Chile 28233 G 963 963
340 Chile 28234 T 963 963
341 Chile 28235 T 963 963
342 Chile 28236 C 963 963
343 Chile 28237 G 963 963
344 Chile 28238 T 963 963
345 Chile 28239 G 963 963
346 Chile 28240 T 963 963
347 Chile 28241 T 963 963
348 Chile 28242 G 963 963
349 Chile 28243 T 963 963
350 Chile 28244 T 963 963
351 Chile 28245 T 963 963
352 Chile 28246 T 963 963
353 Chile 28247 A 963 963
354 Chile 28248 G 963 963
355 Chile 28249 A 963 963
356 Chile 28250 T 963 963
357 Chile 28251 T G 963 962 Phe120Val
358 Chile 28252 T 963 963
359 Chile 28253 C T 963 962 Phe120Phe
360 Chile 28254 A C 963 962 Ile121Leu
361 Chile 28255 T 963 963
362 Chile 28256 C 963 963
363 Chile 28257 T 963 963
364 Chile 28258 A 963 963
365 Chile 28259 A 963 963