National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  - ? A C D E F G H I K L M N P Q R S T V W Y
-   594                                        
?                                            
A   84 4                             1   8    
C   6                                        
D   39     2                 2                
E   27       3                                
F   15         1                              
G   9                               1        
H                                            
I   30               2                        
K   45                       1                
L   54         2         3                    
M   27                                        
N   39                       3                
P   18                         2     3        
Q   33             1             1 1          
R   21                   1                    
S   45                   1           3       1
T   39 1             6     1 1         2      
V   39         2                         4    
W   6                                        
Y   18                                       1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 France 12092 G 4167 4167
1 France 12093 C 4168 4168
2 France 12094 T 4169 4169
3 France 12095 A 4169 4169
4 France 12096 T 4169 4169
5 France 12097 A 4169 4169
6 France 12098 G 4170 4170
7 France 12099 C 4171 4171
8 France 12100 C T 4171 4169 Ala3945Ala
9 France 12101 T 4171 4169
10 France 12102 C 4171 4167
11 France 12103 A 4171 4169
12 France 12104 G 4172 4171
13 France 12105 A 4172 4171
14 France 12106 G A 4174 4173 Glu3947Glu
15 France 12107 T 4175 4174
16 France 12108 T 4175 4175
17 France 12109 T 4175 4174
18 France 12110 A 4175 4175
19 France 12111 G 4175 4175
20 France 12112 T 4175 4175
21 France 12113 T 4175 4172
22 France 12114 C 4177 4175
23 France 12115 C T 4177 4169 Ser3950Ser
24 France 12116 C T 4178 4171 Leu3951Phe
25 France 12117 T 4178 4175
26 France 12118 T 4180 4177
27 France 12119 C T 4181 4155 Pro3952Ser
28 France 12120 C 4181 4177
29 France 12121 A T 4182 4180 Pro3952Pro
30 France 12122 T 4183 4182
31 France 12123 C 4183 4181
32 France 12124 A G 4185 4181 Ser3953Ser
33 France 12125 T 4185 4182
34 France 12126 A 4185 4183
35 France 12127 T 4185 4182
36 France 12128 G 4185 4182
37 France 12129 C 4185 4183
38 France 12130 A 4185 4181
39 France 12131 G 4190 4186
40 France 12132 C T 4191 4183 Ala3956Val
41 France 12133 T 4193 4189
42 France 12134 T 4193 4187
43 France 12135 T 4193 4189
44 France 12136 T 4193 4188
45 France 12137 G 4193 4189
46 France 12138 C 4193 4188
47 France 12139 T 4193 4188
48 France 12140 A 4193 4187
49 France 12141 C A 4195 4190 Thr3959Asn
50 France 12142 T 4195 4189
51 France 12143 G 4199 4196
52 France 12144 C 4199 4196
53 France 12145 T 4199 4196
54 France 12146 C 4199 4196
55 France 12147 A 4199 4190
56 France 12148 A 4199 4196
57 France 12149 G 4199 4190
58 France 12150 A 4199 4196
59 France 12151 A 4199 4195
60 France 12152 G T 4203 4199 Ala3963Ser
61 France 12153 C T 4205 4202 Ala3963Val
62 France 12154 T 4205 4203
63 France 12155 T 4205 4203
64 France 12156 A 4205 4196
65 France 12157 T 4205 4203
66 France 12158 G 4205 4203
