National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D F G I K L M N P Q R S T V Y
*     2                                  
-     117                                  
?                                        
A     6 1                         1   2  
C     3   1                              
D     3                                 1
F     12               1           1      
G     3                                  
I     9                             1    
K                                        
L     12       1   1   1                  
M     6             1                    
N     16     1             2       2      
P     3               1     1     1      
Q     3                                  
R     6   1           1                  
S     6       1 1                        
T     6           1                 1    
V     12 1             1               1  
Y     9                                  

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Spain 29558 A 7380 7380
1 Spain 29559 T 7381 7381
2 Spain 29560 G 7381 7381
3 Spain 29561 G 7381 7381
4 Spain 29562 G 7381 7380
5 Spain 29563 C 7382 7382
6 Spain 29564 T 7382 7382
7 Spain 29565 A 7382 7382
8 Spain 29566 T 7382 7382
9 Spain 29567 A 7382 7382
10 Spain 29568 T 7382 7382
11 Spain 29569 A 7382 7382
12 Spain 29570 A G 7382 7376 Asn5Asp
13 Spain 29571 A 7382 7381
14 Spain 29572 C 7382 7382
15 Spain 29573 G 7382 7382
16 Spain 29574 T 7382 7382
17 Spain 29575 T 7382 7381
18 Spain 29576 T 7382 7381
19 Spain 29577 T 7382 7381
20 Spain 29578 C 7383 7382
21 Spain 29579 G 7386 7385
22 Spain 29580 C T 7386 7384 Ala8Val
23 Spain 29581 T C 7386 7383 Ala8Ala
24 Spain 29582 T C 7386 7384 Phe9Leu
25 Spain 29583 T 7386 7385
26 Spain 29584 T 7386 7385
27 Spain 29585 C T 7386 7255 Pro10Ser
28 Spain 29586 C T 7387 7385 Pro10Leu
29 Spain 29587 G T 7387 7385 Pro10Pro
30 Spain 29588 T 7387 7384
31 Spain 29589 T C 7387 7365 Phe11Ser
32 Spain 29590 T 7387 7386
33 Spain 29591 A 7387 7386
34 Spain 29592 C 7387 7386
35 Spain 29593 G T 7387 7384 Thr12Thr
36 Spain 29594 A 7387 7386
37 Spain 29595 T 7387 7386
38 Spain 29596 A 7387 7386
39 Spain 29597 T 7387 7386
40 Spain 29598 A 7387 7386
41 Spain 29599 T 7387 7386
42 Spain 29600 A G 7387 7385 Ser15Gly
43 Spain 29601 G 7387 7386
44 Spain 29602 T 7387 7386
45 Spain 29603 C A 7387 7384 Leu16Ile
46 Spain 29604 T 7387 7386
47 Spain 29605 A 7387 7385
48 Spain 29606 C 7387 7386
49 Spain 29607 T 7387 7386
50 Spain 29608 C 7387 7386
51 Spain 29609 T 7387 7386
52 Spain 29610 T 7385 7384
53 Spain 29611 G 7385 7384
54 Spain 29612 T 7385 7384
55 Spain 29613 G 7385 7384
56 Spain 29614 C T 7385 7343 Cys19Cys
57 Spain 29615 A 7385 7384
58 Spain 29616 G 7385 7384
59 Spain 29617 A 7385 7384
60 Spain 29618 A 7386 7385
61 Spain 29619 T A 7386 7367 Met21Lys
62 Spain 29620 G 7386 7385
63 Spain 29621 A 7386 7385
64 Spain 29622 A G 7386 7384 Asn22Ser
65 Spain 29623 T C 7385 7382 Asn22Asn
66 Spain 29624 T 7385 7384
67 Spain 29625 C T 7385 7379 Ser23Phe
68 Spain 29626 T 7385 7384
69 Spain 29627 C T 7385 7379 Arg24Cys
70 Spain 29628 G T 7385 7383 Arg24Leu
71 Spain 29629 T 7385 7385
72 Spain 29630 A 7385 7385
73 Spain 29631 A G 7385 7384 Asn25Ser
74 Spain 29632 C 7385 7385
75 Spain 29633 T 7385 7385
76 Spain 29634 A 7385 7385
77 Spain 29635 C 7385 7383
78 Spain 29636 A 7385 7385
79 Spain 29637 T C 7385 7382 Ile27Thr
80 Spain 29638 A 7385 7385
81 Spain 29639 G T 7385 7379 Ala28Ser
82 Spain 29640 C T 7385 7380 Ala28Val
83 Spain 29641 A 7385 7384
84 Spain 29642 C 7385 7382
85 Spain 29643 A 7384 7383
86 Spain 29644 A 7384 7384
87 Spain 29645 G T 7384 5260 Val30Leu
88 Spain 29646 T C 7384 7383 Val30Ala
89 Spain 29647 A G 7384 7383 Val30Val
90 Spain 29648 G T 7384 7382 Asp31Tyr
91 Spain 29649 A 7384 7384
92 Spain 29650 T 7384 7383
93 Spain 29651 G 7384 7384
94 Spain 29652 T 7384 7384
95 Spain 29653 A 7383 7383
96 Spain 29654 G 7383 7383
97 Spain 29655 T 7381 7381
98 Spain 29656 T 7381 7381
99 Spain 29657 A 7380 7380
100 Spain 29658 A 7380 7380
101 Spain 29659 C T 7380 7378 Asn34Asn
102 Spain 29660 T 7380 7379
103 Spain 29661 T 7380 7380
104 Spain 29662 T 7380 7380
105 Spain 29663 A 7380 7380
106 Spain 29664 A 7380 7380
107 Spain 29665 T 7380 7380
108 Spain 29666 C T 7362 7360 Leu37Phe
109 Spain 29667 T 7361 7361
110 Spain 29668 C T 7360 7359 Leu37Leu
111 Spain 29669 A 7360 7360
112 Spain 29670 C T 7360 7349 Thr38Ile
113 Spain 29671 A 7359 7359
114 Spain 29672 T 7359 7359
115 Spain 29673 A 7359 7359
116 Spain 29674 G 7358 7358