National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D F G I L M N P Q R S T V Y
*     2                                
-     117                                
?                                      
A     6                             2  
C     3   1                            
D     3     1                         1
F     12             1           1      
G     3     1                          
I     9                             1  
L     12       1     1     1            
M     6                                
N     16     1           1       1      
P     3             1           1      
Q 1   3             1       1          
R     6   1       1 1         1   1    
S     6       1                        
T     6                           1    
V     12             1                  
Y     9                                

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Switzerland 29558 A 8055 8055
1 Switzerland 29559 T 8055 8053
2 Switzerland 29560 G 8055 8054
3 Switzerland 29561 G 8055 8055
4 Switzerland 29562 G A 8055 8051 Gly2Asp
5 Switzerland 29563 C 8055 8054
6 Switzerland 29564 T 8055 8054
7 Switzerland 29565 A 8055 8054
8 Switzerland 29566 T 8055 8055
9 Switzerland 29567 A G 8055 8053 Ile4Val
10 Switzerland 29568 T 8055 8055
11 Switzerland 29569 A 8055 8054
12 Switzerland 29570 A 8055 8054
13 Switzerland 29571 A G 8055 8054 Asn5Ser
14 Switzerland 29572 C 8055 8053
15 Switzerland 29573 G 8055 8054
16 Switzerland 29574 T 8055 8055
17 Switzerland 29575 T 8055 8055
18 Switzerland 29576 T 8055 8055
19 Switzerland 29577 T 8055 8055
20 Switzerland 29578 C A 8055 8054 Phe7Leu
21 Switzerland 29579 G 8055 8054
22 Switzerland 29580 C T 8055 8048 Ala8Val
23 Switzerland 29581 T 8055 8052
24 Switzerland 29582 T 8055 8055
25 Switzerland 29583 T C 8055 8050 Phe9Ser
26 Switzerland 29584 T 8055 8053
27 Switzerland 29585 C T 8055 8042 Pro10Ser
28 Switzerland 29586 C T 8055 8052 Pro10Leu
29 Switzerland 29587 G 8055 8053
30 Switzerland 29588 T 8055 8055
31 Switzerland 29589 T 8055 8055
32 Switzerland 29590 T 8055 8055
33 Switzerland 29591 A 8055 8055
34 Switzerland 29592 C 8055 8054
35 Switzerland 29593 G A 8055 8027 Thr12Thr
36 Switzerland 29594 A 8055 8054
37 Switzerland 29595 T 8055 8055
38 Switzerland 29596 A 8055 8054
39 Switzerland 29597 T 8055 8055
40 Switzerland 29598 A 8055 8055
41 Switzerland 29599 T 8055 8053
42 Switzerland 29600 A 8055 8052
43 Switzerland 29601 G 8055 8054
44 Switzerland 29602 T 8055 8055
45 Switzerland 29603 C 8055 8054
46 Switzerland 29604 T C 8055 8052 Leu16Pro
47 Switzerland 29605 A 8055 8054
48 Switzerland 29606 C 8055 8055
49 Switzerland 29607 T 8055 8055
50 Switzerland 29608 C 8055 8054
51 Switzerland 29609 T 8055 8055
52 Switzerland 29610 T 8055 8053
53 Switzerland 29611 G 8055 8054
54 Switzerland 29612 T 8055 8055
55 Switzerland 29613 G 8055 8052
56 Switzerland 29614 C T 8055 8012 Cys19Cys
57 Switzerland 29615 A C 8055 8053 Arg20Arg
58 Switzerland 29616 G C,T 8055 8052 Arg20Thr-p.Arg20Ile
59 Switzerland 29617 A 8057 8055
60 Switzerland 29618 A 8058 8058
61 Switzerland 29619 T 8058 8057
62 Switzerland 29620 G 8058 8053
63 Switzerland 29621 A G 8058 8056 Asn22Asp
64 Switzerland 29622 A 8058 8058
65 Switzerland 29623 T 8058 8056
66 Switzerland 29624 T 8058 8058
67 Switzerland 29625 C T 8058 8052 Ser23Phe
68 Switzerland 29626 T 8058 8057
69 Switzerland 29627 C T 8058 8046 Arg24Cys
70 Switzerland 29628 G T 8058 8053 Arg24Leu
71 Switzerland 29629 T 8058 8055
72 Switzerland 29630 A 8058 8057
73 Switzerland 29631 A 8058 8057
74 Switzerland 29632 C T 8058 8049 Asn25Asn
75 Switzerland 29633 T 8058 8056
76 Switzerland 29634 A 8058 8056
77 Switzerland 29635 C 8058 8057
78 Switzerland 29636 A 8058 8058
79 Switzerland 29637 T 8058 8055
80 Switzerland 29638 A 8057 8053
81 Switzerland 29639 G 8057 8055
82 Switzerland 29640 C T 8057 8046 Ala28Val
83 Switzerland 29641 A 8057 8057
84 Switzerland 29642 C T 8057 8040 Gln29*
85 Switzerland 29643 A T 8055 8052 Gln29Leu
86 Switzerland 29644 A G 8055 8054 Gln29Gln
87 Switzerland 29645 G T 8055 6127 Val30Leu
88 Switzerland 29646 T 8054 8052
89 Switzerland 29647 A 8053 8049
90 Switzerland 29648 G T 8053 8046 Asp31Tyr
91 Switzerland 29649 A 8053 8053
92 Switzerland 29650 T C 8053 8051 Asp31Asp
93 Switzerland 29651 G 8052 8052
94 Switzerland 29652 T 8052 8050
95 Switzerland 29653 A 8052 8051
96 Switzerland 29654 G 8052 8052
97 Switzerland 29655 T 8050 8050
98 Switzerland 29656 T 8050 8050
99 Switzerland 29657 A 8049 8048
100 Switzerland 29658 A 8049 8049
101 Switzerland 29659 C 8049 8049
102 Switzerland 29660 T 8049 8049
103 Switzerland 29661 T 8049 8049
104 Switzerland 29662 T 8045 8045
105 Switzerland 29663 A 8043 8042
106 Switzerland 29664 A 8043 8042
107 Switzerland 29665 T 8043 8041
108 Switzerland 29666 C T 8040 8035 Leu37Phe
109 Switzerland 29667 T 8037 8037
110 Switzerland 29668 C T 8034 8031 Leu37Leu
111 Switzerland 29669 A 8034 8031
112 Switzerland 29670 C 8034 8033
113 Switzerland 29671 A 8034 8034
114 Switzerland 29672 T 8033 8033
115 Switzerland 29673 A 8032 8032
116 Switzerland 29674 G 8032 8032