National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.

Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A C D E F G H I K L M N P R S T V Y
*     2                                    
-     228                                    
?                                          
A     12 2                             1 1  
C     9                                    
D     3                                   1
E     6     2                              
F     15         2                          
G     3           1                        
H                                          
I     9                                    
K     6                                    
L     43         3         3                
M     3                                    
N     15                       1            
P     6                   1         2      
R     9                               1    
S     24   1     3                   2      
T     12 1             1                    
V     39         1     1   2 1           1  
Y     12             1                     2

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide

Contoury Position Reference Alt. NSR NS AAchange
0 Netherlands 26245 A 5847 5847
1 Netherlands 26246 T 5847 5847
2 Netherlands 26247 G 5847 5847
3 Netherlands 26248 T 5847 5847
4 Netherlands 26249 A 5847 5847
5 Netherlands 26250 C T 5847 5846 Tyr2Tyr
6 Netherlands 26251 T 5847 5847
7 Netherlands 26252 C 5847 5847
8 Netherlands 26253 A 5847 5847
9 Netherlands 26254 T 5847 5847
10 Netherlands 26255 T 5847 5847
11 Netherlands 26256 C T 5847 5845 Phe4Phe
12 Netherlands 26257 G A 5847 5846 Val5Ile
13 Netherlands 26258 T 5847 5847
14 Netherlands 26259 T 5847 5847
15 Netherlands 26260 T 5847 5847
16 Netherlands 26261 C 5847 5847
17 Netherlands 26262 G T,A 5847 5834 Ser6Ser-p.Ser6Ser
18 Netherlands 26263 G 5847 5847
19 Netherlands 26264 A 5847 5847
20 Netherlands 26265 A 5847 5847
21 Netherlands 26266 G 5847 5847
22 Netherlands 26267 A 5847 5847
23 Netherlands 26268 G T,C 5847 5845 Glu8Asp-p.Glu8Asp
24 Netherlands 26269 A 5847 5847
25 Netherlands 26270 C 5847 5847
26 Netherlands 26271 A 5847 5847
27 Netherlands 26272 G 5847 5847
28 Netherlands 26273 G 5847 5847
29 Netherlands 26274 T C 5847 5846 Gly10Gly
30 Netherlands 26275 A G 5847 5846 Thr11Ala
31 Netherlands 26276 C 5847 5847
32 Netherlands 26277 G 5847 5847
33 Netherlands 26278 T 5847 5847
34 Netherlands 26279 T 5847 5847
35 Netherlands 26280 A 5847 5847
36 Netherlands 26281 A 5847 5847
37 Netherlands 26282 T 5847 5847
38 Netherlands 26283 A 5847 5847
39 Netherlands 26284 G 5847 5847
40 Netherlands 26285 T 5847 5847
41 Netherlands 26286 T 5847 5847
42 Netherlands 26287 A 5847 5847
43 Netherlands 26288 A 5847 5847
44 Netherlands 26289 T 5847 5847
45 Netherlands 26290 A 5847 5847
46 Netherlands 26291 G 5847 5847
47 Netherlands 26292 C 5847 5847
48 Netherlands 26293 G 5847 5847
49 Netherlands 26294 T 5847 5847
50 Netherlands 26295 A 5847 5847
51 Netherlands 26296 C 5847 5847
52 Netherlands 26297 T 5847 5847
53 Netherlands 26298 T 5847 5847
54 Netherlands 26299 C 5847 5847
