National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.
Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P Q R S T V W Y
*                                              
-     249                                        
?                                              
A     15 3                                      
C     9   1                                   1
D     15     3       1                          
E     15           1                       1    
F     3                                        
G     3   1                                    
H     3             1                          
I     6               1                        
K     18       1         2           1          
L     45         3         16                    
M     12                                        
N     9                       1                
P                                              
Q 1   18                           1            
R     6                             1          
S     30                   1     1     5        
T     12                         1       3      
V     27                                   6    
W     3                                        
Y                                              

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 China 11843 T 932 932
1 China 11844 C 932 932
2 China 11845 T 932 931
3 China 11846 A 932 932
4 China 11847 A 932 932
5 China 11848 A 932 932
6 China 11849 A 932 932
7 China 11850 T 932 932
8 China 11851 G 932 932
9 China 11852 T 932 932
10 China 11853 C 932 932
11 China 11854 A T 932 931 Ser3863Ser
12 China 11855 G 932 932
13 China 11856 A 932 932
14 China 11857 T 932 932
15 China 11858 G 932 932
16 China 11859 T 932 932
17 China 11860 A 932 932
18 China 11861 A 932 932
19 China 11862 A G 932 931 Lys3866Arg
20 China 11863 G 932 932
21 China 11864 T 932 932
22 China 11865 G 932 932
23 China 11866 C T 932 926 Cys3867Cys
24 China 11867 A 932 932
25 China 11868 C 932 932
26 China 11869 A G 932 925 Thr3868Thr
27 China 11870 T 933 932
28 China 11871 C 933 933
29 China 11872 A T 933 932 Ser3869Ser
30 China 11873 G 933 933
31 China 11874 T 933 933
32 China 11875 A G 933 932 Val3870Val
33 China 11876 G 933 933
34 China 11877 T 933 933
35 China 11878 C T,A 933 926 Val3871Val-p.Val3871Val
36 China 11879 T C 933 932 Leu3872Leu
37 China 11880 T 934 934
38 China 11881 A T 934 933 Leu3872Phe
39 China 11882 C 934 934
40 China 11883 T 934 934
41 China 11884 C T 934 927 Leu3873Leu
42 China 11885 T 934 934
43 China 11886 C 934 934
44 China 11887 A 934 934
45 China 11888 G 934 934
46 China 11889 T 934 934
47 China 11890 T 937 937
48 China 11891 T C 937 936 Leu3876Leu
49 China 11892 T 937 937
50 China 11893 G A,C 937 930 Leu3876Phe-p.Leu3876Leu
51 China 11894 C 937 937
52 China 11895 A 937 937
53 China 11896 A 937 937
54 China 11897 C T 937 931 Gln3878*
55 China 11898 A 937 937
56 China 11899 A 937 937
57 China 11900 C 937 937
58 China 11901 T 937 937
59 China 11902 C T 937 929 Leu3879Leu
60 China 11903 A 937 937
61 China 11904 G 937 937
62 China 11905 A 937 937
63 China 11906 G 937 937
64 China 11907 T 937 937
65 China 11908 A 937 937
66 China 11909 G 937 937
67 China 11910 A G 937 936 Glu3882Gly
68 China 11911 A 937 937
69 China 11912 T 937 936
70 China 11913 C 937 937
71 China 11914 A G 937 931 Ser3883Ser
72 China 11915 T 937 937
73 China 11916 C T 937 935 Ser3884Leu
74 China 11917 A T 937 930 Ser3884Ser
75 China 11918 T 937 937
76 China 11919 C 937 937
77 China 11920 T 937 937
78 China 11921 A 937 937
79 China 11922 A 937 937
80 China 11923 A 937 937
81 China 11924 T 937 937
82 China 11925 T 937 937
83 China 11926 G 937 937
84 China 11927 T 937 937
85 China 11928 G 938 938
86 China 11929 G 938 938
87 China 11930 G 938 938
88 China 11931 C 938 938
89 China 11932 T G 938 937 Ala3889Ala
90 China 11933 C 938 938
91 China 11934 A 938 938
92 China 11935 A 938 938
93 China 11936 T 938 938
94 China 11937 G A 938 937 Cys3891Tyr
95 China 11938 T 938 938
96 China 11939 G 938 938
97 China 11940 T 938 938
98 China 11941 C T 937 929 Val3892Val
99 China 11942 C 937 937
100 China 11943 A 937 937
101 China 11944 G 937 937
102 China 11945 T C 937 931 Leu3894Leu
103 China 11946 T 937 937
