National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
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Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P R S T V Y
*     2                                    
-     228                                    
?                                          
A     12 1                           1   2  
C     9                                    
D     3                       1           1
E     6     1                              
F     15         2         1                
G     3                                    
H                                          
I     9                                    
K     6                                    
L     43         3     1   3                
M     3                                    
N     15                       2            
P     6                   1                
R     9             1 1           1   1    
S     24         1         1         2      
T     12 1             1               2    
V     39         1     2   3             3  
Y     12                                   1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Switzerland 26245 A 8066 8066
1 Switzerland 26246 T 8066 8066
2 Switzerland 26247 G 8066 8064
3 Switzerland 26248 T 8066 8066
4 Switzerland 26249 A 8066 8066
5 Switzerland 26250 C 8066 8066
6 Switzerland 26251 T 8066 8066
7 Switzerland 26252 C T 8066 8065 Ser3Leu
8 Switzerland 26253 A 8066 8066
9 Switzerland 26254 T 8066 8066
10 Switzerland 26255 T 8066 8062
11 Switzerland 26256 C T 8066 8056 Phe4Phe
12 Switzerland 26257 G C 8066 8063 Val5Leu
13 Switzerland 26258 T 8066 8066
14 Switzerland 26259 T 8066 8066
15 Switzerland 26260 T 8066 8066
16 Switzerland 26261 C 8066 8065
17 Switzerland 26262 G 8066 8063
18 Switzerland 26263 G 8066 8064
19 Switzerland 26264 A 8066 8066
20 Switzerland 26265 A 8066 8064
21 Switzerland 26266 G 8066 8064
22 Switzerland 26267 A 8066 8066
23 Switzerland 26268 G T 8066 8064 Glu8Asp
24 Switzerland 26269 A 8066 8065
25 Switzerland 26270 C T 8066 8054 Thr9Ile
26 Switzerland 26271 A G 8066 8065 Thr9Thr
27 Switzerland 26272 G 8066 8065
28 Switzerland 26273 G 8066 8065
29 Switzerland 26274 T 8066 8066
30 Switzerland 26275 A 8066 8066
31 Switzerland 26276 C 8066 8066
32 Switzerland 26277 G A 8066 8063 Thr11Thr
33 Switzerland 26278 T 8066 8065
34 Switzerland 26279 T 8065 8065
35 Switzerland 26280 A 8065 8064
36 Switzerland 26281 A 8065 8065
37 Switzerland 26282 T 8065 8065
38 Switzerland 26283 A 8065 8065
39 Switzerland 26284 G A 8065 8064 Val14Ile
40 Switzerland 26285 T 8065 8065
41 Switzerland 26286 T C 8065 8063 Val14Val
42 Switzerland 26287 A 8065 8065
43 Switzerland 26288 A 8065 8065
44 Switzerland 26289 T C 8065 8063 Asn15Asn
45 Switzerland 26290 A 8065 8065
46 Switzerland 26291 G 8065 8065
47 Switzerland 26292 C 8063 8062
48 Switzerland 26293 G 8063 8063
49 Switzerland 26294 T 8063 8063
50 Switzerland 26295 A 8063 8063
51 Switzerland 26296 C 8063 8062
52 Switzerland 26297 T 8061 8061
53 Switzerland 26298 T 8061 8061
54 Switzerland 26299 C 8061 8061
