National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.
Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D F G I L M N P Q R S T V Y
*     2                     1          
-     117                                
?                                      
A     6                   1     2 1 1  
C     3   1                            
D     3         1                     1
F     12             1                  
G     3         1                      
I     9                             2  
L     12       2     1                  
M     6                                
N     16                 1         1    
P     3             1     2     1      
Q 1   3                                
R     6   1                            
S     6       1                 1      
T     6           1               1    
V     12           1 1               1  
Y     9   2                           1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Australia 29558 A 17129 17129
1 Australia 29559 T 17130 17129
2 Australia 29560 G 17131 17123
3 Australia 29561 G 17132 17132
4 Australia 29562 G 17134 17133
5 Australia 29563 C T 17134 17131 Gly2Gly
6 Australia 29564 T 17134 17134
7 Australia 29565 A G 17134 17131 Tyr3Cys
8 Australia 29566 T 17134 17133
9 Australia 29567 A G 17134 17131 Ile4Val
10 Australia 29568 T 17134 17133
11 Australia 29569 A 17134 17134
12 Australia 29570 A 17134 17134
13 Australia 29571 A 17134 17133
14 Australia 29572 C 17134 17133
15 Australia 29573 G 17134 17134
16 Australia 29574 T 17134 17130
17 Australia 29575 T 17134 17132
18 Australia 29576 T 17134 17132
19 Australia 29577 T 17134 17132
20 Australia 29578 C 17134 17131
21 Australia 29579 G A,T 17135 17100 Ala8Thr-p.Ala8Ser
22 Australia 29580 C T 17135 17130 Ala8Val
23 Australia 29581 T 17135 17121
24 Australia 29582 T 17135 17134
25 Australia 29583 T 17135 17135
26 Australia 29584 T 17135 17133
27 Australia 29585 C T 17135 17106 Pro10Ser
28 Australia 29586 C T 17135 17133 Pro10Leu
29 Australia 29587 G T,A 17135 17133 Pro10Pro-p.Pro10Pro
30 Australia 29588 T C 17135 17133 Phe11Leu
31 Australia 29589 T 17133 17133
32 Australia 29590 T 17133 17133
33 Australia 29591 A 17132 17131
34 Australia 29592 C 17132 17129
35 Australia 29593 G T 17132 17130 Thr12Thr
36 Australia 29594 A G 17132 17131 Ile13Val
37 Australia 29595 T 17132 17132
38 Australia 29596 A 17128 17128
39 Australia 29597 T 17128 17128
40 Australia 29598 A G 17127 17125 Tyr14Cys
41 Australia 29599 T 17128 17127
42 Australia 29600 A 17128 17126
43 Australia 29601 G 17127 17125
44 Australia 29602 T 17127 17124
45 Australia 29603 C 17127 17125
46 Australia 29604 T 17126 17125
47 Australia 29605 A 17126 17124
48 Australia 29606 C T 17125 17119 Leu17Phe
49 Australia 29607 T 17124 17121
50 Australia 29608 C 17124 17123
51 Australia 29609 T 17122 17121
52 Australia 29610 T 17122 17120
53 Australia 29611 G 17121 17120
54 Australia 29612 T 17121 17120
55 Australia 29613 G 17121 17120
56 Australia 29614 C T 17121 17076 Cys19Cys
57 Australia 29615 A 17121 17119
58 Australia 29616 G 17121 17120
59 Australia 29617 A 17121 17119
60 Australia 29618 A 17122 17120
61 Australia 29619 T 17122 17118
62 Australia 29620 G 17120 17113
63 Australia 29621 A 17120 17118
64 Australia 29622 A C 17117 17115 Asn22Thr
65 Australia 29623 T 17116 17115
66 Australia 29624 T 17116 17115
67 Australia 29625 C T 17115 17107 Ser23Phe
68 Australia 29626 T C 17115 17113 Ser23Ser
69 Australia 29627 C T 17114 17100 Arg24Cys
70 Australia 29628 G 17116 17111
71 Australia 29629 T 17110 17109
72 Australia 29630 A 17110 17110
73 Australia 29631 A 17110 17110
74 Australia 29632 C T 17110 17106 Asn25Asn
75 Australia 29633 T 17108 17108
76 Australia 29634 A 17107 17107
77 Australia 29635 C T 17107 17100 Tyr26Tyr
78 Australia 29636 A 17106 17106
79 Australia 29637 T 17101 17101
80 Australia 29638 A 17099 17098
81 Australia 29639 G T,C 17092 17087 Ala28Ser-p.Ala28Pro
82 Australia 29640 C 17092 17089
83 Australia 29641 A 17092 17091
84 Australia 29642 C T 17092 17071 Gln29*
85 Australia 29643 A 17091 17090
86 Australia 29644 A 17091 17090
87 Australia 29645 G T 17091 17055 Val30Leu
88 Australia 29646 T 17090 17089
89 Australia 29647 A 17088 17087
90 Australia 29648 G T 17084 17078 Asp31Tyr
91 Australia 29649 A G 17084 17083 Asp31Gly
92 Australia 29650 T 17084 17083
93 Australia 29651 G 17081 17081
94 Australia 29652 T 17081 17081
95 Australia 29653 A G 17079 17078 Val32Val
96 Australia 29654 G A 17077 17076 Val33Ile
97 Australia 29655 T 17075 17075
98 Australia 29656 T 17074 17073
99 Australia 29657 A 17074 17073
100 Australia 29658 A 17074 17074
101 Australia 29659 C 17073 17071
102 Australia 29660 T 17070 17065
103 Australia 29661 T 17064 17064
104 Australia 29662 T 17061 17061
105 Australia 29663 A 17059 17058
106 Australia 29664 A 17058 17058
107 Australia 29665 T 17057 17056
108 Australia 29666 C T 16981 16973 Leu37Phe
109 Australia 29667 T 16973 16972
110 Australia 29668 C T 16969 16967 Leu37Leu
111 Australia 29669 A 16966 16966
112 Australia 29670 C T 16966 16960 Thr38Ile
113 Australia 29671 A 16966 16966
114 Australia 29672 T C 16915 16914 Ter39Glnext*?
115 Australia 29673 A 16908 16907
116 Australia 29674 G 16902 16902