National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  - ? A C D E F G H I K L M N P Q R S T V W Y
-   540                                        
?                                            
A   21                                        
C   3                                        
D   27                                        
E   54     1 1   1     2                      
F   15         1                              
G   66   1       3                       1    
H   21                             2         2
I   9                                        
K   27                                        
L   63         2         3                    
M   9                                        
N   18                       1       1        
P   24                         1              
Q   21                                        
R   30   1                                    
S   30                   1         1 1        
T   21                                        
V   63 1                                 4    
W   3                                        
Y   15                                        

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Peru 266 A 528 528
1 Peru 267 T 528 528
2 Peru 268 G 528 528
3 Peru 269 G A 528 527 Glu2Lys
4 Peru 270 A 528 528
5 Peru 271 G 528 528
6 Peru 272 A 528 528
7 Peru 273 G 528 528
8 Peru 274 C T 528 527 Ser3Ser
9 Peru 275 C 528 528
10 Peru 276 T 528 528
11 Peru 277 T 528 528
12 Peru 278 G 528 528
13 Peru 279 T 528 528
14 Peru 280 C T 528 527 Val5Val
15 Peru 281 C 528 528
16 Peru 282 C 528 528
17 Peru 283 T 528 528
18 Peru 284 G 528 528
19 Peru 285 G 528 528
20 Peru 286 T 528 528
21 Peru 287 T 528 528
22 Peru 288 T 528 528
23 Peru 289 C 528 528
24 Peru 290 A 528 528
25 Peru 291 A 528 528
26 Peru 292 C 528 528
27 Peru 293 G 528 528
28 Peru 294 A 528 528
29 Peru 295 G 528 528
30 Peru 296 A 528 528
31 Peru 297 A 528 528
32 Peru 298 A 528 528
33 Peru 299 A 528 528
34 Peru 300 C 528 528
35 Peru 301 A 528 528
36 Peru 302 C 528 528
37 Peru 303 A 528 528
38 Peru 304 C 528 528
39 Peru 305 G 528 528
40 Peru 306 T 528 528
41 Peru 307 C 528 528
42 Peru 308 C 528 528
43 Peru 309 A 528 528
44 Peru 310 A 528 528
45 Peru 311 C 528 528
46 Peru 312 T 528 528
47 Peru 313 C T 528 525 Leu16Leu
48 Peru 314 A C 528 527 Ser17Arg
49 Peru 315 G 528 528
50 Peru 316 T 528 528
51 Peru 317 T 528 528
52 Peru 318 T 528 528
53 Peru 319 G 528 528
54 Peru 320 C 528 528
55 Peru 321 C 528 528
56 Peru 322 T 528 528
57 Peru 323 G 528 528
58 Peru 324 T 528 528
59 Peru 325 T 528 528
60 Peru 326 T 528 528
61 Peru 327 T 528 528
62 Peru 328 A 528 528
63 Peru 329 C 528 528
64 Peru 330 A 528 528
65 Peru 331 G 528 528
66 Peru 332 G 528 528
67 Peru 333 T 528 528
68 Peru 334 T 528 528
69 Peru 335 C T 528 526 Arg24Cys