67 France 12159 A 4205 4204
68 France 12160 G A 4205 4197 Glu3965Glu
69 France 12161 C 4203 4201
70 France 12162 A G 4205 4192 Gln3966Arg
71 France 12163 G 4207 4205
72 France 12164 G 4207 4203
73 France 12165 C 4207 4203
74 France 12166 T 4207 4204
75 France 12167 G 4207 4205
76 France 12168 T 4207 4205
77 France 12169 T 4207 4205
78 France 12170 G 4208 4206
79 France 12171 C T 4208 4205 Ala3969Val
80 France 12172 T 4207 4205
81 France 12173 A 4207 4203
82 France 12174 A 4207 4204
83 France 12175 T 4207 4205
84 France 12176 G 4207 4204
85 France 12177 G 4207 4203
86 France 12178 T 4206 4201
87 France 12179 G 4206 4203
88 France 12180 A 4206 4203
89 France 12181 T 4207 4203
90 France 12182 T 4207 4203
91 France 12183 C 4207 4202
92 France 12184 T 4207 4202
93 France 12185 G 4207 4203
94 France 12186 A 4207 4202
95 France 12187 A 4207 4203
96 France 12188 G T 4207 4200 Val3975Phe
97 France 12189 T 4207 4201
98 France 12190 T 4207 4200
99 France 12191 G T 4207 4201 Val3976Phe
100 France 12192 T 4207 4202
101 France 12193 T 4207 4202
102 France 12194 C 4207 4202
103 France 12195 T 4207 4202
104 France 12196 T 4207 4202
105 France 12197 A 4207 4202
106 France 12198 A 4207 4202
107 France 12199 A 4207 4202
108 France 12200 A 4207 4202
109 France 12201 A 4207 4201
110 France 12202 G 4208 4203
111 France 12203 T 4209 4204
112 France 12204 T 4209 4204
113 France 12205 G 4210 4204
114 France 12206 A 4210 4206
115 France 12207 A 4210 4206
116 France 12208 G 4210 4206
117 France 12209 A 4210 4205
118 France 12210 A 4211 4207
119 France 12211 G 4217 4213
120 France 12212 T 4217 4215
121 France 12213 C 4217 4215
122 France 12214 T G 4217 4212 Ser3983Ser
123 France 12215 T 4217 4215
124 France 12216 T 4217 4215
125 France 12217 G 4219 4217
126 France 12218 A 4219 4217
127 France 12219 A 4219 4217
128 France 12220 T 4219 4214
129 France 12221 G 4218 4214
130 France 12222 T 4218 4212
131 France 12223 G T 4220 4213 Val3986Val
132 France 12224 G 4220 4216
133 France 12225 C T 4220 4215 Ala3987Val
134 France 12226 T C 4221 4214 Ala3987Ala
135 France 12227 A 4221 4217
136 France 12228 A 4221 4216
137 France 12229 A 4223 4221
138 France 12230 T 4224 4221
139 France 12231 C 4224 4222
140 France 12232 T 4223 4221
141 France 12233 G 4224 4223
142 France 12234 A 4224 4221
143 France 12235 A G 4224 4222 Glu3990Glu
144 France 12236 T 4224 4222
145 France 12237 T 4224 4222
146 France 12238 T 4224 4223
147 France 12239 G 4224 4223
148 France 12240 A 4224 4223
149 France 12241 C T 4224 4217 Asp3992Asp
150 France 12242 C 4224 4222
151 France 12243 G T 4228 4226 Arg3993Leu
152 France 12244 T 4228 4226
153 France 12245 G 4228 4227
154 France 12246 A 4229 4228
155 France 12247 T 4229 4228
156 France 12248 G 4229 4227
157 France 12249 C 4229 4227
158 France 12250 A 4229 4226
159 France 12251 G 4230 4228
160 France 12252 C 4230 4228
161 France 12253 C 4230 4228
162 France 12254 A 4231 4229
163 France 12255 T 4231 4228
164 France 12256 G 4231 4228
165 France 12257 C 4231 4228
166 France 12258 A 4231 4227
167 France 12259 A 4234 4233
168 France 12260 C 4234 4231
169 France 12261 G 4234 4231
170 France 12262 T 4234 4232
171 France 12263 A 4233 4230
172 France 12264 A 4233 4229
