National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P Q R S T V Y
*     3                                      
-     370                                      
?                                            
A     27 1                             2 1    
C     18   1     1                            
D     6                                      
E 1   24     1                                
F     30         1         1           1      
G     12 1         1                   1   1  
H     9             1               1        
I     25                   1             1    
K     21                                      
L     45                   2                  
M     6                                      
N     6                       1              
P     18                   2           1      
Q 1   15                           1          
R     15                                      
S     21                                      
T     30 1             2                      
V     24         1                            
Y     15                                     1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Mexico 27394 A 594 594
1 Mexico 27395 T 594 594
2 Mexico 27396 G 594 594
3 Mexico 27397 A 594 594
4 Mexico 27398 A 594 594
5 Mexico 27399 A 594 594
6 Mexico 27400 A 594 594
7 Mexico 27401 T 594 594
8 Mexico 27402 T 594 594
9 Mexico 27403 A 595 595
10 Mexico 27404 T C 595 594 Ile4Thr
11 Mexico 27405 T 595 595
12 Mexico 27406 C 595 595
13 Mexico 27407 T 595 595
14 Mexico 27408 T 595 595
15 Mexico 27409 T 595 595
16 Mexico 27410 T 595 595
17 Mexico 27411 C 595 595
18 Mexico 27412 T 595 595
19 Mexico 27413 T 595 595
20 Mexico 27414 G 595 595
21 Mexico 27415 G A 595 594 Ala8Thr
22 Mexico 27416 C 595 595
23 Mexico 27417 A 595 595
24 Mexico 27418 C T 595 594 Leu9Leu
25 Mexico 27419 T 595 595
26 Mexico 27420 G 595 595
27 Mexico 27421 A 595 595
28 Mexico 27422 T 595 595
29 Mexico 27423 A 595 595
30 Mexico 27424 A 595 595
31 Mexico 27425 C 595 595
32 Mexico 27426 A 595 595
33 Mexico 27427 C 595 595
34 Mexico 27428 T 595 595
35 Mexico 27429 C 595 595
36 Mexico 27430 G 595 595
37 Mexico 27431 C 595 595
38 Mexico 27432 T 595 595
39 Mexico 27433 A G 595 594 Thr14Ala
40 Mexico 27434 C T 595 594 Thr14Ile
41 Mexico 27435 T 595 595
42 Mexico 27436 T 595 595
43 Mexico 27437 G 595 595
44 Mexico 27438 T 595 595
45 Mexico 27439 G 595 595
46 Mexico 27440 A 595 595
47 Mexico 27441 G T 595 594 Glu16Asp
48 Mexico 27442 C 595 595
49 Mexico 27443 T 595 595
50 Mexico 27444 T 595 595
51 Mexico 27445 T 595 595
52 Mexico 27446 A 595 595
53 Mexico 27447 T 595 595
54 Mexico 27448 C 595 595
55 Mexico 27449 A 595 595
56 Mexico 27450 C 595 595
57 Mexico 27451 T 595 595
58 Mexico 27452 A 595 595
59 Mexico 27453 C 595 595
60 Mexico 27454 C 595 595
61 Mexico 27455 A 595 595