70 Peru 336 G 528 528
71 Peru 337 C 528 528
72 Peru 338 G 528 528
73 Peru 339 A 528 528
74 Peru 340 C 528 528
75 Peru 341 G 528 528
76 Peru 342 T C 528 527 Val26Ala
77 Peru 343 G 528 528
78 Peru 344 C T 528 527 Leu27Phe
79 Peru 345 T 528 528
80 Peru 346 C T 528 527 Leu27Leu
81 Peru 347 G 528 528
82 Peru 348 T 528 528
83 Peru 349 A 528 528
84 Peru 350 C 528 528
85 Peru 351 G 528 528
86 Peru 352 T 528 528
87 Peru 353 G 528 528
88 Peru 354 G 528 528
89 Peru 355 C 528 528
90 Peru 356 T 528 528
91 Peru 357 T 528 528
92 Peru 358 T 528 528
93 Peru 359 G 528 528
94 Peru 360 G 528 528
95 Peru 361 A 528 528
96 Peru 362 G 528 528
97 Peru 363 A 528 528
98 Peru 364 C 528 528
99 Peru 365 T 528 528
100 Peru 366 C 528 528
101 Peru 367 C 528 528
102 Peru 368 G 528 528
103 Peru 369 T 528 528
104 Peru 370 G 528 528
105 Peru 371 G 528 528
106 Peru 372 A 528 528
107 Peru 373 G T 528 527 Glu36Asp
108 Peru 374 G 528 528
109 Peru 375 A 528 528
110 Peru 376 G 528 528
111 Peru 377 G 528 528
112 Peru 378 T 528 528
113 Peru 379 C T 528 526 Val38Val
114 Peru 380 T 528 528
115 Peru 381 T 528 528
116 Peru 382 A 528 528
117 Peru 383 T 528 528
118 Peru 384 C 528 528
119 Peru 385 A 528 528
120 Peru 386 G 528 528
121 Peru 387 A 528 528
122 Peru 388 G 528 528
123 Peru 389 G 528 528
124 Peru 390 C 528 528
125 Peru 391 A 528 528
126 Peru 392 C 528 528
127 Peru 393 G 528 528
128 Peru 394 T 528 528
129 Peru 395 C 528 528
130 Peru 396 A 528 528
131 Peru 397 A 528 528
132 Peru 398 C T 528 527 His45Tyr
133 Peru 399 A G 528 527 His45Arg
134 Peru 400 T 528 528
135 Peru 401 C 528 528
136 Peru 402 T 528 528
137 Peru 403 T 528 528
138 Peru 404 A 528 528
139 Peru 405 A 528 528
140 Peru 406 A 528 526
141 Peru 407 G 528 528
142 Peru 408 A 528 528
143 Peru 409 T 528 528
144 Peru 410 G 528 528
145 Peru 411 G 528 528
146 Peru 412 C 528 528
147 Peru 413 A 528 528
148 Peru 414 C 528 528
149 Peru 415 T 528 528
150 Peru 416 T 528 528
151 Peru 417 G 528 528
152 Peru 418 T 528 528
153 Peru 419 G 528 528
154 Peru 420 G 528 528
155 Peru 421 C 528 528
156 Peru 422 T 528 528
157 Peru 423 T 528 528
158 Peru 424 A 528 528
159 Peru 425 G 528 528
160 Peru 426 T 528 528
161 Peru 427 A 528 528
162 Peru 428 G 528 528
163 Peru 429 A 528 528
164 Peru 430 A 528 528
165 Peru 431 G 528 528
166 Peru 432 T 528 528
167 Peru 433 T 528 528
168 Peru 434 G 528 528
169 Peru 435 A 528 528
170 Peru 436 A 528 528
171 Peru 437 A 528 528
172 Peru 438 A 528 528
173 Peru 439 A 528 528
174 Peru 440 G 528 528
175 Peru 441 G 528 528
176 Peru 442 C T 528 525 Gly59Gly
177 Peru 443 G 528 528
178 Peru 444 T 528 528
179 Peru 445 T C 528 525 Val60Val
180 Peru 446 T 528 528
181 Peru 447 T 528 528
182 Peru 448 G T 528 527 Leu61Phe
183 Peru 449 C 528 528
184 Peru 450 C 528 528
185 Peru 451 T 528 528
186 Peru 452 C 528 528