173 France 12265 G 4233 4231
174 France 12266 T 4233 4224
175 France 12267 T 4233 4228
176 France 12268 G 4233 4227
177 France 12269 G 4233 4227
178 France 12270 A 4233 4227
179 France 12271 A 4233 4226
180 France 12272 A 4233 4226
181 France 12273 A 4234 4229
182 France 12274 G 4234 4229
183 France 12275 A 4236 4231
184 France 12276 T 4236 4231
185 France 12277 G 4236 4230
186 France 12278 G 4236 4229
187 France 12279 C 4236 4230
188 France 12280 T 4236 4228
189 France 12281 G 4237 4230
190 France 12282 A 4238 4231
191 France 12283 T 4238 4231
192 France 12284 C 4238 4231
193 France 12285 A 4238 4231
194 France 12286 A 4240 4228
195 France 12287 G 4241 4236
196 France 12288 C 4241 4231
197 France 12289 T 4241 4236
198 France 12290 A 4240 4233
199 France 12291 T 4240 4234
200 France 12292 G 4241 4235
201 France 12293 A 4241 4235
202 France 12294 C 4242 4237
203 France 12295 C T 4241 4235 Thr4010Thr
204 France 12296 C 4241 4235
205 France 12297 A 4241 4237
206 France 12298 A 4241 4237
207 France 12299 A 4241 4237
208 France 12300 T 4247 4244
209 France 12301 G 4249 4247
210 France 12302 T 4249 4245
211 France 12303 A 4249 4243
212 France 12304 T 4249 4242
213 France 12305 A 4249 4243
214 France 12306 A 4249 4243
215 France 12307 A 4249 4243
216 France 12308 C 4249 4243
217 France 12309 A 4247 4237
218 France 12310 G 4252 4243
219 France 12311 G 4252 4243
220 France 12312 C T 4252 4242 Ala4016Val
221 France 12313 T 4252 4244
222 France 12314 A 4252 4243
223 France 12315 G 4255 4248
224 France 12316 A 4255 4248
225 France 12317 T 4255 4249
226 France 12318 C A 4255 4248 Ser4018Tyr
227 France 12319 T 4255 4247
228 France 12320 G 4257 4251
229 France 12321 A 4257 4251
230 France 12322 G 4257 4251
231 France 12323 G 4257 4251
232 France 12324 A 4256 4250
233 France 12325 C 4256 4248
234 France 12326 A 4256 4247
235 France 12327 A 4256 4248
236 France 12328 G 4256 4248
237 France 12329 A 4256 4247
238 France 12330 G 4258 4248
239 France 12331 G 4258 4249
240 France 12332 G 4258 4248
241 France 12333 C T 4259 4249 Ala4023Val
242 France 12334 A T 4259 4241 Ala4023Ala
243 France 12335 A 4259 4248
244 France 12336 A 4259 4249
245 France 12337 A 4259 4250
246 France 12338 G 4260 4251
247 France 12339 T 4260 4251
248 France 12340 T 4261 4255
249 France 12341 A 4261 4255
250 France 12342 C T 4261 4253 Thr4026Ile
251 France 12343 T 4261 4255
252 France 12344 A 4261 4254
253 France 12345 G 4265 4261
254 France 12346 T 4264 4260
255 France 12347 G 4265 4261
256 France 12348 C 4265 4261
257 France 12349 T 4264 4255
258 France 12350 A 4265 4259
259 France 12351 T 4264 4258
260 France 12352 G 4264 4258
261 France 12353 C 4263 4257
262 France 12354 A 4262 4254
263 France 12355 G 4262 4253
264 France 12356 A 4262 4254
265 France 12357 C T 4262 4253 Thr4031Ile
266 France 12358 A G 4262 4252 Thr4031Thr
267 France 12359 A 4262 4253
268 France 12360 T 4262 4252
269 France 12361 G 4263 4254
270 France 12362 C 4263 4254
271 France 12363 T 4263 4252
272 France 12364 T 4263 4252
273 France 12365 T 4263 4252
274 France 12366 T 4263 4255
275 France 12367 C T 4263 4249 Phe4034Phe
276 France 12368 A 4263 4254
277 France 12369 C 4263 4255
278 France 12370 T 4263 4251
