National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P Q R S T V Y
*     3                                      
-     370                                      
?                                            
A     27 1                               1 1  
C     18                                      
D     6     1                                
E     24     1 1                   1          
F     30                                      
G     12                                      
H     9                                      
I     25                                      
K     21                 2           1        
L     45         2                         1  
M     6                                      
N     6                                      
P     18                                      
Q     15                           1 1        
R     15               1                      
S     21                         1     1      
T     30               2                      
V     24         1     1                      
Y 1   15                                     1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Turkey 27394 A 485 485
1 Turkey 27395 T 485 485
2 Turkey 27396 G 485 485
3 Turkey 27397 A 485 485
4 Turkey 27398 A G 485 484 Lys2Arg
5 Turkey 27399 A 485 485
6 Turkey 27400 A 485 485
7 Turkey 27401 T 485 485
8 Turkey 27402 T 485 485
9 Turkey 27403 A 485 485
10 Turkey 27404 T 485 485
11 Turkey 27405 T 485 485
12 Turkey 27406 C 485 485
13 Turkey 27407 T 485 485
14 Turkey 27408 T 485 485
15 Turkey 27409 T 485 485
16 Turkey 27410 T 485 485
17 Turkey 27411 C 485 485
18 Turkey 27412 T 485 485
19 Turkey 27413 T 485 485
20 Turkey 27414 G 485 485
21 Turkey 27415 G A 485 483 Ala8Thr
22 Turkey 27416 C 485 485
23 Turkey 27417 A 485 485
24 Turkey 27418 C 485 485
25 Turkey 27419 T 485 485
26 Turkey 27420 G 485 485
27 Turkey 27421 A 485 485
28 Turkey 27422 T 485 485
29 Turkey 27423 A 485 485
30 Turkey 27424 A 485 485
31 Turkey 27425 C 485 485
32 Turkey 27426 A 485 485
33 Turkey 27427 C 485 485
34 Turkey 27428 T 485 485
35 Turkey 27429 C 485 485
36 Turkey 27430 G 485 485
37 Turkey 27431 C 485 485
38 Turkey 27432 T 485 485
39 Turkey 27433 A 485 485
40 Turkey 27434 C 485 485
41 Turkey 27435 T 485 485
42 Turkey 27436 T 485 485
43 Turkey 27437 G 485 485
44 Turkey 27438 T 485 485
45 Turkey 27439 G 485 485
46 Turkey 27440 A 486 485
47 Turkey 27441 G 486 485
48 Turkey 27442 C T 486 483 Leu17Phe
49 Turkey 27443 T 486 485
50 Turkey 27444 T 486 485
51 Turkey 27445 T 486 485
52 Turkey 27446 A 486 485
53 Turkey 27447 T 486 485
54 Turkey 27448 C 486 485
55 Turkey 27449 A 486 485
56 Turkey 27450 C 486 485
57 Turkey 27451 T 486 486
58 Turkey 27452 A 486 486
59 Turkey 27453 C 486 486
60 Turkey 27454 C 486 486
61 Turkey 27455 A 486 486