187 Peru 453 A 528 528
188 Peru 454 A 528 528
189 Peru 455 C 528 528
190 Peru 456 T 528 528
191 Peru 457 T 528 528
192 Peru 458 G 528 528
193 Peru 459 A 528 528
194 Peru 460 A 528 528
195 Peru 461 C 528 528
196 Peru 462 A 528 528
197 Peru 463 G 528 528
198 Peru 464 C 528 528
199 Peru 465 C 528 528
200 Peru 466 C T 528 527 Pro67Pro
201 Peru 467 T 528 528
202 Peru 468 A 528 528
203 Peru 469 T 528 528
204 Peru 470 G 528 528
205 Peru 471 T 528 528
206 Peru 472 G 528 528
207 Peru 473 T 528 528
208 Peru 474 T 528 528
209 Peru 475 C T 528 527 Phe70Phe
210 Peru 476 A 528 528
211 Peru 477 T 528 528
212 Peru 478 C 528 528
213 Peru 479 A 528 528
214 Peru 480 A 528 528
215 Peru 481 A 528 528
216 Peru 482 C 528 528
217 Peru 483 G 528 528
218 Peru 484 T 528 528
219 Peru 485 T 528 528
220 Peru 486 C 528 528
221 Peru 487 G 528 528
222 Peru 488 G 528 528
223 Peru 489 A 528 528
224 Peru 490 T 528 528
225 Peru 491 G 528 528
226 Peru 492 C 528 528
227 Peru 493 T 528 528
228 Peru 494 C 528 528
229 Peru 495 G 528 528
230 Peru 496 A 528 528
231 Peru 497 A 528 528
232 Peru 498 C 528 528
233 Peru 499 T 528 528
234 Peru 500 G 528 528
235 Peru 501 C 528 528
236 Peru 502 A 528 528
237 Peru 503 C 528 528
238 Peru 504 C 528 528
239 Peru 505 T 526 526
240 Peru 506 C 526 526
241 Peru 507 A 526 526
242 Peru 508 T 526 526
243 Peru 509 G 526 526
244 Peru 510 G 526 525
245 Peru 511 T 526 525
246 Peru 512 C 526 525
247 Peru 513 A G 526 524 His83Arg
248 Peru 514 T 526 525
249 Peru 515 G 526 525
250 Peru 516 T 526 525
251 Peru 517 T 526 525
252 Peru 518 A 526 525
253 Peru 519 T 526 526
254 Peru 520 G 526 526
255 Peru 521 G 526 526
256 Peru 522 T 526 526
257 Peru 523 T 526 526
258 Peru 524 G 526 526
259 Peru 525 A 526 526
260 Peru 526 G 526 526
261 Peru 527 C 526 526
262 Peru 528 T 526 526
263 Peru 529 G 526 526
264 Peru 530 G 526 526
265 Peru 531 T 526 526
266 Peru 532 A 526 526
267 Peru 533 G 526 526
268 Peru 534 C 526 526
269 Peru 535 A 526 526
270 Peru 536 G 526 526
271 Peru 537 A 526 526
272 Peru 538 A 526 526
273 Peru 539 C 526 526
274 Peru 540 T 526 526
275 Peru 541 C 526 526
276 Peru 542 G 526 526
277 Peru 543 A G 526 525 Glu93Gly
278 Peru 544 A 526 526
279 Peru 545 G 526 526
280 Peru 546 G 526 526
281 Peru 547 C 526 526
282 Peru 548 A 526 526
283 Peru 549 T 526 526
284 Peru 550 T 526 526
285 Peru 551 C 526 526
286 Peru 552 A 526 526
287 Peru 553 G 526 526
288 Peru 554 T 526 526
289 Peru 555 A 526 526
290 Peru 556 C 526 526
291 Peru 557 G 526 526
292 Peru 558 G 526 526
293 Peru 559 T C 526 525 Gly98Gly
294 Peru 560 C 526 526
295 Peru 561 G 526 526
296 Peru 562 T 526 526
297 Peru 563 A 526 526
298 Peru 564 G 526 526
299 Peru 565 T 528 528
300 Peru 566 G 528 528
301 Peru 567 G 528 528
302 Peru 568 T 528 528
303 Peru 569 G 528 528
304 Peru 570 A 528 528