55 Switzerland 26300 T 8055 8053
56 Switzerland 26301 T 8055 8054
57 Switzerland 26302 T 8054 8054
58 Switzerland 26303 T 8053 8053
59 Switzerland 26304 T 8053 8053
60 Switzerland 26305 C 8049 8049
61 Switzerland 26306 T 8041 8038
62 Switzerland 26307 T 8034 8025
63 Switzerland 26308 G 8034 8025
64 Switzerland 26309 C T 8034 8022 Ala22Val
65 Switzerland 26310 T 8034 8023
66 Switzerland 26311 T 8033 8023
67 Switzerland 26312 T 8033 8024
68 Switzerland 26313 C T 8033 7999 Phe23Phe
69 Switzerland 26314 G 8033 8023
70 Switzerland 26315 T 8030 8020
71 Switzerland 26316 G 7898 7831
72 Switzerland 26317 G 7898 7833
73 Switzerland 26318 T 7898 7832
74 Switzerland 26319 A G 7898 7814 Val25Val
75 Switzerland 26320 T C 7898 7835 Phe26Leu
76 Switzerland 26321 T 7898 7835
77 Switzerland 26322 C 7897 7835
78 Switzerland 26323 T 7897 7835
79 Switzerland 26324 T 7897 7836
80 Switzerland 26325 G A 7897 7832 Leu27Leu
81 Switzerland 26326 C T 7897 7835 Leu28Leu
82 Switzerland 26327 T 7897 7836
83 Switzerland 26328 A 7897 7837
84 Switzerland 26329 G 7897 7837
85 Switzerland 26330 T 7897 7840
86 Switzerland 26331 T 7897 7839
87 Switzerland 26332 A 7897 7839
88 Switzerland 26333 C 7897 7838
89 Switzerland 26334 A 7897 7841
90 Switzerland 26335 C 7897 7842
91 Switzerland 26336 T 7897 7840
92 Switzerland 26337 A 7897 7841
93 Switzerland 26338 G 7897 7844
94 Switzerland 26339 C 7897 7848
95 Switzerland 26340 C T 7897 7869 Ala32Ala
96 Switzerland 26341 A 7897 7883
97 Switzerland 26342 T 7897 7887
98 Switzerland 26343 C 7897 7888
99 Switzerland 26344 C 7897 7887
100 Switzerland 26345 T 7897 7889
101 Switzerland 26346 T 7897 7890
102 Switzerland 26347 A G 7897 7889 Thr35Ala
103 Switzerland 26348 C 7897 7891
104 Switzerland 26349 T 7897 7891
105 Switzerland 26350 G 7897 7889
106 Switzerland 26351 C 7897 7892
107 Switzerland 26352 G 7897 7890
108 Switzerland 26353 C T 7897 7892 Leu37Phe
109 Switzerland 26354 T 7897 7894
110 Switzerland 26355 T 7897 7892
111 Switzerland 26356 C 7897 7895
112 Switzerland 26357 G 7897 7892
113 Switzerland 26358 A 7897 7893
114 Switzerland 26359 T 7897 7892
115 Switzerland 26360 T 7898 7897
116 Switzerland 26361 G 7898 7895
117 Switzerland 26362 T 7898 7897
118 Switzerland 26363 G 7898 7896
119 Switzerland 26364 T 7898 7896
120 Switzerland 26365 G T 7898 7894 Ala41Ser
121 Switzerland 26366 C T 7898 7889 Ala41Val
122 Switzerland 26367 G 7898 7895
123 Switzerland 26368 T 7898 7897
124 Switzerland 26369 A 7898 7895
125 Switzerland 26370 C T 7898 7891 Tyr42Tyr
126 Switzerland 26371 T 7898 7893
127 Switzerland 26372 G 7898 7892
128 Switzerland 26373 C 7898 7896
129 Switzerland 26374 T 7898 7895
130 Switzerland 26375 G 7898 7896
131 Switzerland 26376 C 7898 7895
132 Switzerland 26377 A 7899 7895
133 Switzerland 26378 A 7899 7896
134 Switzerland 26379 T 7899 7897
135 Switzerland 26380 A 7899 7896
136 Switzerland 26381 T 7899 7895
137 Switzerland 26382 T 7899 7895
138 Switzerland 26383 G 7899 7896
139 Switzerland 26384 T 7900 7896
140 Switzerland 26385 T 7900 7898
141 Switzerland 26386 A 7900 7895
142 Switzerland 26387 A 7901 7893
143 Switzerland 26388 C 7901 7897