279 France 12371 A 4263 4252
280 France 12372 T 4263 4251
281 France 12373 G 4264 4258
282 France 12374 C 4264 4257
283 France 12375 T 4264 4256
284 France 12376 T 4264 4257
285 France 12377 A 4264 4257
286 France 12378 G 4264 4258
287 France 12379 A 4264 4258
288 France 12380 A 4263 4257
289 France 12381 A 4263 4257
290 France 12382 G 4263 4259
291 France 12383 T 4263 4258
292 France 12384 T 4263 4259
293 France 12385 G T 4263 4257 Leu4040Phe
294 France 12386 G A 4264 4259 Asp4041Asn
295 France 12387 A 4265 4261
296 France 12388 T 4265 4261
297 France 12389 A 4265 4261
298 France 12390 A 4265 4262
299 France 12391 T 4265 4260
300 France 12392 G 4265 4260
301 France 12393 A 4265 4258
302 France 12394 T 4264 4259
303 France 12395 G 4265 4260
304 France 12396 C 4263 4258
305 France 12397 A 4263 4258
306 France 12398 C 4264 4259
307 France 12399 T 4264 4259
308 France 12400 C T 4265 4260 Leu4045Leu
309 France 12401 A 4265 4262
310 France 12402 A 4265 4262
311 France 12403 C 4265 4263
312 France 12404 A 4265 4262
313 France 12405 A 4265 4264
314 France 12406 C 4265 4264
315 France 12407 A 4265 4262
316 France 12408 T 4265 4262
317 France 12409 T 4264 4260
318 France 12410 A 4264 4259
319 France 12411 T 4263 4258
320 France 12412 C T 4263 4252 Ile4049Ile
321 France 12413 A 4263 4256
322 France 12414 A 4263 4257
323 France 12415 C T 4263 4255 Asn4050Asn
324 France 12416 A 4262 4254
325 France 12417 A 4262 4252
326 France 12418 T 4262 4256
327 France 12419 G 4262 4257
328 France 12420 C 4262 4251
329 France 12421 A 4262 4257
330 France 12422 A 4262 4257
331 France 12423 G 4262 4258
332 France 12424 A 4262 4257
333 France 12425 G 4262 4257
334 France 12426 A 4259 4252
335 France 12427 T 4259 4252
336 France 12428 G 4259 4253
337 France 12429 G 4259 4252
338 France 12430 T 4259 4253
339 France 12431 T 4258 4251
340 France 12432 G 4258 4250
341 France 12433 T 4256 4248
342 France 12434 G 4256 4248
343 France 12435 T 4256 4248
344 France 12436 T C,A 4256 4245 Val4057Val-p.Val4057Val
345 France 12437 C 4257 4252
346 France 12438 C 4256 4250
347 France 12439 C T 4257 4247 Pro4058Pro
348 France 12440 T 4257 4251
349 France 12441 T 4257 4251
350 France 12442 G 4257 4252
351 France 12443 A 4258 4252
352 France 12444 A 4259 4255
353 France 12445 C T 4259 4255 Asn4060Asn
354 France 12446 A 4255 4251
355 France 12447 T 4255 4251
356 France 12448 A 4255 4251
357 France 12449 A 4255 4251
358 France 12450 T 4255 4249
359 France 12451 A 4254 4245
360 France 12452 C 4255 4248
361 France 12453 C 4251 4244
362 France 12454 T 4252 4245
363 France 12455 C 4252 4247
364 France 12456 T 4251 4246
365 France 12457 T 4252 4248
366 France 12458 A 4252 4248
367 France 12459 C T 4251 4244 Thr4065Ile
368 France 12460 A 4251 4247
369 France 12461 A 4252 4248
370 France 12462 C 4252 4248
371 France 12463 A 4248 4244
372 France 12464 G 4248 4243
373 France 12465 C 4247 4241
374 France 12466 A 4247 4242
375 France 12467 G 4247 4243
376 France 12468 C 4247 4241
377 France 12469 C T 4247 4239 Ala4068Ala
378 France 12470 A 4247 4241
379 France 12471 A 4247 4241
380 France 12472 A 4247 4242
381 France 12473 C T 4247 4241 Leu4070Leu
382 France 12474 T 4247 4242