104 China 11947 A C 937 931 Leu3894Phe
105 China 11948 C 937 937
106 China 11949 A 937 937
107 China 11950 C T 937 931 His3895His
108 China 11951 A 937 937
109 China 11952 A 937 937
110 China 11953 T 937 937
111 China 11954 G 937 937
112 China 11955 A 937 937
113 China 11956 C T 937 930 Asp3897Asp
114 China 11957 A 937 937
115 China 11958 T 937 937
116 China 11959 T A 937 936 Ile3898Ile
117 China 11960 C 937 937
118 China 11961 T 938 938
119 China 11962 C T 938 937 Leu3899Leu
120 China 11963 T 938 938
121 China 11964 T 939 939
122 China 11965 A 939 939
123 China 11966 G 939 939
124 China 11967 C 939 939
125 China 11968 T A 939 938 Ala3901Ala
126 China 11969 A G 939 938 Lys3902Glu
127 China 11970 A 939 939
128 China 11971 A G 939 932 Lys3902Lys
129 China 11972 G 940 940
130 China 11973 A 940 940
131 China 11974 T C 940 939 Asp3903Asp
132 China 11975 A 940 940
133 China 11976 C 940 940
134 China 11977 T 940 940
135 China 11978 A C 946 945 Thr3905Pro
136 China 11979 C 945 945
137 China 11980 T 945 945
138 China 11981 G 945 945
139 China 11982 A T 945 944 Glu3906Val
140 China 11983 A 945 945
141 China 11984 G 945 945
142 China 11985 C 945 945
143 China 11986 C A 945 938 Ala3907Ala
144 China 11987 T 945 945
145 China 11988 T 945 945
146 China 11989 T 945 945
147 China 11990 G 945 945
148 China 11991 A 945 945
149 China 11992 A 945 944
150 China 11993 A 945 945
151 China 11994 A 945 945
152 China 11995 A 945 945
153 China 11996 A 945 944
154 China 11997 T 945 945
155 China 11998 G 945 945
156 China 11999 G 945 945
157 China 12000 T 945 945
158 China 12001 T 945 945
159 China 12002 T 945 945
160 China 12003 C 945 945
161 China 12004 A 945 945
162 China 12005 C T 945 932 Leu3914Leu
163 China 12006 T 945 945
164 China 12007 A 945 945
165 China 12008 C 945 945
166 China 12009 T 945 945
167 China 12010 T G 945 938 Leu3915Leu
168 China 12011 T C 945 944 Ser3916Pro
169 China 12012 C 945 945
170 China 12013 T 945 945
171 China 12014 G 945 945
172 China 12015 T 945 945
173 China 12016 T G,C 945 936 Val3917Val-p.Val3917Val
174 China 12017 T C 945 938 Leu3918Leu
175 China 12018 T 945 945
176 China 12019 G A 945 944 Leu3918Leu
177 China 12020 C 945 945
178 China 12021 T 945 945
179 China 12022 T A 945 938 Leu3919Leu
180 China 12023 T 945 945
181 China 12024 C 945 945
182 China 12025 C T 945 938 Ser3920Ser
183 China 12026 A 945 945
184 China 12027 T 945 945
185 China 12028 G 945 945
186 China 12029 C 945 945
187 China 12030 A 945 945
188 China 12031 G A 945 931 Gln3922Gln
189 China 12032 G T 945 944 Gly3923Cys
190 China 12033 G 945 945
191 China 12034 T 945 944
192 China 12035 G 945 945
193 China 12036 C 945 945
194 China 12037 T 945 945
195 China 12038 G 945 945
196 China 12039 T 945 945
197 China 12040 A 945 945
198 China 12041 G C 945 944 Asp3926His
199 China 12042 A 945 945
200 China 12043 C 945 945
201 China 12044 A 945 945
202 China 12045 T 945 945
203 China 12046 A 945 945
204 China 12047 A 945 945
205 China 12048 A 945 945
206 China 12049 C 945 945
207 China 12050 A 945 945
208 China 12051 A 945 945
209 China 12052 G A 945 939 Lys3929Lys
210 China 12053 C 945 945
211 China 12054 T 945 945
212 China 12055 T C 945 939 Leu3930Leu
213 China 12056 T 945 945
214 China 12057 G 945 945
215 China 12058 T 945 945
216 China 12059 G 945 945
217 China 12060 A 945 945
218 China 12061 A 945 945
219 China 12062 G 945 945
220 China 12063 A 945 944
221 China 12064 A 945 945
222 China 12065 A 945 945
223 China 12066 T 945 945
224 China 12067 G 945 945
225 China 12068 C T 945 938 Leu3935Leu
226 China 12069 T 945 945
227 China 12070 G C,T 945 936 Leu3935Leu-p.Leu3935Leu
228 China 12071 G 945 945
229 China 12072 A 945 945
230 China 12073 C T 945 937 Asp3936Asp
231 China 12074 A 945 945
232 China 12075 A 945 945
233 China 12076 C T 945 944 Asn3937Asn
234 China 12077 A 945 945
235 China 12078 G 945 945
236 China 12079 G A 945 938 Arg3938Arg
237 China 12080 G 945 945
238 China 12081 C 945 945
239 China 12082 A 945 945
240 China 12083 A 945 945
241 China 12084 C 945 945
242 China 12085 C A,T 945 937 Thr3940Thr-p.Thr3940Thr
243 China 12086 T 945 945
244 China 12087 T 944 944
245 China 12088 A 944 944
246 China 12089 C 944 944
247 China 12090 A 944 944
248 China 12091 A 937 937