55 Netherlands 26300 T 5847 5847
56 Netherlands 26301 T 5847 5847
57 Netherlands 26302 T 5847 5847
58 Netherlands 26303 T 5847 5847
59 Netherlands 26304 T 5847 5847
60 Netherlands 26305 C T 5847 5842 Leu21Phe
61 Netherlands 26306 T 5847 5847
62 Netherlands 26307 T 5847 5847
63 Netherlands 26308 G 5847 5847
64 Netherlands 26309 C 5847 5847
65 Netherlands 26310 T 5847 5847
66 Netherlands 26311 T 5847 5847
67 Netherlands 26312 T 5847 5847
68 Netherlands 26313 C T 5847 5738 Phe23Phe
69 Netherlands 26314 G A,T 5846 5843 Val24Met-p.Val24Leu
70 Netherlands 26315 T 5846 5846
71 Netherlands 26316 G 5846 5846
72 Netherlands 26317 G 5846 5846
73 Netherlands 26318 T 5846 5846
74 Netherlands 26319 A G 5846 5841 Val25Val
75 Netherlands 26320 T 5846 5846
76 Netherlands 26321 T 5846 5846
77 Netherlands 26322 C 5846 5846
78 Netherlands 26323 T 5846 5846
79 Netherlands 26324 T 5846 5846
80 Netherlands 26325 G 5846 5846
81 Netherlands 26326 C T 5846 5840 Leu28Leu
82 Netherlands 26327 T 5846 5846
83 Netherlands 26328 A 5846 5846
84 Netherlands 26329 G 5846 5846
85 Netherlands 26330 T 5846 5846
86 Netherlands 26331 T 5846 5846
87 Netherlands 26332 A 5846 5846
88 Netherlands 26333 C T 5846 5842 Thr30Ile
89 Netherlands 26334 A 5846 5846
90 Netherlands 26335 C 5846 5846
91 Netherlands 26336 T 5846 5846
92 Netherlands 26337 A 5846 5846
93 Netherlands 26338 G A 5846 5845 Ala32Thr
94 Netherlands 26339 C 5846 5846
95 Netherlands 26340 C T 5846 5845 Ala32Ala
96 Netherlands 26341 A 5846 5846
97 Netherlands 26342 T 5846 5846
98 Netherlands 26343 C 5846 5846
99 Netherlands 26344 C 5846 5846
100 Netherlands 26345 T 5846 5846
101 Netherlands 26346 T 5846 5846
102 Netherlands 26347 A 5846 5846
103 Netherlands 26348 C 5846 5846
104 Netherlands 26349 T 5846 5846
105 Netherlands 26350 G 5846 5846
106 Netherlands 26351 C T 5846 5845 Ala36Val
107 Netherlands 26352 G 5846 5846
108 Netherlands 26353 C T 5846 5844 Leu37Phe
109 Netherlands 26354 T 5846 5846
110 Netherlands 26355 T 5846 5846
111 Netherlands 26356 C 5846 5846
112 Netherlands 26357 G 5846 5846
113 Netherlands 26358 A 5846 5846
114 Netherlands 26359 T 5846 5846
115 Netherlands 26360 T 5846 5846
116 Netherlands 26361 G 5846 5846
117 Netherlands 26362 T 5846 5846
118 Netherlands 26363 G 5846 5846
119 Netherlands 26364 T 5846 5846
120 Netherlands 26365 G 5846 5846
121 Netherlands 26366 C 5846 5846
122 Netherlands 26367 G T 5846 5845 Ala41Ala
123 Netherlands 26368 T 5846 5846
124 Netherlands 26369 A 5846 5846
125 Netherlands 26370 C 5846 5846
126 Netherlands 26371 T 5846 5846
127 Netherlands 26372 G 5846 5846
128 Netherlands 26373 C 5846 5846
129 Netherlands 26374 T 5846 5846
130 Netherlands 26375 G 5846 5846
131 Netherlands 26376 C 5846 5846
132 Netherlands 26377 A 5846 5846
133 Netherlands 26378 A 5846 5846
134 Netherlands 26379 T 5846 5846
135 Netherlands 26380 A 5846 5846
136 Netherlands 26381 T 5846 5846
137 Netherlands 26382 T 5846 5846
138 Netherlands 26383 G 5846 5845
139 Netherlands 26384 T 5846 5845
140 Netherlands 26385 T 5846 5845
141 Netherlands 26386 A 5846 5846
142 Netherlands 26387 A 5850 5850