62 Turkey 27456 A 486 486
63 Turkey 27457 G 486 486
64 Turkey 27458 A 486 486
65 Turkey 27459 G 486 486
66 Turkey 27460 T 486 486
67 Turkey 27461 G 486 486
68 Turkey 27462 T 486 486
69 Turkey 27463 G A 486 485 Val24Ile
70 Turkey 27464 T 486 486
71 Turkey 27465 T 486 486
72 Turkey 27466 A 486 486
73 Turkey 27467 G 486 486
74 Turkey 27468 A 486 486
75 Turkey 27469 G 486 486
76 Turkey 27470 G 486 486
77 Turkey 27471 T 486 486
78 Turkey 27472 A 486 486
79 Turkey 27473 C 486 486
80 Turkey 27474 A 487 487
81 Turkey 27475 A 487 487
82 Turkey 27476 C T 487 484 Thr28Ile
83 Turkey 27477 A 487 487
84 Turkey 27478 G 487 487
85 Turkey 27479 T 487 487
86 Turkey 27480 A 487 487
87 Turkey 27481 C 487 487
88 Turkey 27482 T 487 487
89 Turkey 27483 T 487 487
90 Turkey 27484 T 487 487
91 Turkey 27485 T 487 487
92 Turkey 27486 A 485 484
93 Turkey 27487 A 485 484
94 Turkey 27488 A 485 485
95 Turkey 27489 A G 485 484 Lys32Lys
96 Turkey 27490 G 485 485
97 Turkey 27491 A 485 485
98 Turkey 27492 A 485 485
99 Turkey 27493 C 485 485
100 Turkey 27494 C 485 485
101 Turkey 27495 T 486 486
102 Turkey 27496 T 486 486
103 Turkey 27497 G 486 486
104 Turkey 27498 C 486 486
105 Turkey 27499 T 486 486
106 Turkey 27500 C 486 486
107 Turkey 27501 T 486 486
108 Turkey 27502 T 486 486
109 Turkey 27503 C 486 486
110 Turkey 27504 T 486 486
111 Turkey 27505 G 486 486
112 Turkey 27506 G 486 486
113 Turkey 27507 A 486 486
114 Turkey 27508 A 486 486
115 Turkey 27509 C T 486 485 Thr39Ile
116 Turkey 27510 A 486 486
117 Turkey 27511 T 486 486
118 Turkey 27512 A 486 486
119 Turkey 27513 C T 486 485 Tyr40Tyr
120 Turkey 27514 G 486 486
121 Turkey 27515 A 486 486
122 Turkey 27516 G 486 485
123 Turkey 27517 G 486 485
124 Turkey 27518 G 486 485
125 Turkey 27519 C 486 485
126 Turkey 27520 A 486 485
127 Turkey 27521 A 486 485
128 Turkey 27522 T 486 485
129 Turkey 27523 T 486 485
130 Turkey 27524 C 486 485
131 Turkey 27525 A 486 485
132 Turkey 27526 C 486 485
133 Turkey 27527 C 486 485
134 Turkey 27528 A 486 485
135 Turkey 27529 T 486 485
136 Turkey 27530 T 486 485
137 Turkey 27531 T 486 485
138 Turkey 27532 C 486 485
139 Turkey 27533 A 486 485
140 Turkey 27534 T 486 485
141 Turkey 27535 C 486 485
142 Turkey 27536 C 486 485
143 Turkey 27537 T 486 485
144 Turkey 27538 C G 486 484 Leu49Val
145 Turkey 27539 T 486 485
146 Turkey 27540 A 486 485
147 Turkey 27541 G 486 485
148 Turkey 27542 C 486 485
149 Turkey 27543 T 486 485
150 Turkey 27544 G 486 485
151 Turkey 27545 A 486 485
152 Turkey 27546 T 486 485
153 Turkey 27547 A 486 485
154 Turkey 27548 A 486 485
155 Turkey 27549 C 486 485
156 Turkey 27550 A 486 485
157 Turkey 27551 A 486 485
158 Turkey 27552 A G 486 483 Lys53Lys
159 Turkey 27553 T 486 485
160 Turkey 27554 T 486 485
161 Turkey 27555 T 486 485
162 Turkey 27556 G 486 485
163 Turkey 27557 C 486 485
164 Turkey 27558 A 486 485
