National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  - ? A C D E F G I K L M N P Q R S T V W Y
-   339                                      
?                                          
A   30 4                               2    
C   9                                      
D   18     1     1         1                
E   9       1                              
F   12         1                            
G   27       1   2               1          
I   6             1                        
K   21               1     1                
L   45         1       7                    
M   6             2                        
N   21                                      
P   18                 3           3 1      
Q   12                                      
R   18               2                   1  
S   15                           1 1        
T   36 1           7 1     1                
V   18             3                        
W   3                                      
Y   15                                     1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Netherlands 12686 A 5883 5883
1 Netherlands 12687 A 5883 5883
2 Netherlands 12688 T 5883 5883
3 Netherlands 12689 A 5883 5883
4 Netherlands 12690 A 5883 5883
5 Netherlands 12691 T 5883 5883
6 Netherlands 12692 G 5883 5883
7 Netherlands 12693 A 5883 5883
8 Netherlands 12694 G A 5883 5882 Glu4143Glu
9 Netherlands 12695 C 5883 5883
10 Netherlands 12696 T 5883 5883
11 Netherlands 12697 T 5883 5883
12 Netherlands 12698 A 5883 5883
13 Netherlands 12699 G 5883 5883
14 Netherlands 12700 T 5883 5883
15 Netherlands 12701 C 5883 5883
16 Netherlands 12702 C 5883 5883
17 Netherlands 12703 T 5883 5883
18 Netherlands 12704 G A 5883 5882 Val4147Ile
19 Netherlands 12705 T 5883 5883
20 Netherlands 12706 T 5883 5883
21 Netherlands 12707 G 5883 5883
22 Netherlands 12708 C 5883 5883
23 Netherlands 12709 A 5883 5883
24 Netherlands 12710 C T 5883 5882 Leu4149Leu
25 Netherlands 12711 T 5883 5883
26 Netherlands 12712 A 5883 5883
27 Netherlands 12713 C 5883 5883
28 Netherlands 12714 G 5883 5883
29 Netherlands 12715 A 5883 5883
30 Netherlands 12716 C 5883 5883
31 Netherlands 12717 A 5883 5883
32 Netherlands 12718 G 5883 5883
33 Netherlands 12719 A 5883 5883
34 Netherlands 12720 T 5883 5883
35 Netherlands 12721 G T 5883 5882 Met4152Ile
36 Netherlands 12722 T 5883 5883
37 Netherlands 12723 C 5883 5883
38 Netherlands 12724 T 5883 5883
39 Netherlands 12725 T 5883 5883
40 Netherlands 12726 G 5883 5883
41 Netherlands 12727 T 5883 5883
42 Netherlands 12728 G 5883 5883
43 Netherlands 12729 C 5883 5883
44 Netherlands 12730 T 5883 5883
45 Netherlands 12731 G 5883 5883
46 Netherlands 12732 C 5883 5883
47 Netherlands 12733 C T 5883 5878 Ala4156Ala
48 Netherlands 12734 G 5883 5883
49 Netherlands 12735 G 5883 5883
50 Netherlands 12736 T 5883 5883
51 Netherlands 12737 A 5883 5883
52 Netherlands 12738 C 5883 5883
53 Netherlands 12739 T 5883 5883
54 Netherlands 12740 A 5883 5883
55 Netherlands 12741 C A 5883 5882 Thr4159Lys
56 Netherlands 12742 A 5877 5877
57 Netherlands 12743 C 5877 5877
58 Netherlands 12744 A 5877 5877
59 Netherlands 12745 A 5877 5877
60 Netherlands 12746 A 5877 5877
61 Netherlands 12747 C A,T 5877 5862 Thr4161Asn-p.Thr4161Ile
62 Netherlands 12748 T 5877 5877
63 Netherlands 12749 G 5877 5877
