National Institute Of Genetic Engineering and Biotechnology

P.I:Mohammad-Ali Malboobi
Here we provide last mutation observed in Nucleocapsid gene of COVID-19 prevalent in Iran.
We kindly wait your comment or coopration in tracking crona virus project.
Amino acid changes

How to read this table:
- Rows are reference amino acids and columns are changed amino acids. E.g. Row 'A' column 'E' indicates how many 'A' amino acids have been replaced by 'E' amino acids.
- Red background colors indicate that more changes happened (heat-map).
- Diagonals are indicated using grey background color
- WARNING: This table may include different translation codon tables (e.g. mamalian DNA and mitochondrial DNA).

  * - ? A D E F H I K L M N P Q R S T V W Y
*     2                                    
-     186                                    
?                                          
A     3 1                                  
D     12   1                               1
E     16   1                                
F     9               1                    
H     3                                   1
I     30       1   2             1   2      
K     12     1             1                
L     24               3               1    
M     9                               1    
N     12                                    
P     3                                    
Q     9                                    
R     3                           1        
S     12                                    
T     9           1                        
V     9       2                            
W     3               1                    
Y     6         1                         1

Nucleotide and amino acid mutations

Here we provide list of mutation observed in Nucleocapsid at gene and protein of COVID-19.
-The position column is nucleotide position in reference genome as NC_045512.2
-The Reference column indicate reference nucleotide in NC_045512.2
-The NS column indicate number of samples that this position have been observed
-The NSR column indicate number of samples with reference nucleotide. Therefore diffrenciate related to Ns indicate number of sample with mutated nucleotide
Contoury Position Reference Alt. NSR NS AAchange
0 Brazil 27202 A 2149 2149
1 Brazil 27203 T 2149 2149
2 Brazil 27204 G 2149 2149
3 Brazil 27205 T C 2149 2148 Phe2Leu
4 Brazil 27206 T 2152 2152
5 Brazil 27207 T 2152 2152
6 Brazil 27208 C T 2152 2151 His3Tyr
7 Brazil 27209 A 2152 2152
8 Brazil 27210 T 2152 2152
9 Brazil 27211 C 2152 2152
10 Brazil 27212 T 2152 2152
11 Brazil 27213 C T 2152 2147 Leu4Leu
12 Brazil 27214 G T 2152 2151 Val5Phe
13 Brazil 27215 T 2152 2152
14 Brazil 27216 T 2152 2152
15 Brazil 27217 G 2152 2152
16 Brazil 27218 A 2152 2152
17 Brazil 27219 C 2152 2152
18 Brazil 27220 T 2152 2152
19 Brazil 27221 T 2152 2152
20 Brazil 27222 T 2152 2152
21 Brazil 27223 C 2152 2152
22 Brazil 27224 A 2152 2152
23 Brazil 27225 G 2152 2152
24 Brazil 27226 G 2152 2152
25 Brazil 27227 T 2152 2152
26 Brazil 27228 T 2152 2152
27 Brazil 27229 A 2152 2152
28 Brazil 27230 C 2153 2153
29 Brazil 27231 T 2153 2153
30 Brazil 27232 A 2153 2153
31 Brazil 27233 T G 2153 2152 Ile11Arg
32 Brazil 27234 A 2153 2153
33 Brazil 27235 G 2153 2153
34 Brazil 27236 C 2153 2153
35 Brazil 27237 A G 2153 2151 Ala12Ala
36 Brazil 27238 G 2153 2153
37 Brazil 27239 A 2153 2153
38 Brazil 27240 G T 2153 2142 Glu13Asp
39 Brazil 27241 A 2154 2154
40 Brazil 27242 T 2154 2154
41 Brazil 27243 A 2154 2154
42 Brazil 27244 T G 2154 2153 Leu15Val
43 Brazil 27245 T 2154 2154
44 Brazil 27246 A 2154 2154
45 Brazil 27247 C T 2154 2153 Leu16Leu
46 Brazil 27248 T 2153 2153
47 Brazil 27249 A 2153 2153
48 Brazil 27250 A 2153 2153
49 Brazil 27251 T 2153 2153
50 Brazil 27252 T 2153 2153
51 Brazil 27253 A 2153 2153
52 Brazil 27254 T 2153 2153
53 Brazil 27255 T 2153 2153
54 Brazil 27256 A G 2154 2151 Met19Val
55 Brazil 27257 T 2154 2154