305 Peru 571 G 528 528
306 Peru 572 A 528 528
307 Peru 573 C 528 528
308 Peru 574 A 528 528
309 Peru 575 C 528 528
310 Peru 576 T 528 528
311 Peru 577 T 528 528
312 Peru 578 G 528 528
313 Peru 579 G 528 528
314 Peru 580 T 528 528
315 Peru 581 G 528 528
316 Peru 582 T 528 528
317 Peru 583 C T 528 526 Val106Val
318 Peru 584 C 528 528
319 Peru 585 T 528 528
320 Peru 586 T 528 528
321 Peru 587 G 528 528
322 Peru 588 T 528 528
323 Peru 589 C 528 528
324 Peru 590 C 528 528
325 Peru 591 C 528 528
326 Peru 592 T 528 528
327 Peru 593 C T 528 524 His110Tyr
328 Peru 594 A 528 528
329 Peru 595 T 528 528
330 Peru 596 G 528 528
331 Peru 597 T 528 528
332 Peru 598 G 528 528
333 Peru 599 G 528 528
334 Peru 600 G 528 528
335 Peru 601 C T 528 526 Gly112Gly
336 Peru 602 G A 528 526 Glu113Lys
337 Peru 603 A 528 528
338 Peru 604 A 528 528
339 Peru 605 A 528 528
340 Peru 606 T 528 528
341 Peru 607 A 528 528
342 Peru 608 C 528 528
343 Peru 609 C 528 528
344 Peru 610 A 528 528
345 Peru 611 G 528 528
346 Peru 612 T 528 528
347 Peru 613 G 528 528
348 Peru 614 G 528 528
349 Peru 615 C 528 528
350 Peru 616 T 528 528
351 Peru 617 T 528 528
352 Peru 618 A 528 528
353 Peru 619 C 528 528
354 Peru 620 C 528 528
355 Peru 621 G 528 528
356 Peru 622 C 528 528
357 Peru 623 A 528 528
358 Peru 624 A 528 528
359 Peru 625 G 528 528
360 Peru 626 G 528 528
361 Peru 627 T 528 528
362 Peru 628 T 528 528
363 Peru 629 C 528 528
364 Peru 630 T 528 528
365 Peru 631 T 528 528
366 Peru 632 C 528 528
367 Peru 633 T 528 528
368 Peru 634 T 528 528
369 Peru 635 C 528 528
370 Peru 636 G 528 528
371 Peru 637 T 528 528
372 Peru 638 A 528 528
373 Peru 639 A 528 528
374 Peru 640 G 528 528
375 Peru 641 A 528 528
376 Peru 642 A 528 528
377 Peru 643 C 528 528
378 Peru 644 G 528 528
379 Peru 645 G 528 528
380 Peru 646 T 528 528
381 Peru 647 A 528 528
382 Peru 648 A 528 528
383 Peru 649 T 528 528
384 Peru 650 A 528 528
385 Peru 651 A 528 528
386 Peru 652 A 528 528
387 Peru 653 G 528 528
388 Peru 654 G 528 528
389 Peru 655 A 528 528
390 Peru 656 G 528 528
391 Peru 657 C 528 528
392 Peru 658 T 528 528
393 Peru 659 G 528 528
394 Peru 660 G 528 528
395 Peru 661 T 528 528
396 Peru 662 G 528 528
397 Peru 663 G 528 528
398 Peru 664 C 528 528
399 Peru 665 C 528 528
400 Peru 666 A 528 528
401 Peru 667 T 528 528
402 Peru 668 A 528 528
403 Peru 669 G 528 528
404 Peru 670 T 528 528
405 Peru 671 T 528 528
406 Peru 672 A 528 528
407 Peru 673 C 528 528
408 Peru 674 G 528 528
409 Peru 675 G T 528 527 Gly137Val
410 Peru 676 C 528 528
411 Peru 677 G 528 528
412 Peru 678 C 528 528
413 Peru 679 C 528 528
414 Peru 680 G 528 528
415 Peru 681 A 528 528
416 Peru 682 T 528 528
417 Peru 683 C T 528 525 Leu140Leu
418 Peru 684 T 528 528
419 Peru 685 A 528 528
420 Peru 686 A 528 526
421 Peru 687 A 528 526