64 Netherlands 12750 C 5877 5877
65 Netherlands 12751 T 5877 5877
66 Netherlands 12752 T 5877 5877
67 Netherlands 12753 G 5877 5877
68 Netherlands 12754 C 5877 5877
69 Netherlands 12755 A 5877 5877
70 Netherlands 12756 C T 5877 5875 Thr4164Ile
71 Netherlands 12757 T 5877 5877
72 Netherlands 12758 G 5877 5877
73 Netherlands 12759 A G 5877 5875 Asp4165Gly
74 Netherlands 12760 T 5877 5877
75 Netherlands 12761 G 5877 5877
76 Netherlands 12762 A 5877 5877
77 Netherlands 12763 C T 5877 5872 Asp4166Asp
78 Netherlands 12764 A 5877 5877
79 Netherlands 12765 A 5876 5876
80 Netherlands 12766 T 5874 5874
81 Netherlands 12767 G 5874 5874
82 Netherlands 12768 C 5874 5874
83 Netherlands 12769 G T 5874 5870 Ala4168Ala
84 Netherlands 12770 T 5874 5874
85 Netherlands 12771 T 5874 5874
86 Netherlands 12772 A 5874 5874
87 Netherlands 12773 G 5873 5873
88 Netherlands 12774 C 5873 5873
89 Netherlands 12775 T 5873 5873
90 Netherlands 12776 T 5873 5873
91 Netherlands 12777 A 5873 5873
92 Netherlands 12778 C 5873 5873
93 Netherlands 12779 T 5873 5873
94 Netherlands 12780 A 5873 5873
95 Netherlands 12781 C T 5873 5864 Tyr4172Tyr
96 Netherlands 12782 A 5873 5873
97 Netherlands 12783 A 5873 5873
98 Netherlands 12784 C 5873 5873
99 Netherlands 12785 A 5873 5873
100 Netherlands 12786 C T 5873 5872 Thr4174Ile
101 Netherlands 12787 A 5873 5873
102 Netherlands 12788 A G 5873 5872 Thr4175Ala
103 Netherlands 12789 C T 5873 5870 Thr4175Ile
104 Netherlands 12790 A 5873 5873
105 Netherlands 12791 A 5873 5873
106 Netherlands 12792 A 5873 5873
107 Netherlands 12793 G T,A 5873 5870 Lys4176Asn-p.Lys4176Lys
108 Netherlands 12794 G A 5873 5798 Gly4177Arg
109 Netherlands 12795 G A 5873 5687 Gly4177Glu
110 Netherlands 12796 A G 5873 5870 Gly4177Gly
111 Netherlands 12797 G 5873 5873
112 Netherlands 12798 G 5873 5873
113 Netherlands 12799 T 5873 5873
114 Netherlands 12800 A 5873 5873
115 Netherlands 12801 G 5873 5873
116 Netherlands 12802 G 5873 5873
117 Netherlands 12803 T 5873 5873
118 Netherlands 12804 T 5873 5873
119 Netherlands 12805 T 5873 5873
120 Netherlands 12806 G A 5873 5872 Val4181Ile
121 Netherlands 12807 T 5873 5873
122 Netherlands 12808 A 5873 5873
123 Netherlands 12809 C T 5873 5862 Leu4182Phe
124 Netherlands 12810 T 5873 5873
125 Netherlands 12811 T 5873 5873
126 Netherlands 12812 G 5873 5873
127 Netherlands 12813 C 5873 5873
128 Netherlands 12814 A 5873 5873
129 Netherlands 12815 C T 5873 5871 Leu4184Leu
130 Netherlands 12816 T 5873 5873
131 Netherlands 12817 G 5873 5873
132 Netherlands 12818 T 5873 5873
133 Netherlands 12819 T 5873 5873
134 Netherlands 12820 A G 5873 5859 Leu4185Leu
135 Netherlands 12821 T 5873 5873
136 Netherlands 12822 C 5873 5873
137 Netherlands 12823 C T 5873 5869 Ser4186Ser
138 Netherlands 12824 G 5873 5873
139 Netherlands 12825 A 5873 5873
140 Netherlands 12826 T 5873 5873
141 Netherlands 12827 T 5873 5873
142 Netherlands 12828 T 5873 5873
143 Netherlands 12829 A 5873 5873
144 Netherlands 12830 C 5873 5873
145 Netherlands 12831 A 5873 5873
146 Netherlands 12832 G 5873 5873
147 Netherlands 12833 G 5873 5873
148 Netherlands 12834 A 5873 5873
149 Netherlands 12835 T 5873 5873
150 Netherlands 12836 T 5873 5873
151 Netherlands 12837 T 5873 5873
152 Netherlands 12838 G 5873 5873
153 Netherlands 12839 A 5873 5873
154 Netherlands 12840 A 5873 5873
