National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D F G H I L M N P Q R S T V W Y
*     2                                    
-     117                                    
?                                          
A     6 1                         1   1    
C     3   1                             1  
D     3                                    
F     12               2                    
G     3                                    
H                                          
I     9               1             1      
L     12       1       2                    
M     6             1                      
N     16                   1                
P     3               1     1     1        
Q 1   3                                    
R 1   6   1           1                    
S     6   1   1                   1        
T     6             1               1      
V     12               1               2    
W                                          
Y     9   1       1                       1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Netherlands 29558 A 5665 5665
1 Netherlands 29559 T 5666 5666
2 Netherlands 29560 G 5666 5666
3 Netherlands 29561 G 5666 5666
4 Netherlands 29562 G 5666 5666
5 Netherlands 29563 C 5666 5666
6 Netherlands 29564 T 5666 5666
7 Netherlands 29565 A 5666 5666
8 Netherlands 29566 T 5666 5666
9 Netherlands 29567 A C 5666 5665 Ile4Leu
10 Netherlands 29568 T 5666 5666
11 Netherlands 29569 A 5666 5666
12 Netherlands 29570 A 5666 5666
13 Netherlands 29571 A 5666 5666
14 Netherlands 29572 C 5666 5666
15 Netherlands 29573 G 5666 5666
16 Netherlands 29574 T 5666 5666
17 Netherlands 29575 T 5666 5666
18 Netherlands 29576 T 5666 5666
19 Netherlands 29577 T 5666 5666
20 Netherlands 29578 C 5666 5666
21 Netherlands 29579 G 5666 5666
22 Netherlands 29580 C 5666 5666
23 Netherlands 29581 T C 5666 5665 Ala8Ala
24 Netherlands 29582 T C 5666 5664 Phe9Leu
25 Netherlands 29583 T 5666 5666
26 Netherlands 29584 T 5666 5666
27 Netherlands 29585 C T 5666 5664 Pro10Ser
28 Netherlands 29586 C T 5666 5665 Pro10Leu
29 Netherlands 29587 G T 5666 5665 Pro10Pro
30 Netherlands 29588 T 5666 5666
31 Netherlands 29589 T 5666 5666
32 Netherlands 29590 T 5666 5666
33 Netherlands 29591 A 5666 5666
34 Netherlands 29592 C 5666 5666
35 Netherlands 29593 G T 5666 5653 Thr12Thr
36 Netherlands 29594 A 5666 5666
37 Netherlands 29595 T 5666 5666
38 Netherlands 29596 A 5666 5666
39 Netherlands 29597 T 5666 5666
40 Netherlands 29598 A G 5666 5665 Tyr14Cys
41 Netherlands 29599 T 5666 5666
42 Netherlands 29600 A 5666 5666
43 Netherlands 29601 G 5666 5666
44 Netherlands 29602 T 5666 5666
45 Netherlands 29603 C 5666 5666
46 Netherlands 29604 T 5666 5666
47 Netherlands 29605 A 5666 5666
48 Netherlands 29606 C 5666 5666
49 Netherlands 29607 T 5666 5666
50 Netherlands 29608 C 5666 5666
51 Netherlands 29609 T C 5666 5665 Leu18Leu
52 Netherlands 29610 T 5666 5666
53 Netherlands 29611 G 5666 5666
54 Netherlands 29612 T 5666 5666
55 Netherlands 29613 G 5666 5666
56 Netherlands 29614 C T,G 5666 5611 Cys19Trp-p.Cys19Cys
57 Netherlands 29615 A T 5666 5665 Arg20*
58 Netherlands 29616 G 5666 5666
59 Netherlands 29617 A 5666 5666
60 Netherlands 29618 A 5667 5667
61 Netherlands 29619 T 5667 5667
62 Netherlands 29620 G C 5667 5666 Met21Ile
63 Netherlands 29621 A 5667 5667
64 Netherlands 29622 A 5667 5667
65 Netherlands 29623 T 5667 5667
66 Netherlands 29624 T 5667 5667
67 Netherlands 29625 C T,G 5667 5653 Ser23Phe-p.Ser23Cys
68 Netherlands 29626 T C 5667 5666 Ser23Ser
69 Netherlands 29627 C T 5667 5663 Arg24Cys
70 Netherlands 29628 G T 5667 5637 Arg24Leu
71 Netherlands 29629 T 5667 5667
72 Netherlands 29630 A 5667 5667
73 Netherlands 29631 A 5667 5667
74 Netherlands 29632 C 5667 5667
75 Netherlands 29633 T C 5667 5663 Tyr26His
76 Netherlands 29634 A 5667 5667
77 Netherlands 29635 C T 5667 5666 Tyr26Tyr
78 Netherlands 29636 A 5667 5667
79 Netherlands 29637 T C 5667 5666 Ile27Thr
80 Netherlands 29638 A 5667 5667
81 Netherlands 29639 G T 5667 5666 Ala28Ser
82 Netherlands 29640 C T 5667 5666 Ala28Val
83 Netherlands 29641 A 5667 5667
84 Netherlands 29642 C T 5667 5663 Gln29*
85 Netherlands 29643 A 5667 5667
86 Netherlands 29644 A 5667 5667
87 Netherlands 29645 G T 5667 4491 Val30Leu
88 Netherlands 29646 T 5667 5667
89 Netherlands 29647 A G 5667 5666 Val30Val
90 Netherlands 29648 G 5667 5667
91 Netherlands 29649 A 5667 5667
92 Netherlands 29650 T 5667 5667
93 Netherlands 29651 G 5667 5667
94 Netherlands 29652 T 5667 5667
95 Netherlands 29653 A G 5667 5666 Val32Val
96 Netherlands 29654 G 5667 5667
97 Netherlands 29655 T 5667 5667
98 Netherlands 29656 T 5667 5667
99 Netherlands 29657 A 5667 5667
100 Netherlands 29658 A 5667 5667
101 Netherlands 29659 C T 5667 5666 Asn34Asn
102 Netherlands 29660 T C 5667 5666 Phe35Leu
103 Netherlands 29661 T 5667 5667
104 Netherlands 29662 T 5667 5667
105 Netherlands 29663 A 5665 5665
106 Netherlands 29664 A 5665 5665
107 Netherlands 29665 T 5665 5665
108 Netherlands 29666 C T 5665 5664 Leu37Phe
109 Netherlands 29667 T 5665 5665
110 Netherlands 29668 C T 5664 5663 Leu37Leu
111 Netherlands 29669 A 5664 5664
112 Netherlands 29670 C T 5664 5661 Thr38Ile
113 Netherlands 29671 A 5664 5664
114 Netherlands 29672 T 5664 5664
115 Netherlands 29673 A 5664 5664
116 Netherlands 29674 G 5664 5664