383 France 12475 A 4247 4243
384 France 12476 A 4247 4243
385 France 12477 T 4247 4243
386 France 12478 G 4247 4243
387 France 12479 G 4247 4243
388 France 12480 T 4247 4240
389 France 12481 T 4246 4240
390 France 12482 G 4245 4239
391 France 12483 T 4245 4236
392 France 12484 C T 4245 4235 Val4073Val
393 France 12485 A 4245 4238
394 France 12486 T 4245 4236
395 France 12487 A 4245 4238
396 France 12488 C T 4245 4221 Pro4075Ser
397 France 12489 C 4245 4234
398 France 12490 A 4244 4231
399 France 12491 G 4243 4234
400 France 12492 A 4243 4234
401 France 12493 C 4243 4237
402 France 12494 T 4243 4237
403 France 12495 A 4243 4236
404 France 12496 T C 4243 4233 Tyr4077Tyr
405 France 12497 A 4243 4236
406 France 12498 A 4243 4236
407 France 12499 C 4243 4236
408 France 12500 A 4242 4232
409 France 12501 C 4242 4233
410 France 12502 A 4233 4220
411 France 12503 T 4233 4219
412 France 12504 A 4233 4220
413 France 12505 T 4233 4221
414 France 12506 A 4233 4221
415 France 12507 A 4233 4221
416 France 12508 A T 4232 4220 Lys4081Asn
417 France 12509 A 4232 4221
418 France 12510 A 4232 4221
419 France 12511 T C 4232 4221 Asn4082Asn
420 France 12512 A 4232 4221
421 France 12513 C T 4232 4213 Thr4083Met
422 France 12514 G 4232 4223
423 France 12515 T 4232 4222
424 France 12516 G 4232 4223
425 France 12517 T 4231 4223
426 France 12518 G 4231 4219
427 France 12519 A 4230 4222
428 France 12520 T 4230 4222
429 France 12521 G A 4230 4221 Gly4086Ser
430 France 12522 G 4230 4225
431 France 12523 T 4230 4223
432 France 12524 A 4230 4224
433 France 12525 C T 4230 4218 Thr4087Ile
434 France 12526 A 4230 4224
435 France 12527 A 4231 4227
436 France 12528 C T 4231 4225 Thr4088Ile
437 France 12529 A 4229 4226
438 France 12530 T 4228 4223
439 France 12531 T 4225 4218
440 France 12532 T 4225 4219
441 France 12533 A G 4225 4168 Thr4090Ala
442 France 12534 C T 4225 4217 Thr4090Ile
443 France 12535 T 4223 4214
444 France 12536 T 4223 4214
445 France 12537 A 4224 4214
446 France 12538 T 4222 4213
447 France 12539 G 4222 4213
448 France 12540 C 4222 4216
449 France 12541 A 4222 4216
450 France 12542 T 4222 4215
451 France 12543 C 4222 4216
452 France 12544 A 4222 4216
453 France 12545 G 4222 4217
454 France 12546 C 4222 4218
455 France 12547 A 4222 4217
456 France 12548 T 4222 4217
457 France 12549 T 4221 4216
458 France 12550 G 4221 4216
459 France 12551 T 4219 4214
460 France 12552 G 4219 4214
461 France 12553 G 4219 4214
462 France 12554 G 4219 4213
463 France 12555 A 4219 4212
464 France 12556 A 4218 4212
465 France 12557 A 4217 4211
466 France 12558 T 4218 4212
467 France 12559 C T 4218 4184 Ile4098Ile
468 France 12560 C 4217 4212
469 France 12561 A 4216 4211
470 France 12562 A 4216 4211
471 France 12563 C 4216 4210
472 France 12564 A 4215 4210
473 France 12565 G T,A 4215 4207 Gln4100His-p.Gln4100Gln
474 France 12566 G 4214 4210
475 France 12567 T 4214 4209
476 France 12568 T 4214 4210
477 France 12569 G 4214 4210
478 France 12570 T 4214 4210
479 France 12571 A 4214 4210
480 France 12572 G 4214 4211
481 France 12573 A 4214 4211
482 France 12574 T 4211 4208
483 France 12575 G 4211 4208
484 France 12576 C 4211 4208
485 France 12577 A 4211 4207
486 France 12578 G 4211 4204