155 Netherlands 12841 A 5873 5873
156 Netherlands 12842 T 5873 5873
157 Netherlands 12843 G 5873 5873
158 Netherlands 12844 G 5873 5873
159 Netherlands 12845 G 5873 5873
160 Netherlands 12846 C T 5873 5872 Ala4194Val
161 Netherlands 12847 T 5873 5873
162 Netherlands 12848 A 5873 5873
163 Netherlands 12849 G A 5873 5872 Arg4195Lys
164 Netherlands 12850 A 5873 5873
165 Netherlands 12851 T 5873 5873
166 Netherlands 12852 T 5873 5873
167 Netherlands 12853 C T 5873 5872 Phe4196Phe
168 Netherlands 12854 C T 5873 5871 Pro4197Ser
169 Netherlands 12855 C T 5873 5850 Pro4197Leu
170 Netherlands 12856 T 5873 5873
171 Netherlands 12857 A 5873 5873
172 Netherlands 12858 A 5874 5874
173 Netherlands 12859 G 5874 5874
174 Netherlands 12860 A C 5874 5868 Ser4199Arg
175 Netherlands 12861 G 5874 5874
176 Netherlands 12862 T 5874 5874
177 Netherlands 12863 G A 5874 5873 Asp4200Asn
178 Netherlands 12864 A 5874 5874
179 Netherlands 12865 T 5874 5874
180 Netherlands 12866 G 5874 5874
181 Netherlands 12867 G 5874 5874
182 Netherlands 12868 A 5874 5874
183 Netherlands 12869 A 5874 5874
184 Netherlands 12870 C 5874 5874
185 Netherlands 12871 T 5874 5874
186 Netherlands 12872 G 5874 5874
187 Netherlands 12873 G 5874 5874
188 Netherlands 12874 T 5874 5874
189 Netherlands 12875 A 5874 5874
190 Netherlands 12876 C 5874 5874
191 Netherlands 12877 T 5874 5874
192 Netherlands 12878 A 5874 5874
193 Netherlands 12879 T 5874 5874
194 Netherlands 12880 C T 5874 5869 Ile4205Ile
195 Netherlands 12881 T 5874 5874
196 Netherlands 12882 A 5874 5874
197 Netherlands 12883 T 5873 5873
198 Netherlands 12884 A 5873 5873
199 Netherlands 12885 C T 5873 5872 Thr4207Ile
200 Netherlands 12886 A 5873 5873
201 Netherlands 12887 G 5873 5873
202 Netherlands 12888 A 5873 5873
203 Netherlands 12889 A 5873 5873
204 Netherlands 12890 C 5873 5873
205 Netherlands 12891 T 5873 5872
206 Netherlands 12892 G T,A 5873 5870 Leu4209Leu-p.Leu4209Leu
207 Netherlands 12893 G 5873 5872
208 Netherlands 12894 A 5873 5872
209 Netherlands 12895 A 5873 5872
210 Netherlands 12896 C T 5873 5870 Pro4211Ser
211 Netherlands 12897 C T 5873 5871 Pro4211Leu
212 Netherlands 12898 A 5873 5872
213 Netherlands 12899 C 5873 5872
214 Netherlands 12900 C 5873 5872
215 Netherlands 12901 T 5873 5872
216 Netherlands 12902 T 5873 5872
217 Netherlands 12903 G 5873 5872
218 Netherlands 12904 T 5873 5872
219 Netherlands 12905 A T 5873 5871 Arg4214Trp
220 Netherlands 12906 G A 5873 5871 Arg4214Lys
221 Netherlands 12907 G 5873 5872
222 Netherlands 12908 T 5873 5872
223 Netherlands 12909 T 5873 5872
224 Netherlands 12910 T 5873 5872
225 Netherlands 12911 G 5873 5872
226 Netherlands 12912 T 5873 5872
227 Netherlands 12913 T 5873 5872
228 Netherlands 12914 A 5873 5872
229 Netherlands 12915 C T 5873 5871 Thr4217Ile
230 Netherlands 12916 A 5873 5872
231 Netherlands 12917 G 5873 5872
232 Netherlands 12918 A 5873 5872
233 Netherlands 12919 C 5873 5872
234 Netherlands 12920 A 5873 5872
235 Netherlands 12921 C 5873 5872
236 Netherlands 12922 A 5873 5873
237 Netherlands 12923 C A 5873 5872 Pro4220Thr
238 Netherlands 12924 C 5873 5873
239 Netherlands 12925 T 5873 5873
240 Netherlands 12926 A 5873 5873
241 Netherlands 12927 A 5873 5873
242 Netherlands 12928 A 5873 5873
243 Netherlands 12929 G 5873 5873
244 Netherlands 12930 G 5873 5873
245 Netherlands 12931 T 5873 5873