62 Mexico 27456 A G 595 594 Gln21Gln
63 Mexico 27457 G 595 595
64 Mexico 27458 A 595 595
65 Mexico 27459 G 595 594
66 Mexico 27460 T 595 594
67 Mexico 27461 G 595 594
68 Mexico 27462 T 595 594
69 Mexico 27463 G 595 594
70 Mexico 27464 T 595 594
71 Mexico 27465 T 595 594
72 Mexico 27466 A 595 594
73 Mexico 27467 G 595 594
74 Mexico 27468 A 595 594
75 Mexico 27469 G 595 594
76 Mexico 27470 G 595 594
77 Mexico 27471 T 595 594
78 Mexico 27472 A 596 595
79 Mexico 27473 C 596 595
80 Mexico 27474 A 596 595
81 Mexico 27475 A 596 595
82 Mexico 27476 C 596 595
83 Mexico 27477 A 596 595
84 Mexico 27478 G 596 595
85 Mexico 27479 T 596 594
86 Mexico 27480 A 596 595
87 Mexico 27481 C 596 595
88 Mexico 27482 T 595 594
89 Mexico 27483 T 595 594
90 Mexico 27484 T 595 594
91 Mexico 27485 T 595 593
92 Mexico 27486 A 595 594
93 Mexico 27487 A 595 594
94 Mexico 27488 A 595 594
95 Mexico 27489 A 595 594
96 Mexico 27490 G 595 594
97 Mexico 27491 A 595 594
98 Mexico 27492 A 595 594
99 Mexico 27493 C 595 594
100 Mexico 27494 C T 595 593 Pro34Leu
101 Mexico 27495 T 595 594
102 Mexico 27496 T 595 594
103 Mexico 27497 G T 595 593 Cys35Phe
104 Mexico 27498 C 595 594
105 Mexico 27499 T 595 594
106 Mexico 27500 C 595 594
107 Mexico 27501 T 595 594
108 Mexico 27502 T 595 594
109 Mexico 27503 C 595 594
110 Mexico 27504 T 595 594
111 Mexico 27505 G 595 594
112 Mexico 27506 G T,C 595 591 Gly38Val-p.Gly38Ala
113 Mexico 27507 A 595 594
114 Mexico 27508 A 595 594
115 Mexico 27509 C 595 594
116 Mexico 27510 A 595 594
117 Mexico 27511 T 595 594
118 Mexico 27512 A 585 584
119 Mexico 27513 C T 585 582 Tyr40Tyr
120 Mexico 27514 G 585 585
121 Mexico 27515 A 585 585
122 Mexico 27516 G 585 585
123 Mexico 27517 G A 585 584 Gly42Ser
124 Mexico 27518 G 585 585
125 Mexico 27519 C 585 585
126 Mexico 27520 A 585 585
127 Mexico 27521 A 585 585
128 Mexico 27522 T 585 585
129 Mexico 27523 T 585 585
130 Mexico 27524 C 585 585
131 Mexico 27525 A 583 583
132 Mexico 27526 C 583 583
133 Mexico 27527 C 580 579
134 Mexico 27528 A 574 571
135 Mexico 27529 T 574 571
136 Mexico 27530 T 574 571
137 Mexico 27531 T 574 571
138 Mexico 27532 C 574 571
139 Mexico 27533 A G 574 570 His47Arg
140 Mexico 27534 T C 574 571 His47His
141 Mexico 27535 C 574 572
142 Mexico 27536 C 574 572
143 Mexico 27537 T 574 572
144 Mexico 27538 C 574 572
145 Mexico 27539 T 574 572
146 Mexico 27540 A 574 572
147 Mexico 27541 G 574 572
148 Mexico 27542 C 574 572
149 Mexico 27543 T 574 572
150 Mexico 27544 G 574 572
151 Mexico 27545 A 574 572
152 Mexico 27546 T 574 572
153 Mexico 27547 A 574 572
154 Mexico 27548 A 574 572
155 Mexico 27549 C T 574 571 Asn52Asn
156 Mexico 27550 A 574 572
157 Mexico 27551 A 574 573
158 Mexico 27552 A 574 573
159 Mexico 27553 T 574 573
160 Mexico 27554 T 574 571
161 Mexico 27555 T 574 571
162 Mexico 27556 G 574 571
163 Mexico 27557 C 574 571