56 Brazil 27258 G 2154 2154
57 Brazil 27259 A 2154 2154
58 Brazil 27260 G 2154 2154
59 Brazil 27261 G T 2154 2153 Arg20Ser
60 Brazil 27262 A 2153 2153
61 Brazil 27263 C T 2153 2152 Thr21Ile
62 Brazil 27264 T 2153 2153
63 Brazil 27265 T 2153 2153
64 Brazil 27266 T 2153 2153
65 Brazil 27267 T 2153 2153
66 Brazil 27268 A 2153 2153
67 Brazil 27269 A 2153 2153
68 Brazil 27270 A 2153 2153
69 Brazil 27271 G T 2153 2151 Val24Phe
70 Brazil 27272 T 2153 2153
71 Brazil 27273 T 2153 2153
72 Brazil 27274 T 2153 2153
73 Brazil 27275 C 2153 2153
74 Brazil 27276 C 2153 2153
75 Brazil 27277 A 2153 2153
76 Brazil 27278 T 2153 2153
77 Brazil 27279 T 2153 2153
78 Brazil 27280 T 2153 2153
79 Brazil 27281 G T 2153 2150 Trp27Leu
80 Brazil 27282 G 2153 2153
81 Brazil 27283 A 2153 2153
82 Brazil 27284 A 2153 2153
83 Brazil 27285 T 2153 2153
84 Brazil 27286 C 2153 2153
85 Brazil 27287 T 2154 2154
86 Brazil 27288 T 2154 2154
87 Brazil 27289 G 2154 2154
88 Brazil 27290 A 2154 2154
89 Brazil 27291 T 2154 2154
90 Brazil 27292 T 2154 2154
91 Brazil 27293 A 2154 2154
92 Brazil 27294 C T 2154 2153 Tyr31Tyr
93 Brazil 27295 A T 2153 2152 Ile32Phe
94 Brazil 27296 T 2153 2153
95 Brazil 27297 C A,T 2153 2148 Ile32Ile-p.Ile32Ile
96 Brazil 27298 A 2153 2153
97 Brazil 27299 T C 2153 1436 Ile33Thr
98 Brazil 27300 A 2153 2153
99 Brazil 27301 A 2153 2153
100 Brazil 27302 A 2153 2153
101 Brazil 27303 C 2153 2153
102 Brazil 27304 C 2153 2153
103 Brazil 27305 T 2151 2151
104 Brazil 27306 C 2151 2151
105 Brazil 27307 A 2151 2151
106 Brazil 27308 T 2151 2151
107 Brazil 27309 A 2151 2151
108 Brazil 27310 A 2151 2151
109 Brazil 27311 T 2151 2151
110 Brazil 27312 T 2151 2151
111 Brazil 27313 A G 2151 2150 Lys38Glu
112 Brazil 27314 A 2151 2151
113 Brazil 27315 A 2151 2151
114 Brazil 27316 A 2151 2151
115 Brazil 27317 A 2150 2150
116 Brazil 27318 T 2150 2150
117 Brazil 27319 T 2150 2150
118 Brazil 27320 T 2151 2151
119 Brazil 27321 A G 2151 2150 Leu40Leu
120 Brazil 27322 T 2152 2152
121 Brazil 27323 C 2152 2152
122 Brazil 27324 T 2152 2152
123 Brazil 27325 A 2152 2152
124 Brazil 27326 A 2152 2152
125 Brazil 27327 G C 2152 2151 Lys42Asn
126 Brazil 27328 T 2152 2152
127 Brazil 27329 C 2152 2152
128 Brazil 27330 A 2152 2152
129 Brazil 27331 C 2152 2152
130 Brazil 27332 T 2152 2152
131 Brazil 27333 A 2152 2152
132 Brazil 27334 A 2152 2152
133 Brazil 27335 C 2152 2152
134 Brazil 27336 T 2153 2153
135 Brazil 27337 G 2153 2153
136 Brazil 27338 A 2153 2153
137 Brazil 27339 G 2153 2153
138 Brazil 27340 A 2153 2153
139 Brazil 27341 A 2153 2153
140 Brazil 27342 T 2153 2153
141 Brazil 27343 A 2153 2153
142 Brazil 27344 A 2153 2153
143 Brazil 27345 A 2153 2153
144 Brazil 27346 T C 2153 2152 Tyr49His
145 Brazil 27347 A 2153 2153
146 Brazil 27348 T 2153 2153
147 Brazil 27349 T 2153 2153
148 Brazil 27350 C 2153 2153
149 Brazil 27351 T 2153 2153
150 Brazil 27352 C 2153 2153
151 Brazil 27353 A 2153 2153
152 Brazil 27354 A 2153 2153
153 Brazil 27355 T 2154 2154
154 Brazil 27356 T 2154 2154
155 Brazil 27357 A 2154 2154
156 Brazil 27358 G T 2154 2150 Asp53Tyr
157 Brazil 27359 A 2154 2154
158 Brazil 27360 T 2154 2154
159 Brazil 27361 G 2154 2154
160 Brazil 27362 A 2154 2154
161 Brazil 27363 A 2154 2154
162 Brazil 27364 G 2153 2153
163 Brazil 27365 A 2153 2153
164 Brazil 27366 G 2153 2153
165 Brazil 27367 C 2153 2153
166 Brazil 27368 A 2153 2153
167 Brazil 27369 A 2153 2153
168 Brazil 27370 C 2151 2151
169 Brazil 27371 C 2151 2151
170 Brazil 27372 A 2150 2150
171 Brazil 27373 A 2150 2150
172 Brazil 27374 T 2150 2150
173 Brazil 27375 G 2150 2150
174 Brazil 27376 G 2150 2150
175 Brazil 27377 A 2150 2150
176 Brazil 27378 G 2150 2150
177 Brazil 27379 A 2150 2150
178 Brazil 27380 T C 2150 2149 Ile60Thr
179 Brazil 27381 T 2150 2150
180 Brazil 27382 G 2150 2150
181 Brazil 27383 A 2150 2150
182 Brazil 27384 T C 2149 2137 Asp61Asp
183 Brazil 27385 T 2149 2149
184 Brazil 27386 A 2149 2149
185 Brazil 27387 A 2149 2149