165 Turkey 27559 C 486 485
166 Turkey 27560 T 486 485
167 Turkey 27561 G 486 485
168 Turkey 27562 A 486 485
169 Turkey 27563 C 486 485
170 Turkey 27564 T 486 485
171 Turkey 27565 T 486 485
172 Turkey 27566 G 486 485
173 Turkey 27567 C 486 485
174 Turkey 27568 T 486 485
175 Turkey 27569 T 486 485
176 Turkey 27570 T 486 485
177 Turkey 27571 A 486 486
178 Turkey 27572 G 487 487
179 Turkey 27573 C T 487 486 Ser60Ser
180 Turkey 27574 A 486 486
181 Turkey 27575 C 486 486
182 Turkey 27576 T 486 486
183 Turkey 27577 C 486 486
184 Turkey 27578 A 486 486
185 Turkey 27579 A G 486 484 Gln62Gln
186 Turkey 27580 T 486 486
187 Turkey 27581 T 486 486
188 Turkey 27582 T 486 486
189 Turkey 27583 G 486 486
190 Turkey 27584 C 486 486
191 Turkey 27585 T 486 486
192 Turkey 27586 T 486 486
193 Turkey 27587 T 486 486
194 Turkey 27588 T 486 486
195 Turkey 27589 G 486 486
196 Turkey 27590 C 486 486
197 Turkey 27591 T 486 486
198 Turkey 27592 T 486 486
199 Turkey 27593 G 486 486
200 Turkey 27594 T 486 486
201 Turkey 27595 C 487 486
202 Turkey 27596 C 487 486
203 Turkey 27597 T 487 487
204 Turkey 27598 G 487 487
205 Turkey 27599 A 487 487
206 Turkey 27600 C T 487 486 Asp69Asp
207 Turkey 27601 G 487 487
208 Turkey 27602 G 487 487
209 Turkey 27603 C 487 487
210 Turkey 27604 G 487 487
211 Turkey 27605 T 487 487
212 Turkey 27606 A 487 487
213 Turkey 27607 A 487 487
214 Turkey 27608 A 487 487
215 Turkey 27609 A 487 487
216 Turkey 27610 C 487 487
217 Turkey 27611 A 487 487
218 Turkey 27612 C 487 487
219 Turkey 27613 G 487 487
220 Turkey 27614 T 487 487
221 Turkey 27615 C 487 487
222 Turkey 27616 T 486 486
223 Turkey 27617 A 485 485
224 Turkey 27618 T 485 485
225 Turkey 27619 C 485 485
226 Turkey 27620 A 485 485
227 Turkey 27621 G 485 485
228 Turkey 27622 T 485 485
229 Turkey 27623 T 485 485
230 Turkey 27624 A 485 485
231 Turkey 27625 C 485 485
232 Turkey 27626 G 485 485
233 Turkey 27627 T 485 485
234 Turkey 27628 G 485 485
235 Turkey 27629 C 485 485
236 Turkey 27630 C 485 485
237 Turkey 27631 A 485 485
238 Turkey 27632 G 485 485
239 Turkey 27633 A 485 485
240 Turkey 27634 T C 486 485 Ser81Pro
241 Turkey 27635 C 486 486
242 Turkey 27636 A 486 486
243 Turkey 27637 G 486 486
244 Turkey 27638 T 486 486
245 Turkey 27639 T 486 486
246 Turkey 27640 T 486 486
247 Turkey 27641 C 486 486
248 Turkey 27642 A 486 486
249 Turkey 27643 C 486 486
250 Turkey 27644 C 486 486
251 Turkey 27645 T 486 486
252 Turkey 27646 A 486 486
253 Turkey 27647 A 486 486
254 Turkey 27648 A 486 486
255 Turkey 27649 C 486 486
256 Turkey 27650 T 486 486
257 Turkey 27651 G 486 486
258 Turkey 27652 T 486 486
259 Turkey 27653 T 486 486
260 Turkey 27654 C 486 486
261 Turkey 27655 A 486 486
262 Turkey 27656 T 486 486
263 Turkey 27657 C 486 486
264 Turkey 27658 A 486 486
265 Turkey 27659 G T 486 484 Arg89Ile