164 Mexico 27558 A 574 571
165 Mexico 27559 C 574 570
166 Mexico 27560 T 574 569
167 Mexico 27561 G T 574 570 Leu56Leu
168 Mexico 27562 A 574 571
169 Mexico 27563 C 574 571
170 Mexico 27564 T 574 571
171 Mexico 27565 T 574 571
172 Mexico 27566 G 575 572
173 Mexico 27567 C 575 573
174 Mexico 27568 T 575 573
175 Mexico 27569 T 575 573
176 Mexico 27570 T 575 574
177 Mexico 27571 A 575 574
178 Mexico 27572 G 575 574
179 Mexico 27573 C 575 574
180 Mexico 27574 A 574 573
181 Mexico 27575 C 574 573
182 Mexico 27576 T 574 572
183 Mexico 27577 C 574 572
184 Mexico 27578 A 574 572
185 Mexico 27579 A 574 571
186 Mexico 27580 T 574 571
187 Mexico 27581 T 574 571
188 Mexico 27582 T 574 571
189 Mexico 27583 G T 574 573 Ala64Ser
190 Mexico 27584 C 574 574
191 Mexico 27585 T 574 574
192 Mexico 27586 T 574 574
193 Mexico 27587 T 574 574
194 Mexico 27588 T 574 574
195 Mexico 27589 G 574 574
196 Mexico 27590 C 574 574
197 Mexico 27591 T 574 574
198 Mexico 27592 T 574 574
199 Mexico 27593 G 574 574
200 Mexico 27594 T 574 574
201 Mexico 27595 C 573 573
202 Mexico 27596 C T 573 572 Pro68Leu
203 Mexico 27597 T 573 573
204 Mexico 27598 G 573 573
205 Mexico 27599 A 573 572
206 Mexico 27600 C 573 573
207 Mexico 27601 G 572 571
208 Mexico 27602 G 572 571
209 Mexico 27603 C T 572 570 Gly70Gly
210 Mexico 27604 G 572 571
211 Mexico 27605 T 572 571
212 Mexico 27606 A 572 571
213 Mexico 27607 A 572 571
214 Mexico 27608 A 572 571
215 Mexico 27609 A 572 571
216 Mexico 27610 C 571 570
217 Mexico 27611 A 571 570
218 Mexico 27612 C 571 570
219 Mexico 27613 G 571 570
220 Mexico 27614 T 570 569
221 Mexico 27615 C 570 569
222 Mexico 27616 T 570 569
223 Mexico 27617 A 570 569
224 Mexico 27618 T 570 569
225 Mexico 27619 C 570 569
226 Mexico 27620 A 570 569
227 Mexico 27621 G 570 569
228 Mexico 27622 T 570 569
229 Mexico 27623 T 570 569
230 Mexico 27624 A 570 569
231 Mexico 27625 C 570 569
232 Mexico 27626 G 570 569
233 Mexico 27627 T 570 569
234 Mexico 27628 G 570 569
235 Mexico 27629 C 570 569
236 Mexico 27630 C T 570 568 Ala79Ala
237 Mexico 27631 A 570 569
238 Mexico 27632 G 570 569
239 Mexico 27633 A 570 569
240 Mexico 27634 T 571 570
241 Mexico 27635 C 571 570
242 Mexico 27636 A 571 570
243 Mexico 27637 G 571 570
244 Mexico 27638 T 571 570
245 Mexico 27639 T 571 570
246 Mexico 27640 T 571 570
247 Mexico 27641 C 571 571
248 Mexico 27642 A 571 571
249 Mexico 27643 C T 571 570 Pro84Ser
250 Mexico 27644 C 571 571
251 Mexico 27645 T 571 571
252 Mexico 27646 A 571 571
253 Mexico 27647 A 571 571
254 Mexico 27648 A 571 571
255 Mexico 27649 C 571 570
256 Mexico 27650 T 569 568
257 Mexico 27651 G 569 567
258 Mexico 27652 T C 569 566 Phe87Leu
259 Mexico 27653 T C 569 566 Phe87Ser
260 Mexico 27654 C T 569 565 Phe87Phe
261 Mexico 27655 A C 568 565 Ile88Leu
262 Mexico 27656 T 568 566
263 Mexico 27657 C 568 566