144 Switzerland 26389 G T 7901 7893 Val49Leu
145 Switzerland 26390 T 7901 7898
146 Switzerland 26391 G 7901 7899
147 Switzerland 26392 A 7901 7899
148 Switzerland 26393 G 7901 7893
149 Switzerland 26394 T 7901 7895
150 Switzerland 26395 C T,A 7901 7890 Leu51Phe-p.Leu51Ile
151 Switzerland 26396 T 7901 7893
152 Switzerland 26397 T 7901 7892
153 Switzerland 26398 G 7901 7895
154 Switzerland 26399 T 7901 7900
155 Switzerland 26400 A 7901 7901
156 Switzerland 26401 A 7901 7900
157 Switzerland 26402 A 7901 7900
158 Switzerland 26403 A 7901 7900
159 Switzerland 26404 C 7901 7895
160 Switzerland 26405 C 7901 7898
161 Switzerland 26406 T 7901 7901
162 Switzerland 26407 T 7901 7898
163 Switzerland 26408 C 7901 7898
164 Switzerland 26409 T 7901 7895
165 Switzerland 26410 T 7901 7899
166 Switzerland 26411 T 7901 7900
167 Switzerland 26412 T 7901 7901
168 Switzerland 26413 T 7901 7900
169 Switzerland 26414 A 7901 7899
170 Switzerland 26415 C 7901 7901
171 Switzerland 26416 G 7901 7900
172 Switzerland 26417 T 7901 7901
173 Switzerland 26418 T 7900 7899
174 Switzerland 26419 T 7900 7899
175 Switzerland 26420 A 7900 7900
176 Switzerland 26421 C 7900 7900
177 Switzerland 26422 T 7900 7899
178 Switzerland 26423 C 7900 7899
179 Switzerland 26424 T C 7900 7897 Ser60Ser
180 Switzerland 26425 C 7900 7897
181 Switzerland 26426 G A 7900 7894 Arg61His
182 Switzerland 26427 T 7900 7899
183 Switzerland 26428 G T 7900 7893 Val62Phe
184 Switzerland 26429 T 7900 7899
185 Switzerland 26430 T 7899 7897
186 Switzerland 26431 A 7899 7897
187 Switzerland 26432 A 7898 7892
188 Switzerland 26433 A 7898 7896
189 Switzerland 26434 A 7898 7893
190 Switzerland 26435 A 7898 7897
191 Switzerland 26436 T C 7898 7893 Asn64Asn
192 Switzerland 26437 C 7898 7897
193 Switzerland 26438 T 7898 7897
194 Switzerland 26439 G 7898 7897
195 Switzerland 26440 A 7898 7898
196 Switzerland 26441 A 7895 7895
197 Switzerland 26442 T 7894 7894
198 Switzerland 26443 T 7894 7894
199 Switzerland 26444 C 7894 7894
200 Switzerland 26445 T 7894 7893
201 Switzerland 26446 T 7894 7893
202 Switzerland 26447 C T 7894 7881 Ser68Phe
203 Switzerland 26448 T C 7888 7882 Ser68Ser
204 Switzerland 26449 A C 7844 7840 Arg69Arg
205 Switzerland 26450 G T,C 7843 7830 Arg69Ile-p.Arg69Thr
206 Switzerland 26451 A 7843 7843
207 Switzerland 26452 G A 7842 7840 Val70Ile
208 Switzerland 26453 T 7842 7840
209 Switzerland 26454 T 7842 7841
210 Switzerland 26455 C 7842 7840
211 Switzerland 26456 C T 7842 7824 Pro71Leu
212 Switzerland 26457 T 7842 7841
213 Switzerland 26458 G T,A 7842 7837 Asp72Tyr-p.Asp72Asn
214 Switzerland 26459 A 7841 7839
215 Switzerland 26460 T 7841 7841
216 Switzerland 26461 C T 7841 7834 Leu73Phe
217 Switzerland 26462 T 7841 7838
218 Switzerland 26463 T 7841 7841
219 Switzerland 26464 C T 7840 7824 Leu74Leu
220 Switzerland 26465 T 7840 7840
221 Switzerland 26466 G 7840 7840
222 Switzerland 26467 G C 7840 7829 Val75Leu
223 Switzerland 26468 T 7840 7840
224 Switzerland 26469 C T 7839 7836 Val75Val
225 Switzerland 26470 T 7839 7838
226 Switzerland 26471 A 7839 7839
227 Switzerland 26472 A 7837 7837