246 Netherlands 12932 C T 5873 5871 Pro4223Ser
247 Netherlands 12933 C T 5873 5872 Pro4223Leu
248 Netherlands 12934 T 5873 5873
249 Netherlands 12935 A 5873 5873
250 Netherlands 12936 A 5873 5873
251 Netherlands 12937 A 5873 5873
252 Netherlands 12938 G 5873 5873
253 Netherlands 12939 T 5873 5873
254 Netherlands 12940 G 5873 5873
255 Netherlands 12941 A 5873 5873
256 Netherlands 12942 A 5873 5873
257 Netherlands 12943 G 5873 5873
258 Netherlands 12944 T 5873 5873
259 Netherlands 12945 A 5873 5873
260 Netherlands 12946 T 5873 5873
261 Netherlands 12947 T 5873 5873
262 Netherlands 12948 T 5873 5873
263 Netherlands 12949 A G 5873 5872 Leu4228Leu
264 Netherlands 12950 T 5873 5873
265 Netherlands 12951 A 5873 5873
266 Netherlands 12952 C 5873 5873
267 Netherlands 12953 T 5873 5873
268 Netherlands 12954 T 5873 5873
269 Netherlands 12955 T 5873 5873
270 Netherlands 12956 A 5873 5873
271 Netherlands 12957 T 5873 5873
272 Netherlands 12958 T 5873 5873
273 Netherlands 12959 A 5873 5873
274 Netherlands 12960 A 5873 5873
275 Netherlands 12961 A 5873 5873
276 Netherlands 12962 G 5873 5873
277 Netherlands 12963 G 5873 5873
278 Netherlands 12964 A G 5873 5872 Gly4233Gly
279 Netherlands 12965 T 5873 5873
280 Netherlands 12966 T 5873 5873
281 Netherlands 12967 A 5873 5873
282 Netherlands 12968 A 5873 5873
283 Netherlands 12969 A 5873 5873
284 Netherlands 12970 C 5873 5873
285 Netherlands 12971 A 5873 5873
286 Netherlands 12972 A 5873 5873
287 Netherlands 12973 C 5873 5873
288 Netherlands 12974 C 5873 5873
289 Netherlands 12975 T 5873 5873
290 Netherlands 12976 A 5873 5873
291 Netherlands 12977 A 5873 5873
292 Netherlands 12978 A 5873 5873
293 Netherlands 12979 T 5873 5873
294 Netherlands 12980 A 5873 5873
295 Netherlands 12981 G 5873 5873
296 Netherlands 12982 A 5873 5873
297 Netherlands 12983 G 5873 5873
298 Netherlands 12984 G 5873 5873
299 Netherlands 12985 T 5873 5873
300 Netherlands 12986 A 5873 5873
301 Netherlands 12987 T 5873 5873
302 Netherlands 12988 G T 5873 5733 Met4241Ile
303 Netherlands 12989 G A 5873 5870 Val4242Ile
304 Netherlands 12990 T 5873 5873
305 Netherlands 12991 A 5873 5873
306 Netherlands 12992 C 5873 5873
307 Netherlands 12993 T 5873 5873
308 Netherlands 12994 T 5873 5873
309 Netherlands 12995 G 5873 5873
310 Netherlands 12996 G 5873 5873
311 Netherlands 12997 T 5873 5873
312 Netherlands 12998 A 5873 5873
313 Netherlands 12999 G 5873 5873
314 Netherlands 13000 T 5873 5873
315 Netherlands 13001 T 5873 5873
316 Netherlands 13002 T 5873 5873
317 Netherlands 13003 A 5873 5873
318 Netherlands 13004 G 5873 5873
319 Netherlands 13005 C T 5873 5872 Ala4247Val
320 Netherlands 13006 T C 5873 5756 Ala4247Ala
321 Netherlands 13007 G 5873 5873
322 Netherlands 13008 C 5873 5873
323 Netherlands 13009 C T 5873 5871 Ala4248Ala
324 Netherlands 13010 A 5873 5873
325 Netherlands 13011 C T 5873 5837 Thr4249Ile
326 Netherlands 13012 A 5873 5873
327 Netherlands 13013 G 5873 5873
328 Netherlands 13014 T 5873 5873
329 Netherlands 13015 A 5873 5873
330 Netherlands 13016 C 5873 5873
331 Netherlands 13017 G 5873 5873
332 Netherlands 13018 T 5873 5873
333 Netherlands 13019 C T 5873 5872 Leu4252Leu
334 Netherlands 13020 T 5873 5873
335 Netherlands 13021 A 5873 5873
336 Netherlands 13022 C 5873 5873
337 Netherlands 13023 A 5873 5873
338 Netherlands 13024 A 5873 5873