264 Mexico 27658 A 568 566
265 Mexico 27659 G 568 567
266 Mexico 27660 A 568 567
267 Mexico 27661 C 568 567
268 Mexico 27662 A 568 567
269 Mexico 27663 A 568 568
270 Mexico 27664 G 568 568
271 Mexico 27665 A 568 568
272 Mexico 27666 G 568 568
273 Mexico 27667 G 568 568
274 Mexico 27668 A 568 568
275 Mexico 27669 A 568 568
276 Mexico 27670 G 568 567
277 Mexico 27671 T 568 567
278 Mexico 27672 T 567 566
279 Mexico 27673 C T 567 565 Gln94*
280 Mexico 27674 A 567 567
281 Mexico 27675 A 567 567
282 Mexico 27676 G T 567 565 Glu95*
283 Mexico 27677 A 567 567
284 Mexico 27678 A 567 567
285 Mexico 27679 C 566 566
286 Mexico 27680 T 566 566
287 Mexico 27681 T 566 566
288 Mexico 27682 T 565 565
289 Mexico 27683 A 565 565
290 Mexico 27684 C 565 565
291 Mexico 27685 T 565 565
292 Mexico 27686 C 565 565
293 Mexico 27687 T 565 565
294 Mexico 27688 C 565 565
295 Mexico 27689 C 565 565
296 Mexico 27690 A 565 565
297 Mexico 27691 A 565 565
298 Mexico 27692 T 565 565
299 Mexico 27693 T 565 565
300 Mexico 27694 T 565 565
301 Mexico 27695 T 565 565
302 Mexico 27696 T 565 565
303 Mexico 27697 C 565 565
304 Mexico 27698 T 565 565
305 Mexico 27699 T 565 565
306 Mexico 27700 A 565 565
307 Mexico 27701 T 563 563
308 Mexico 27702 T 563 563
309 Mexico 27703 G T 563 561 Val104Phe
310 Mexico 27704 T 563 563
311 Mexico 27705 T 563 563
312 Mexico 27706 G 563 563
313 Mexico 27707 C 563 563
314 Mexico 27708 G 563 563
315 Mexico 27709 G T 563 561 Ala106Ser
316 Mexico 27710 C 563 563
317 Mexico 27711 A 563 563
318 Mexico 27712 A 563 563
319 Mexico 27713 T 563 563
320 Mexico 27714 A 563 563
321 Mexico 27715 G 563 563
322 Mexico 27716 T 562 562
323 Mexico 27717 G 561 561
324 Mexico 27718 T 561 560
325 Mexico 27719 T 561 561
326 Mexico 27720 T 561 561
327 Mexico 27721 A 561 561
328 Mexico 27722 T 561 561
329 Mexico 27723 A 561 561
330 Mexico 27724 A 561 561
331 Mexico 27725 C 561 561
332 Mexico 27726 A 561 561
333 Mexico 27727 C 561 561
334 Mexico 27728 T 560 560
335 Mexico 27729 T 560 560
336 Mexico 27730 T 560 560
337 Mexico 27731 G 560 560
338 Mexico 27732 C T 560 558 Cys113Cys
339 Mexico 27733 T 560 559
340 Mexico 27734 T 560 559
341 Mexico 27735 C 560 559
342 Mexico 27736 A 560 559
343 Mexico 27737 C 560 559
344 Mexico 27738 A 560 559
345 Mexico 27739 C 560 560
346 Mexico 27740 T 559 559
347 Mexico 27741 C 559 558
348 Mexico 27742 A 559 559
349 Mexico 27743 A 559 559
350 Mexico 27744 A 559 559
351 Mexico 27745 A 559 559
352 Mexico 27746 G 559 559
353 Mexico 27747 A 559 559
354 Mexico 27748 A 559 559
355 Mexico 27749 A 559 559
356 Mexico 27750 G 559 559
357 Mexico 27751 A 559 559
358 Mexico 27752 C T 559 558 Thr120Ile
359 Mexico 27753 A 559 559
360 Mexico 27754 G 558 558
361 Mexico 27755 A 558 558
362 Mexico 27756 A 558 558
363 Mexico 27757 T 558 558
364 Mexico 27758 G 558 558
365 Mexico 27759 A 557 557