266 Turkey 27660 A 486 486
267 Turkey 27661 C 486 486
268 Turkey 27662 A G 486 485 Gln90Arg
269 Turkey 27663 A 486 486
270 Turkey 27664 G 486 486
271 Turkey 27665 A 486 486
272 Turkey 27666 G T 486 485 Glu91Asp
273 Turkey 27667 G 486 486
274 Turkey 27668 A 486 486
275 Turkey 27669 A 486 486
276 Turkey 27670 G 486 486
277 Turkey 27671 T 486 486
278 Turkey 27672 T 486 486
279 Turkey 27673 C 486 486
280 Turkey 27674 A 486 486
281 Turkey 27675 A 486 486
282 Turkey 27676 G 486 486
283 Turkey 27677 A 486 486
284 Turkey 27678 A G 486 485 Glu95Glu
285 Turkey 27679 C 486 486
286 Turkey 27680 T 486 486
287 Turkey 27681 T 486 486
288 Turkey 27682 T 486 486
289 Turkey 27683 A 486 486
290 Turkey 27684 C G 486 485 Tyr97*
291 Turkey 27685 T 486 486
292 Turkey 27686 C 486 486
293 Turkey 27687 T 486 486
294 Turkey 27688 C 486 486
295 Turkey 27689 C 486 486
296 Turkey 27690 A 486 486
297 Turkey 27691 A 486 486
298 Turkey 27692 T 486 486
299 Turkey 27693 T 486 486
300 Turkey 27694 T 486 486
301 Turkey 27695 T 486 486
302 Turkey 27696 T 486 486
303 Turkey 27697 C 486 486
304 Turkey 27698 T 486 486
305 Turkey 27699 T 486 486
306 Turkey 27700 A 486 486
307 Turkey 27701 T 486 486
308 Turkey 27702 T 486 486
309 Turkey 27703 G T 486 463 Val104Phe
310 Turkey 27704 T 486 486
311 Turkey 27705 T 486 486
312 Turkey 27706 G 486 486
313 Turkey 27707 C T 486 485 Ala105Val
314 Turkey 27708 G A 486 485 Ala105Ala
315 Turkey 27709 G 486 486
316 Turkey 27710 C 486 486
317 Turkey 27711 A 486 486
318 Turkey 27712 A 486 486
319 Turkey 27713 T 486 486
320 Turkey 27714 A 486 486
321 Turkey 27715 G 486 486
322 Turkey 27716 T 486 486
323 Turkey 27717 G 486 486
324 Turkey 27718 T 486 486
325 Turkey 27719 T 486 486
326 Turkey 27720 T 486 486
327 Turkey 27721 A 486 486
328 Turkey 27722 T 486 486
329 Turkey 27723 A 486 486
330 Turkey 27724 A 486 486
331 Turkey 27725 C 486 486
332 Turkey 27726 A 486 486
333 Turkey 27727 C 486 486
334 Turkey 27728 T 486 486
335 Turkey 27729 T 486 486
336 Turkey 27730 T 486 486
337 Turkey 27731 G 486 486
338 Turkey 27732 C 486 486
339 Turkey 27733 T 486 486
340 Turkey 27734 T 486 486
341 Turkey 27735 C 486 486
342 Turkey 27736 A 486 486
343 Turkey 27737 C 486 486
344 Turkey 27738 A 486 486
345 Turkey 27739 C T 486 485 Leu116Phe
346 Turkey 27740 T 486 486
347 Turkey 27741 C 486 486
348 Turkey 27742 A 486 486
349 Turkey 27743 A 486 486
350 Turkey 27744 A 486 486
351 Turkey 27745 A 486 486
352 Turkey 27746 G 486 486
353 Turkey 27747 A 486 486
354 Turkey 27748 A 486 486
355 Turkey 27749 A 486 486
356 Turkey 27750 G 486 486
357 Turkey 27751 A 486 486
358 Turkey 27752 C 486 486
359 Turkey 27753 A 486 486
360 Turkey 27754 G C 486 485 Glu121Gln
361 Turkey 27755 A 486 486
362 Turkey 27756 A 486 486
363 Turkey 27757 T 486 486
364 Turkey 27758 G 485 485
365 Turkey 27759 A 485 485