487 France 12579 A 4209 4205
488 France 12580 T 4210 4204
489 France 12581 A 4210 4208
490 France 12582 G 4210 4208
491 France 12583 T 4210 4208
492 France 12584 A 4210 4207
493 France 12585 A 4209 4207
494 France 12586 A 4209 4206
495 France 12587 A 4209 4206
496 France 12588 T 4209 4206
497 France 12589 T 4207 4203
498 France 12590 G 4207 4204
499 France 12591 T 4206 4203
500 France 12592 T 4206 4202
501 France 12593 C 4206 4202
502 France 12594 A 4206 4203
503 France 12595 A 4206 4202
504 France 12596 C 4206 4203
505 France 12597 T 4205 4202
506 France 12598 T 4205 4202
507 France 12599 A 4205 4202
508 France 12600 G 4205 4202
509 France 12601 T 4205 4202
510 France 12602 G 4205 4202
511 France 12603 A 4205 4202
512 France 12604 A 4203 4197
513 France 12605 A 4203 4198
514 France 12606 T 4202 4198
515 France 12607 T 4202 4198
516 France 12608 A 4203 4200
517 France 12609 G 4203 4200
518 France 12610 T 4203 4200
519 France 12611 A 4203 4200
520 France 12612 T 4202 4199
521 France 12613 G 4202 4198
522 France 12614 G A 4202 4196 Asp4117Asn
523 France 12615 A 4202 4199
524 France 12616 C T 4201 4197 Asp4117Asp
525 France 12617 A 4200 4196
526 France 12618 A 4200 4195
527 France 12619 T 4200 4196
528 France 12620 T 4198 4194
529 France 12621 C T 4198 4192 Ser4119Leu
530 France 12622 A 4198 4194
531 France 12623 C T 4198 4193 Pro4120Ser
532 France 12624 C 4198 4194
533 France 12625 T 4198 4194
534 France 12626 A 4198 4197
535 France 12627 A 4198 4197
536 France 12628 T 4198 4197
537 France 12629 T 4198 4196
538 France 12630 T 4198 4197
539 France 12631 A 4196 4195
540 France 12632 G 4196 4195
541 France 12633 C 4196 4195
542 France 12634 A 4196 4195
543 France 12635 T 4194 4193
544 France 12636 G 4194 4192
545 France 12637 G 4194 4192
546 France 12638 C 4194 4193
547 France 12639 C 4194 4193
548 France 12640 T 4193 4191
549 France 12641 C 4192 4191
550 France 12642 T 4191 4190
551 France 12643 T 4191 4190
552 France 12644 A 4191 4190
553 France 12645 T 4191 4191
554 France 12646 T 4191 4190
555 France 12647 G 4191 4190
556 France 12648 T 4191 4190
557 France 12649 A 4191 4190
558 France 12650 A 4191 4190
559 France 12651 C 4191 4190
560 France 12652 A 4190 4189
561 France 12653 G 4190 4190
562 France 12654 C 4190 4190
563 France 12655 T 4190 4190
564 France 12656 T C 4189 4188 Leu4131Leu
565 France 12657 T 4189 4188
566 France 12658 A 4189 4189
567 France 12659 A 4189 4189
568 France 12660 G 4189 4189
569 France 12661 G 4189 4189
570 France 12662 G 4188 4188
571 France 12663 C T 4187 4185 Ala4133Val
572 France 12664 C 4187 4187
573 France 12665 A 4187 4187
574 France 12666 A 4187 4187
575 France 12667 T 4187 4187
576 France 12668 T 4187 4187
577 France 12669 C 4187 4187
578 France 12670 T 4186 4186
579 France 12671 G 4186 4186
580 France 12672 C T 4186 4182 Ala4136Val
581 France 12673 T 4184 4184
582 France 12674 G 4184 4184
583 France 12675 T 4184 4184
584 France 12676 C 4184 4184
585 France 12677 A 4184 4184
586 France 12678 A 4184 4184
587 France 12679 A 4183 4183
588 France 12680 T 4182 4182
589 France 12681 T 4182 4182
590 France 12682 A 4182 4182
591 France 12683 C 4182 4182
592 France 12684 A 4181 4181
593 France 12685 G 4181 4181