422 Peru 688 G 528 526
423 Peru 689 T 528 526
424 Peru 690 C T 528 525 Ser142Leu
425 Peru 691 A 528 526
426 Peru 692 T 528 526
427 Peru 693 T 528 526
428 Peru 694 T 528 526
429 Peru 695 G 528 528
430 Peru 696 A 528 528
431 Peru 697 C 528 528
432 Peru 698 T 528 528
433 Peru 699 T 528 528
434 Peru 700 A 528 528
435 Peru 701 G 528 528
436 Peru 702 G 528 528
437 Peru 703 C 528 528
438 Peru 704 G 528 528
439 Peru 705 A 528 528
440 Peru 706 C 528 528
441 Peru 707 G 528 528
442 Peru 708 A 528 528
443 Peru 709 G A 528 527 Glu148Glu
444 Peru 710 C 528 528
445 Peru 711 T 528 528
446 Peru 712 T 528 528
447 Peru 713 G T 528 527 Gly150Cys
448 Peru 714 G 528 528
449 Peru 715 C 528 528
450 Peru 716 A 528 528
451 Peru 717 C 528 528
452 Peru 718 T 528 528
453 Peru 719 G 528 528
454 Peru 720 A 528 528
455 Peru 721 T 528 528
456 Peru 722 C 528 528
457 Peru 723 C 528 528
458 Peru 724 T 528 528
459 Peru 725 T 528 528
460 Peru 726 A 528 528
461 Peru 727 T 528 528
462 Peru 728 G 528 528
463 Peru 729 A 528 528
464 Peru 730 A 528 528
465 Peru 731 G 528 528
466 Peru 732 A 528 528
467 Peru 733 T 528 528
468 Peru 734 T 528 528
469 Peru 735 T 528 528
470 Peru 736 T 528 528
471 Peru 737 C 528 528
472 Peru 738 A 528 528
473 Peru 739 A 528 528
474 Peru 740 G 528 528
475 Peru 741 A 528 528
476 Peru 742 A 528 528
477 Peru 743 A 528 528
478 Peru 744 A 528 528
479 Peru 745 C T 528 523 Asn160Asn
480 Peru 746 T 528 528
481 Peru 747 G 528 528
482 Peru 748 G 528 528
483 Peru 749 A 528 528
484 Peru 750 A 528 528
485 Peru 751 C 528 528
486 Peru 752 A 528 528
487 Peru 753 C 528 528
488 Peru 754 T 528 528
489 Peru 755 A 528 528
490 Peru 756 A 528 528
491 Peru 757 A 528 528
492 Peru 758 C 528 528
493 Peru 759 A 528 528
494 Peru 760 T 528 528
495 Peru 761 A 528 528
496 Peru 762 G 528 528
497 Peru 763 C 528 528
498 Peru 764 A 528 528
499 Peru 765 G 528 528
500 Peru 766 T 528 528
501 Peru 767 G 528 528
502 Peru 768 G 528 528
503 Peru 769 T 528 528
504 Peru 770 G 528 528
505 Peru 771 T 528 528
506 Peru 772 T 528 528
507 Peru 773 A 528 528
508 Peru 774 C 528 528
509 Peru 775 C 528 528
510 Peru 776 C 528 528
511 Peru 777 G 528 528
512 Peru 778 T 528 528
513 Peru 779 G 528 528
514 Peru 780 A 528 528
515 Peru 781 A 528 528
516 Peru 782 C 528 528
517 Peru 783 T 528 528
518 Peru 784 C 528 528
519 Peru 785 A 528 528
520 Peru 786 T 528 528
521 Peru 787 G 528 528
522 Peru 788 C 528 528
523 Peru 789 G 528 528
524 Peru 790 T 528 528
525 Peru 791 G 528 528
526 Peru 792 A 528 528
527 Peru 793 G 528 528
528 Peru 794 C 528 528
529 Peru 795 T 528 528
530 Peru 796 T 528 528
531 Peru 797 A 528 528
532 Peru 798 A G 528 527 Asn178Ser
533 Peru 799 C 528 528
534 Peru 800 G 528 528
535 Peru 801 G 528 528
536 Peru 802 A 528 528
537 Peru 803 G 528 528
538 Peru 804 G 528 528
539 Peru 805 G 528 528