National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D F G H I K L M N P Q R S T V Y
*     2                                    
-     117                                    
?                                          
A     6                                 1  
C     3       1                            
D     3         1                       1  
F     12                 1                  
G     3                                    
H                                          
I     9                               1 1  
K                                          
L     12       1                            
M     6                                    
N     16             1               1      
P     3                 1                  
Q     3               1                    
R     6                                    
S     6       1                     1      
T     6             1                 1    
V     12             2   1               2  
Y     9           1                       1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 China 29558 A 933 933
1 China 29559 T 933 933
2 China 29560 G 934 934
3 China 29561 G 934 934
4 China 29562 G 934 934
5 China 29563 C 934 934
6 China 29564 T 934 930
7 China 29565 A 934 934
8 China 29566 T 934 934
9 China 29567 A G 934 928 Ile4Val
10 China 29568 T 934 934
11 China 29569 A 934 934
12 China 29570 A 934 934
13 China 29571 A 935 935
14 China 29572 C 935 935
15 China 29573 G A 935 934 Val6Ile
16 China 29574 T 935 935
17 China 29575 T G 935 934 Val6Val
18 China 29576 T 935 934
19 China 29577 T 935 935
20 China 29578 C 935 935
21 China 29579 G 935 934
22 China 29580 C 935 934
23 China 29581 T 935 933
24 China 29582 T 935 934
25 China 29583 T 935 934
26 China 29584 T 935 934
27 China 29585 C 935 934
28 China 29586 C T 935 932 Pro10Leu
29 China 29587 G 935 934
30 China 29588 T 935 934
31 China 29589 T 935 934
32 China 29590 T 934 933
33 China 29591 A 934 933
34 China 29592 C 934 934
35 China 29593 G A 934 932 Thr12Thr
36 China 29594 A 934 934
37 China 29595 T 934 934
38 China 29596 A 934 934
39 China 29597 T C 934 928 Tyr14His
40 China 29598 A 934 934
41 China 29599 T 934 934
42 China 29600 A 934 934
43 China 29601 G 934 934
44 China 29602 T 934 934
45 China 29603 C 934 934
46 China 29604 T 934 934
47 China 29605 A 934 934
48 China 29606 C 934 934
49 China 29607 T 934 934
50 China 29608 C 934 934
51 China 29609 T 934 934
52 China 29610 T 933 933
53 China 29611 G 933 933
54 China 29612 T 933 933
55 China 29613 G T 933 932 Cys19Phe
56 China 29614 C 933 933
57 China 29615 A 933 933
58 China 29616 G 933 933
59 China 29617 A 933 933
60 China 29618 A 933 933
61 China 29619 T 933 933
62 China 29620 G 933 933
63 China 29621 A 933 933
64 China 29622 A 933 932
65 China 29623 T 933 933
66 China 29624 T 933 933
67 China 29625 C T 933 931 Ser23Phe
68 China 29626 T G 933 932 Ser23Ser
69 China 29627 C 933 933
70 China 29628 G 933 933
71 China 29629 T 933 933
72 China 29630 A 933 933
73 China 29631 A G 933 920 Asn25Ser
74 China 29632 C 933 933
75 China 29633 T 933 933
76 China 29634 A 933 933
77 China 29635 C T 933 927 Tyr26Tyr
78 China 29636 A 933 933
79 China 29637 T C 933 927 Ile27Thr
80 China 29638 A 933 933
81 China 29639 G 933 933
82 China 29640 C T 933 928 Ala28Val
83 China 29641 A 933 933
84 China 29642 C A 933 932 Gln29Lys
85 China 29643 A 933 933
86 China 29644 A 933 933
87 China 29645 G C 933 931 Val30Leu
88 China 29646 T 933 933
89 China 29647 A 933 933
90 China 29648 G 933 933
91 China 29649 A G,T 932 926 Asp31Gly-p.Asp31Val
92 China 29650 T 932 932
93 China 29651 G A 932 926 Val32Ile
94 China 29652 T 932 932
95 China 29653 A 932 932
96 China 29654 G 932 932
97 China 29655 T 932 932
98 China 29656 T C 932 931 Val33Val
99 China 29657 A 932 932
100 China 29658 A 932 932
101 China 29659 C 932 932
102 China 29660 T C 932 931 Phe35Leu
103 China 29661 T 931 931
104 China 29662 T 931 931
105 China 29663 A 931 931
106 China 29664 A T 931 930 Asn36Ile
107 China 29665 T 931 931
108 China 29666 C T 924 923 Leu37Phe
109 China 29667 T 924 924
110 China 29668 C 924 923
111 China 29669 A 924 923
112 China 29670 C T 923 922 Thr38Ile
113 China 29671 A 923 923
114 China 29672 T 923 923
115 China 29673 A 922 922
116 China 29674 G 922 922