143 Netherlands 26388 C 5850 5850
144 Netherlands 26389 G T 5850 5848 Val49Leu
145 Netherlands 26390 T 5851 5851
146 Netherlands 26391 G 5851 5851
147 Netherlands 26392 A T 5851 5850 Ser50Cys
148 Netherlands 26393 G 5851 5851
149 Netherlands 26394 T 5851 5851
150 Netherlands 26395 C 5851 5851
151 Netherlands 26396 T 5851 5851
152 Netherlands 26397 T 5851 5851
153 Netherlands 26398 G 5852 5852
154 Netherlands 26399 T 5853 5853
155 Netherlands 26400 A 5854 5854
156 Netherlands 26401 A 5854 5854
157 Netherlands 26402 A 5854 5854
158 Netherlands 26403 A 5856 5856
159 Netherlands 26404 C T 5856 5855 Pro54Ser
160 Netherlands 26405 C 5856 5856
161 Netherlands 26406 T 5856 5856
162 Netherlands 26407 T 5856 5856
163 Netherlands 26408 C T 5857 5831 Ser55Phe
164 Netherlands 26409 T 5858 5858
165 Netherlands 26410 T 5859 5859
166 Netherlands 26411 T 5859 5859
167 Netherlands 26412 T 5860 5860
168 Netherlands 26413 T 5860 5860
169 Netherlands 26414 A 5882 5882
170 Netherlands 26415 C T 5882 5881 Tyr57Tyr
171 Netherlands 26416 G 5882 5882
172 Netherlands 26417 T 5882 5882
173 Netherlands 26418 T 5882 5882
174 Netherlands 26419 T C 5882 5881 Tyr59His
175 Netherlands 26420 A 5882 5882
176 Netherlands 26421 C 5882 5882
177 Netherlands 26422 T 5882 5882
178 Netherlands 26423 C 5882 5882
179 Netherlands 26424 T 5882 5882
180 Netherlands 26425 C 5882 5882
181 Netherlands 26426 G 5882 5882
182 Netherlands 26427 T 5882 5882
183 Netherlands 26428 G T 5882 5877 Val62Phe
184 Netherlands 26429 T 5882 5882
185 Netherlands 26430 T 5882 5882
186 Netherlands 26431 A 5882 5882
187 Netherlands 26432 A 5882 5882
188 Netherlands 26433 A 5882 5882
189 Netherlands 26434 A 5882 5882
190 Netherlands 26435 A 5882 5882
191 Netherlands 26436 T C 5882 5881 Asn64Asn
192 Netherlands 26437 C 5882 5882
193 Netherlands 26438 T 5882 5882
194 Netherlands 26439 G T 5882 5877 Leu65Leu
195 Netherlands 26440 A 5882 5882
196 Netherlands 26441 A 5882 5882
197 Netherlands 26442 T 5882 5882
198 Netherlands 26443 T 5882 5882
199 Netherlands 26444 C T 5882 5881 Ser67Phe
200 Netherlands 26445 T 5882 5882
201 Netherlands 26446 T 5882 5882
202 Netherlands 26447 C T 5882 5880 Ser68Phe
203 Netherlands 26448 T 5882 5882
204 Netherlands 26449 A 5882 5882
205 Netherlands 26450 G C 5882 5881 Arg69Thr
206 Netherlands 26451 A 5882 5882
207 Netherlands 26452 G 5882 5882
208 Netherlands 26453 T 5882 5882
209 Netherlands 26454 T 5882 5882
210 Netherlands 26455 C T 5882 5881 Pro71Ser
211 Netherlands 26456 C T 5882 5874 Pro71Leu
212 Netherlands 26457 T 5882 5882
213 Netherlands 26458 G T 5882 5881 Asp72Tyr
214 Netherlands 26459 A 5882 5882
215 Netherlands 26460 T 5882 5882
216 Netherlands 26461 C T 5882 5868 Leu73Phe
217 Netherlands 26462 T 5882 5882
218 Netherlands 26463 T 5882 5882
219 Netherlands 26464 C T 5882 5878 Leu74Leu
220 Netherlands 26465 T 5882 5882
221 Netherlands 26466 G 5882 5882
222 Netherlands 26467 G 5882 5882
223 Netherlands 26468 T 5882 5882
224 Netherlands 26469 C 5882 5882
225 Netherlands 26470 T 5882 5882
226 Netherlands 26471 A 5882 5882
227 Netherlands 26472 A 5882 5882